| Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP ML Nelson, HS Kang, GM Lee, AG Blaszczak, DKW Lau, LP McIntosh, ... Proceedings of the National Academy of Sciences 107 (22), 10026-10031, 2010 | 84 | 2010 |
| RPA nucleic acid-binding properties of IFI16-HIN200 H Yan, K Dalal, BK Hon, P Youkharibache, D Lau, F Pio Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (7-8), 1087 …, 2008 | 69 | 2008 |
| Characterizing the N-and C-terminal Small ubiquitin-like modifier (SUMO)-interacting motifs of the scaffold protein DAXX E Escobar-Cabrera, M Okon, DKW Lau, CF Dart, AMJJ Bonvin, ... Journal of Biological Chemistry 286 (22), 19816-19829, 2011 | 53 | 2011 |
| Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer MS Butler, M Roshan-Moniri, M Hsing, D Lau, A Kim, P Yen, M Mroczek, ... Oncotarget 8 (26), 42438, 2017 | 46 | 2017 |
| ETV4 and AP1 transcription factors form multivalent interactions with three sites on the MED25 activator-interacting domain SL Currie, JJ Doane, KS Evans, N Bhachech, BJ Madison, DKW Lau, ... Journal of molecular biology 429 (20), 2975-2995, 2017 | 43 | 2017 |
| Structural characterization of the DAXX N-terminal helical bundle domain and its complex with Rassf1C E Escobar-Cabrera, DKW Lau, S Giovinazzi, AM Ishov, LP McIntosh Structure 18 (12), 1642-1653, 2010 | 38 | 2010 |
| Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5 SL Currie, DKW Lau, JJ Doane, FG Whitby, M Okon, LP McIntosh, ... Nucleic Acids Research 45 (5), 2223-2241, 2017 | 37 | 2017 |
| The PNT domain from Drosophila pointed‐P2 contains a dynamic N‐terminal helix preceded by a disordered phosphoacceptor sequence DKW Lau, M Okon, LP McIntosh Protein Science 21 (11), 1716-1725, 2012 | 12 | 2012 |
| Increasing the therapeutic index of IL12 by engineering for tumor specific protease activation JL Bishop, R Blackler, G Volkers, M Poffenberger, I Yu, J Smith, ... Cancer Research 81 (13_Supplement), 1788-1788, 2021 | 3 | 2021 |
| Design and Selection of IFI16-PAAD Mutants with Improved dsDNA Destabilization Properties D Lau, K Dalal, B Hon, F Pio Journal of Proteomics & Bioinformatics 9 (11), 255-263, 2016 | 2 | 2016 |
| Targeting ETS factor ETV4 as a novel therapeutic for the management of breast and prostate cancer MS Butler, M Hsing, M Roshan Moniri, D Lau, P Yen, A Kim, S Lien, ... Cancer Research 75 (15_Supplement), 1648-1648, 2015 | 1 | 2015 |
| DLL3 TriTCE Co-Stim: A next generation trispecific T cell engager with integrated CD28 costimulation for the treatment of DLL3-expressing cancers P Repenning, D Lau, DC Hernaez, A Robinson, DP Escanda, M Rocha, ... Cancer Research 84 (6_Supplement), 6716-6716, 2024 | | 2024 |
| 1372 TriTCE Co-Stim: a novel trispecific T cell engager platform, with integrated CD28 costimulation, engineered to widen the therapeutic window for treatment of poorly … L Newhook, P Bhojane, P Repenning, D Lau, N Escalante, DP Escanda, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
| ZW270, a conditionally masked IL-12 cytokine fusion protein displaying potent anti-tumor activity absent systemic toxicity MC Poffenberger, JL Bishop, RJ Blackler, KG Haworth, S Booth, ... Cancer Research 83 (7_Supplement), 2935-2935, 2023 | | 2023 |
| STRUCTURED AND DISORDERED REGIONS COOPERATIVELY MEDIATE DNA-BINDING AUTOINHIBITION OF ETS FACTORS ETV1, ETV4, AND ETV5 DK Lau, JJ Doane, FG Whitby, M Okon, LP McIntosh THE STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF ETS TRANSCRIPTION FACTORS …, 2016 | | 2016 |
| Therapeutic targeting of ETS factor ERG for the treatment of prostate cancer M Roshan-Moniri, M Hsing, MS Butler, D Lau, P Axerio-Cilies, P Yen, ... Cancer Research 75 (15_Supplement), 1652-1652, 2015 | | 2015 |
| The replication protein A function of HIN200 family protein is mediated by complementation of PAAD and HIN200 domains DKW Lau Simon Fraser University, 2009 | | 2009 |
| Supplemental Information Structural Characterization of the DAXX N-Terminal Helical Bundle Domain and Its Complex with Rassf1C E Escobar-Cabrera, DKW Lau, S Giovinazzi, AM Ishov, LP McIntosh | | |
