Patrick J. Moynihan
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O-Acetylated peptidoglycan: controlling the activity of bacterial autolysins and lytic enzymes of innate immune systems
PJ Moynihan, AJ Clarke
The international journal of biochemistry & cell biology 43 (12), 1655-1659, 2011
O-acetylation of peptidoglycan in gram-negative bacteria identification and characterization of peptidoglycan o-acetyltransferase in Neisseria gonorrhoeae
PJ Moynihan, AJ Clarke
Journal of Biological Chemistry 285 (17), 13264-13273, 2010
Chemical biology of peptidoglycan acetylation and deacetylation
PJ Moynihan, D Sychantha, AJ Clarke
Bioorganic Chemistry 54, 44-50, 2014
The essential protein for bacterial flagella formation FlgJ functions as a β-N-acetylglucosaminidase
FA Herlihey, PJ Moynihan, AJ Clarke
Journal of biological chemistry 289 (45), 31029-31042, 2014
P. aeruginosa SGNH hydrolase-like proteins AlgJ and AlgX have similar topology but separate and distinct roles in alginate acetylation
P Baker, T Ricer, PJ Moynihan, EN Kitova, MTC Walvoort, DJ Little, ...
PLoS Pathog 10 (8), e1004334, 2014
Identification of KasA as the cellular target of an anti-tubercular scaffold
KA Abrahams, C Chung, S Ghidelli-Disse, J Rullas, MJ Rebollo-López, ...
Nature communications 7 (1), 1-13, 2016
Assay for peptidoglycan O-acetyltransferase: a potential new antibacterial target
PJ Moynihan, AJ Clarke
Analytical biochemistry 439 (2), 73-79, 2013
Two faces of CwlM, an essential PknB substrate, in Mycobacterium tuberculosis
O Turapov, F Forti, B Kadhim, D Ghisotti, J Sassine, ...
Cell reports 25 (1), 57-67. e5, 2018
Substrate specificity and kinetic characterization of peptidoglycan O-acetyltransferase B from Neisseria gonorrhoeae
PJ Moynihan, AJ Clarke
Journal of Biological Chemistry 289 (24), 16748-16760, 2014
Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface
KA Abrahams, JAG Cox, K Fütterer, J Rullas, F Ortega-Muro, NJ Loman, ...
Scientific reports 7 (1), 1-15, 2017
In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA)
D Sychantha, CS Jones, DJ Little, PJ Moynihan, H Robinson, NF Galley, ...
PLoS pathogens 13 (10), e1006667, 2017
Mechanism of Action of Peptidoglycan O-Acetyltransferase B Involves a Ser-His-Asp Catalytic Triad
PJ Moynihan, AJ Clarke
Biochemistry 53 (39), 6243-6251, 2014
Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins
I Tiago, A Maranha, V Mendes, S Alarico, PJ Moynihan, AJ Clarke, ...
Journal of bacteriology 194 (24), 7010-7011, 2012
Bacterial cell wall structure and dynamics
T Dörr, PJ Moynihan, C Mayer
Frontiers in microbiology 10, 2051, 2019
Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides
A Maranha, PJ Moynihan, V Miranda, EC Lourenço, D Nunes-Costa, ...
Scientific reports 5, 13610, 2015
Control of lytic transglycosylase activity within bacterial cell walls
JM Pfeffer, PJ Moynihan, CA Clarke, AJ Clarke
Bacterial glycomics, 55-68, 2012
Nucleotide signaling pathway convergence in a cAMP‐sensing bacterial c‐di‐GMP phosphodiesterase
IT Cadby, SM Basford, R Nottingham, R Meek, R Lowry, C Lambert, ...
The EMBO journal 38 (17), e100772, 2019
Photoactivable glycolipid antigens generate stable conjugates with CD1d for invariant natural killer T cell activation
N Veerapen, SS Kharkwal, P Jervis, V Bhowruth, AK Besra, SJ North, ...
Bioconjugate chemistry 29 (9), 3161-3173, 2018
Identification of KasA as the cellular target of an anti-tubercular scaffold. Nat Commun 7: 12581
KA Abrahams, CW Chung, S Ghidelli-Disse, J Rullas, MJ Rebollo-Lopez, ...
The hydrolase LpqI primes mycobacterial peptidoglycan recycling
PJ Moynihan, IT Cadby, N Veerapen, M Jankute, M Crosatti, ...
Nature communications 10 (1), 2647, 2019
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Articles 1–20