| Convergent loss of PTEN leads to clinical resistance to a PI (3) Kα inhibitor D Juric, P Castel, M Griffith, OL Griffith, HH Won, H Ellis, SH Ebbesen, ... Nature 518 (7538), 240-244, 2015 | 379 | 2015 |
| CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer M Griffith, NC Spies, K Krysiak, JF McMichael, AC Coffman, AM Danos, ... Nature genetics 49 (2), 170-174, 2017 | 281 | 2017 |
| DGIdb 2.0: mining clinically relevant drug–gene interactions AH Wagner, AC Coffman, BJ Ainscough, NC Spies, ZL Skidmore, ... Nucleic acids research 44 (D1), D1036-D1044, 2016 | 249 | 2016 |
| High-performance web services for querying gene and variant annotation J Xin, A Mark, C Afrasiabi, G Tsueng, M Juchler, N Gopal, GS Stupp, ... Genome biology 17 (1), 1-7, 2016 | 115 | 2016 |
| Genome-wide association study of CSF levels of 59 Alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation JSK Kauwe, MH Bailey, PG Ridge, R Perry, ME Wadsworth, KL Hoyt, ... PLoS Genet 10 (10), e1004758, 2014 | 91 | 2014 |
| Informatics for RNA sequencing: a web resource for analysis on the cloud M Griffith, JR Walker, NC Spies, BJ Ainscough, OL Griffith PLoS Comput Biol 11 (8), e1004393, 2015 | 84 | 2015 |
| Genome modeling system: a knowledge management platform for genomics M Griffith, OL Griffith, SM Smith, A Ramu, MB Callaway, AM Brummett, ... PLoS computational biology 11 (7), e1004274, 2015 | 69 | 2015 |
| Organizing knowledge to enable personalization of medicine in cancer BM Good, BJ Ainscough, JF McMichael, AI Su, OL Griffith Genome biology 15 (8), 1-9, 2014 | 69 | 2014 |
| DoCM: a database of curated mutations in cancer BJ Ainscough, M Griffith, AC Coffman, AH Wagner, J Kunisaki, ... Nature methods 13 (10), 806-807, 2016 | 62 | 2016 |
| Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer’s disease in multiplex immunoassay panels of cerebrospinal fluid O Harari, C Cruchaga, JSK Kauwe, BJ Ainscough, K Bales, EH Pickering, ... Biological psychiatry 75 (9), 723-731, 2014 | 62 | 2014 |
| The prognostic effects of somatic mutations in ER-positive breast cancer OL Griffith, NC Spies, M Anurag, M Griffith, J Luo, D Tu, B Yeo, J Kunisaki, ... Nature communications 9 (1), 1-16, 2018 | 51 | 2018 |
| Standard operating procedure for somatic variant refinement of sequencing data with paired tumor and normal samples EK Barnell, P Ronning, KM Campbell, K Krysiak, BJ Ainscough, LM Sheta, ... Genetics in Medicine 21 (4), 972-981, 2019 | 33 | 2019 |
| Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B-lymphoblastic leukemia M Griffith, OL Griffith, K Krysiak, ZL Skidmore, MJ Christopher, JM Klco, ... Experimental hematology 44 (7), 603-613, 2016 | 26 | 2016 |
| A deep learning approach to automate refinement of somatic variant calling from cancer sequencing data BJ Ainscough, EK Barnell, P Ronning, KM Campbell, AH Wagner, ... Nature genetics 50 (12), 1735-1743, 2018 | 23 | 2018 |
| Molecular phylogenetics of the burrowing crayfish genus Fallicambarus (Decapoda: Cambaridae) BJ Ainscough, JW Breinholt, HW Robison, KA Crandall Zoologica Scripta 42 (3), 306-316, 2013 | 18 | 2013 |
| CIViC: A knowledgebase for expert-crowdsourcing the clinical interpretation of variants in cancer M Griffith, NC Spies, K Krysiak, AC Coffman, JF McMichael, BJ Ainscough, ... BioRxiv, 072892, 2016 | 7 | 2016 |
| Standard operating procedure for somatic variant refinement of tumor sequencing data EK Barnell, P Ronning, KM Campbell, K Krysiak, BJ Ainscough, ... BioRxiv, 266262, 2018 | 4 | 2018 |
| MyGene. info and MyVariant. info: gene and variant annotation query services J Xin, A Mark, C Afrasiabi, G Tsueng, M Juchler, N Gopal, GS Stupp, ... bioRxiv, 035667, 2015 | 3 | 2015 |
| 26. Community engagement for crowd-sourcing clinically relevant somatic variants, the CIViC experience. K Krysiak, A Danos, A Wagner, J McMichael, A Coffman, S Kiwala, ... Cancer Genetics 244, 10, 2020 | | 2020 |
| 33. Aggregating evidence to determine the clinical significance of cancer variants in the CIViC knowledgebase K Krysiak, A Danos, A Wagner, J McMichael, S Kiwala, A Coffman, ... Cancer Genetics 233, S14, 2019 | | 2019 |
Obi L. GriffithAssociate Professor, Washington University School of MedicineVerified email at wustl.edu
