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Malavika Deodhar
Malavika Deodhar
Scientist II, IGM Biosciences
Verified email at igmbio.com
Title
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Year
Mechanisms of CYP450 inhibition: understanding drug-drug interactions due to mechanism-based inhibition in clinical practice
M Deodhar, SB Al Rihani, MJ Arwood, L Darakjian, P Dow, J Turgeon, ...
Pharmaceutics 12 (9), 846, 2020
1202020
Respiratory dysfunction progresses with age in Kcna1‐null mice, a model of sudden unexpected death in epilepsy
KA Simeone, J Hallgren, CS Bockman, A Aggarwal, V Kansal, L Netzel, ...
Epilepsia 59 (2), 345-357, 2018
522018
Risk assessment of drug‐induced long QT syndrome for some COVID‐19 repurposed drugs
V Michaud, P Dow, SB Al Rihani, M Deodhar, M Arwood, B Cicali, ...
Clinical and Translational Science 14 (1), 20-28, 2021
492021
Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models
S Al Rihani, M Deodhar, LI Darakjian, P Dow, MK Smith, R Bikmetov, ...
Drugs & Aging, 2021
392021
Chronic Inflammatory Status Observed in Patients with Type 2 Diabetes Induces Modulation of Cytochrome P450 Expression and Activity
D Lucy, M Deodhar, J Turgeon, V Michaud
International Journal of Molecular Sciences 22 (9), 2021
382021
Assessing the Mechanism of Fluoxetine-Mediated CYP2D6 Inhibition
M Deodhar, SB Al Rihani, D Lucy, J Turgeon, V Michaud
Pharmaceutics 13 (2:148), 2021
382021
ACE2 as a therapeutic target for COVID-19; its role in infectious processes and regulation by modulators of the RAAS system
V Michaud, M Deodhar, M Arwood, SB Al Rihani, P Dow, J Turgeon
Journal of Clinical Medicine 9 (7), 2096, 2020
362020
Disease-Induced Modulation of Drug Transporters at the Blood-Brain Barrier Level
S Al Rihani, LI Darakjian, M Deodhar, P Dow, J Turgeon, V Michaud
International Journal of Molecular Sciences 22 (7), 2021
282021
Ketogenic diet regulates the antioxidant catalase via the transcription factor PPARγ2
S Knowles, S Budney, M Deodhar, SA Matthews, KA Simeone, ...
Epilepsy research 147, 71-74, 2018
242018
Risk of adverse drug events following the virtual addition of COVID-19 repurposed drugs to drug regimens of frail older adults with polypharmacy
SB Al Rihani, MK Smith, R Bikmetov, M Deodhar, P Dow, J Turgeon, ...
Journal of clinical medicine 9 (8), 2591, 2020
222020
Contribution of CYP2D6 Functional Activity to Oxycodone Efficacy in Pain Management: Genetic Polymorphisms, Phenoconversion, and Tissue-Selective Metabolism
M Deodhar, J Turgeon, V Michaud
Pharmaceutics 13 (9), 2021
202021
Is Dexamethasone a Substrate, an Inducer, or a Substrate-Inducer of CYP3As?
S Al Rihani, M Deodhar, P Dow, J Turgeon, V Michaud
Archives of Pharmacy and Pharmacology Research 2 (5), 2020
152020
Pharmacoresponsiveness of spontaneous recurrent seizures and the comorbid sleep disorder of epileptic Kcna1-null mice
M Deodhar, SA Matthews, B Thomas, L Adamian, S Mattes, T Wells, ...
European journal of pharmacology 913, 174656, 2021
112021
Risk of drug-induced Long QT Syndrome associated with the use of repurposed COVID-19 drugs: A systematic review
V Michaud, P Dow, SBA Rihani, M Deodhar, M Arwood, B Cicali, ...
MedRxiv, 2020.04. 21.20066761, 2020
112020
An Illustrative Case of Phenoconversion due to Multi-Drug Interactions
MV Deodhar Malavika, Dow Pamela, Al Rihani Sweilem B, Turgeon Jacques
Clinical Case Reports Journal 1 (3), 1-6, 2020
82020
Adverse drug event risk assessment by the virtual addition of COVID‐19 repurposed drugs to Medicare and commercially insured patients’ drug regimens: A drug safety simulation study
MK Smith, R Bikmetov, SB Al Rihani, M Deodhar, M Hafermann, P Dow, ...
Clinical and Translational Science 14 (5), 1799-1809, 2021
62021
Mechanisms of CYP450 Inhibition: Understanding Drug-Drug Interactions Due to Mechanism-Based Inhibition in Clinical Practice. Pharmaceutics, 2020, 12 (9), 846
M Deodhar, SB Al Rihani, MJ Arwood, L Darakjian, P Dow, J Turgeon, ...
6
Use of Drug Claims Data and a Medication Risk Score to Assess the Impact of CYP2D6 Drug Interactions among Opioid Users on Healthcare Costs
V Michaud, R Bikmetov, MK Smith, P Dow, LI Darakjian, M Deodhar, ...
Journal of Personalized Medicine, 2021
52021
Assessing the mechanism of fluoxetine-mediated CYP2D6 inhibition. Pharmaceutics 2021; 13: 148
M Deodhar, SBA Rihani, L Darakjian, J Turgeon, V Michaud
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
22021
Development and Characterization of Pre-clinical Epilepsy Models to Evaluate Potential Anti-seizure Targets
M Deodhar
Creighton University, 2019
12019
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Articles 1–20