| Preparative scale resolution of enantiomers enables accelerated drug discovery and development H Leek, S Andersson Molecules 22 (1), 158, 2017 | 59 | 2017 |
| A closer study of methanol adsorption and its impact on solute retentions in supercritical fluid chromatography E Glenne, K Öhlén, H Leek, M Klarqvist, J Samuelsson, T Fornstedt Journal of Chromatography A 1442, 129-139, 2016 | 54 | 2016 |
| Strategy for large-scale isolation of enantiomers in drug discovery H Leek, L Thunberg, AC Jonson, K Öhlén, M Klarqvist Drug Discovery Today 22 (1), 133-139, 2017 | 52 | 2017 |
| Preparative chiral chromatography and chiroptical characterization of enantiomers of omeprazole and related benzimidazoles S Andersson, H Nelander, K Öhlén Chirality: The Pharmacological, Biological, and Chemical Consequences of …, 2007 | 46 | 2007 |
| Evaluation of the chiral recognition properties as well as the column performance of four chiral stationary phases based on cellulose (3, 5-dimethylphenylcarbamate) by parallel … H Nelander, S Andersson, K Öhlén Journal of chromatography A 1218 (52), 9397-9405, 2011 | 38 | 2011 |
| Analytical and preparative separation of phosphorothioated oligonucleotides: columns and ion-pair reagents M Enmark, J Bagge, J Samuelsson, L Thunberg, E Örnskov, H Leek, ... Analytical and bioanalytical chemistry 412, 299-309, 2020 | 36 | 2020 |
| Evaluation of scale-up from analytical to preparative supercritical fluid chromatography M Enmark, D Åsberg, H Leek, K Öhlén, M Klarqvist, J Samuelsson, ... Journal of chromatography A 1425, 280-286, 2015 | 35 | 2015 |
| Potent and orally bioavailable inverse agonists of RORγt resulting from structure-based design F Narjes, Y Xue, S von Berg, J Malmberg, A Llinas, RI Olsson, J Jirholt, ... Journal of Medicinal Chemistry 61 (17), 7796-7813, 2018 | 31 | 2018 |
| Saccharin Aza Bioisosteres Synthesis and Preclinical Property Comparisons Y Chen, CJ Aurell, A Pettersen, RJ Lewis, MA Hayes, M Lepistö, ... ACS Medicinal Chemistry Letters 8 (6), 672-677, 2017 | 27 | 2017 |
| Delivering the promise of SFC: a case study MA Lindskog, H Nelander, AC Jonson, T Halvarsson Drug Discovery Today 19 (10), 1607-1612, 2014 | 22 | 2014 |
| Systematic investigations of peak distortions due to additives in supercritical fluid chromatography E Glenne, J Samuelsson, H Leek, P Forssén, M Klarqvist, T Fornstedt Journal of Chromatography A 1621, 461048, 2020 | 19 | 2020 |
| Peak deformations in preparative supercritical fluid chromatography due to co-solvent adsorption E Glenne, H Leek, M Klarqvist, J Samuelsson, T Fornstedt Journal of Chromatography A 1468, 200-208, 2016 | 19 | 2016 |
| Systematic investigations of peak deformations due to co-solvent adsorption in preparative supercritical fluid chromatography E Glenne, H Leek, M Klarqvist, J Samuelsson, T Fornstedt Journal of Chromatography A 1496, 141-149, 2017 | 18 | 2017 |
| Asymmetric Synthesis of 2,4,5‐Trisubstituted Δ2‐Thiazolines C Bengtsson, H Nelander, F Almqvist Chemistry–A European Journal 19 (30), 9916-9922, 2013 | 18 | 2013 |
| Synthetic and Chromatographic Challenges and Strategies for Multigram Manufacture of KRASG12C Inhibitors G Nikitidis, ACC Carlsson, S Karlsson, AD Campbell, C Cook, K Dai, ... Organic Process Research & Development 26 (3), 710-729, 2021 | 12 | 2021 |
| Chiral Chromatographic Isolation on Milligram Scale of the Human African Trypanosomiasis Treatment d- and l-Eflornithine M Boberg, AC Jonson, H Leek, R Jansson-Löfmark, M Ashton ACS omega 5 (37), 23885-23891, 2020 | 7 | 2020 |
| Unexpected carbonate salt formation during isolation of an enantiopure intermediate by supercritical fluid chromatography L Thunberg, ACC Carlsson, AC Jonson, S Pithani, CJ Aurell, H Leek Journal of Chromatography A 1624, 461172, 2020 | 7 | 2020 |
| Unique photoaffinity probes to study TGFβ signaling and receptor fates D Längle, F Wesseler, D Flötgen, H Leek, AT Plowright, D Schade Chemical communications 55 (30), 4323-4326, 2019 | 5 | 2019 |
| Application of preparative SFC in the pharmaceutical industry J Kingston, H Leek, A Buica, K Öhlén, K Proctor, J Raubo, M Sanders, ... Separation Science and Technology 14, 133-165, 2022 | 4 | 2022 |
