Agnete Kirkeby
Agnete Kirkeby
Human Neural Development group, The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW
Verified email at - Homepage
Cited by
Cited by
Direct conversion of human fibroblasts to dopaminergic neurons
U Pfisterer, A Kirkeby, O Torper, J Wood, J Nelander, A Dufour, ...
Proceedings of the National Academy of Sciences 108 (25), 10343-10348, 2011
Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions
A Kirkeby, S Grealish, DA Wolf, J Nelander, J Wood, M Lundblad, ...
Cell reports 1 (6), 703-714, 2012
Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson’s disease
S Grealish, E Diguet, A Kirkeby, B Mattsson, A Heuer, Y Bramoulle, ...
Cell stem cell 15 (5), 653-665, 2014
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease
A Kirkeby, S Nolbrant, K Tiklova, A Heuer, T Kee, Nigel Cardoso, ...
Cell Stem Cell, 2016
Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation
S Nolbrant, A Heuer, M Parmar, A Kirkeby
Nature protocols 12 (9), 1962-1979, 2017
Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages
N Kee, N Volakakis, A Kirkeby, L Dahl, H Storvall, S Nolbrant, L Lahti, ...
Cell Stem Cell, 2016
Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient
P Rifes, M Isaksson, GS Rathore, P Aldrin-Kirk, OK M°ller, G Barzaghi, ...
Nature biotechnology 38 (11), 1265-1273, 2020
Sense-antisense lncRNA pair encoded by locus 6p22. 3 determines neuroblastoma susceptibility via the USP36-CHD7-SOX9 regulatory axis
T Mondal, PK Juvvuna, A Kirkeby, S Mitra, ST Kosalai, L Traxler, ...
Cancer cell 33 (3), 417-434. e7, 2018
Monosynaptic tracing using modified rabies virus reveals early and extensive circuit integration of human embryonic stem cell-derived neurons
S Grealish, A Heuer, T Cardoso, A Kirkeby, M J÷nsson, J Johansson, ...
Stem cell reports 4 (6), 975-983, 2015
Strategies for bringing stem cell-derived dopamine neurons to the clinic: a European approach (STEM-PD)
A Kirkeby, M Parmar, RA Barker
Progress in brain research 230, 165-190, 2017
Are stem cell-based therapies for Parkinson’s disease ready for the clinic in 2016?
RA Barker, M Parmar, A Kirkeby, A Bj÷rklund, L Thompson, P Brundin
Journal of Parkinson's disease 6 (1), 57-63, 2016
Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen–glucose deprivation (OGD) and NMDA excitotoxicityá…
M Montero, FR Poulsen, J Noraberg, A Kirkeby, J van Beek, M Leist, ...
Experimental Neurology 204 (1), 106-117, 2007
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
K Tiklovß, S Nolbrant, A Fiorenzano, ┼K Bj÷rklund, Y Sharma, A Heuer, ...
Nature communications 11 (1), 2434, 2020
The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy
M Leist, S Bremer, P Brundin, J Hescheler, A Kirkeby, KH Krause, ...
Functional and immunochemical characterisation of different antibodies against the erythropoietin receptor
A Kirkeby, J van Beek, J Nielsen, M Leist, L Helboe
Journal of neuroscience methods 164 (1), 50-58, 2007
High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO)
A Kirkeby, L Torup, L Bochsen, M Kjalke, K Abel, K Theilgaard-Monch, ...
Thrombosis and haemostasis 99 (04), 720-728, 2008
Generating regionalized neuronal cells from pluripotency, a step-by-step protocol
A Kirkeby, J Nelander, M Parmar
Frontiers in cellular neuroscience 6, 64, 2013
Therapeutic window for nonerythropoietic carbamylated-erythropoietin to improve motor function following multiple infarct ischemic strokes in New Zealand white rabbits
PA Lapchak, A Kirkeby, JA Zivin, TN Sager
Brain research 1238, 208-214, 2008
Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of Parkinsonian rats
T Cardoso, AF Adler, B Mattsson, DB Hoban, S Nolbrant, JN Wahlestedt, ...
Journal of Comparative Neurology 526 (13), 2133-2146, 2018
IAP-based cell sorting results in homogeneous transplantable dopaminergic precursor cells derived from human pluripotent stem cells
D Lehnen, S Barral, T Cardoso, S Grealish, A Heuer, A Smiyakin, ...
Stem Cell Reports 9 (4), 1207-1220, 2017
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