|Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating …|
P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ...
Archives of toxicology 87 (8), 1315-1530, 2013
|A single-cell-based model of tumor growth in vitro: monolayers and spheroids|
D Drasdo, S Hoehme
Physical biology 2 (3), 133, 2005
|Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration|
S Hoehme, M Brulport, A Bauer, E Bedawy, W Schormann, M Hermes, ...
Proceedings of the National Academy of Sciences 107 (23), 10371-10376, 2010
|On the role of physics in the growth and pattern formation of multi-cellular systems: What can we learn from individual-cell based models?|
D Drasdo, S Hoehme, M Block
Journal of Statistical Physics 128 (1-2), 287-345, 2007
|Adverse outcome pathways: opportunities, limitations and open questions|
M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ...
Archives of toxicology 91 (11), 3477-3505, 2017
|Individual-based approaches to birth and death in avascu1ar tumors|
D Drasdo, S Höhme
Mathematical and Computer Modelling 37 (11), 1163-1175, 2003
|A cell-based simulation software for multi-cellular systems|
S Hoehme, D Drasdo
Bioinformatics 26 (20), 2641-2642, 2010
|Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue …|
S Hammad, S Hoehme, A Friebel, I von Recklinghausen, A Othman, ...
Archives of toxicology 88 (5), 1161-1183, 2014
|Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases|
A Ghallab, G Cellière, SG Henkel, D Driesch, S Hoehme, U Hofmann, ...
Journal of hepatology 64 (4), 860-871, 2016
|Integrated metabolic spatial‐temporal model for the prediction of ammonia detoxification during liver damage and regeneration|
F Schliess, S Hoehme, SG Henkel, A Ghallab, D Driesch, J Böttger, ...
Hepatology 60 (6), 2040-2051, 2014
|Mathematical modelling of liver regeneration after intoxication with CCl 4|
S Höhme, JG Hengstler, M Brulport, M Schäfer, A Bauer, R Gebhardt, ...
Chemico-biological interactions 168 (1), 74-93, 2007
|How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis|
D Drasdo, S Hoehme, JG Hengstler
Journal of hepatology 61 (4), 951-956, 2014
|Modeling the impact of granular embedding media, and pulling versus pushing cells on growing cell clones|
D Drasdo, S Hoehme
New Journal of Physics 14 (5), 055025, 2012
|Phenotype and growth behavior of residual β-catenin-positive hepatocytes in livers of β-catenin-deficient mice|
A Braeuning, Y Singh, B Rignall, A Buchmann, S Hammad, A Othman, ...
Histochemistry and cell biology 134 (5), 469-481, 2010
|TiQuant: software for tissue analysis, quantification and surface reconstruction|
A Friebel, J Neitsch, T Johann, S Hammad, JG Hengstler, D Drasdo, ...
Bioinformatics 31 (19), 3234-3236, 2015
|The virtual liver: state of the art and future perspectives|
D Drasdo, J Bode, U Dahmen, O Dirsch, S Dooley, R Gebhardt, A Ghallab, ...
Archives of toxicology 88 (12), 2071-2075, 2014
|Biomechanical and nutrient controls in the growth of mammalian Cell populations|
S Hoehme, D Drasdo
Mathematical Population Studies 17 (3), 166-187, 2010
|Creation of three-dimensional liver tissue models from experimental images for systems medicine|
S Hoehme, A Friebel, S Hammad, D Drasdo, JG Hengstler
Hepatocyte Transplantation, 319-362, 2017
|Unraveling liver complexity from molecular to organ level: Challenges and perspectives|
LA D'Alessandro, S Hoehme, A Henney, D Drasdo, U Klingmüller
Progress in biophysics and molecular biology 117 (1), 78-86, 2015
|Model prediction and validation of an order mechanism controlling the spatiotemporal phenotype of early hepatocellular carcinoma|
S Hoehme, F Bertaux, W Weens, B Grasl-Kraupp, JG Hengstler, D Drasdo
Bulletin of mathematical biology 80 (5), 1134-1171, 2018