| Targeting the MLL complex in castration-resistant prostate cancer R Malik, AP Khan, IA Asangani, M Cieślik, JR Prensner, X Wang, MK Iyer, ... Nature medicine 21 (4), 344-352, 2015 | 198 | 2015 |
| BET bromodomain inhibitors enhance efficacy and disrupt resistance to AR antagonists in the treatment of prostate cancer IA Asangani, K Wilder-Romans, VL Dommeti, PM Krishnamurthy, IJ Apel, ... Molecular Cancer Research 14 (4), 324-331, 2016 | 170 | 2016 |
| KRAS protein stability is regulated through SMURF2: UBCH5 complex-mediated β-TrCP1 degradation S Shukla, US Allam, A Ahsan, G Chen, PM Krishnamurthy, K Marsh, ... Neoplasia 16 (2), 115-W5, 2014 | 92 | 2014 |
| EWS/ETS-driven ewing sarcoma requires BET bromodomain proteins PN Gollavilli, A Pawar, K Wilder-Romans, R Natesan, CG Engelke, ... Cancer research 78 (16), 4760-4773, 2018 | 60 | 2018 |
| 5′ Modifications improve potency and efficacy of DNA donors for precision genome editing KS Ghanta, GA Dokshin, A Mir, PM Krishnamurthy, H Gneid, A Edraki, ... BioRxiv, 354480, 2018 | 46 | 2018 |
| Synthesis and biological properties of triazole-linked locked nucleic acid VK Sharma, SK Singh, PM Krishnamurthy, JF Alterman, RA Haraszti, ... Chemical communications 53 (63), 8906-8909, 2017 | 36 | 2017 |
| Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA JKW Hannah M. Pendergraff, Pranathi Meda Krishnamurthy, Alexandre J ... Molecular Therapy 159, 2017 | 25* | 2017 |
| Tristetraprolin mediates radiation-induced TNF-α production in lung macrophages D Ray, S Shukla, US Allam, A Helman, SG Ramanand, L Tran, M Bassetti, ... PloS one 8 (2), e57290, 2013 | 19 | 2013 |
| Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts M Shin, IL Chan, Y Cao, AM Gruntman, J Lee, J Sousa, TC Rodríguez, ... Nucleic Acids Research 50 (15), 8418-8430, 2022 | 15 | 2022 |
| Quantification of antisense oligonucleotides by splint ligation and quantitative polymerase chain reaction M Shin, P Meda Krishnamurthy, G Devi, JK Watts nucleic acid therapeutics 32 (1), 66-73, 2022 | 15 | 2022 |
| Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection VN Hariharan, M Shin, CW Chang, D O’Reilly, A Biscans, K Yamada, ... Proceedings of the National Academy of Sciences 120 (11), e2219523120, 2023 | 14 | 2023 |
| Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis PM Krishnamurthy, S Shukla, P Ray, R Mehra, MK Nyati, TS Lawrence, ... Oncotarget 8 (29), 47767, 2017 | 13 | 2017 |
| Quantifying and mitigating motor phenotypes induced by antisense oligonucleotides in the central nervous system MP Moazami, JM Rembetsy-Brown, F Wang, PM Krishnamurthy, A Weiss, ... BioRxiv, 2021.02. 14.431096, 2021 | 12 | 2021 |
| Next-generation PNA chimeras exhibit high affinity and potent gene silencing JW Alexandre J Debacker, Vivek K. Sharma, Pranathi Meda Krishnamurthy ... Biochemistry, 2019 | 12* | 2019 |
| CASCADES, a novel SOX2 super-enhancer associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma multiforme biorxiv, 2020 | 2 | 2020 |
| OLIGONUCLEOTIDES FOR SARS-CoV-2 MODULATION A Khvorova, J Watts, Z Kennedy, A Biscans, BM da Cruz Godinho, ... US Patent App. 17/333,839, 2023 | 1 | 2023 |
| EZH2 inhibition reactivates epigenetically silenced FMR1 and normalizes molecular and electrophysiological abnormalities in fragile X syndrome neurons M Fang, SK Deibler, PM Krishnamurthy, F Wang, P Rodriguez, S Banday, ... Frontiers in Neuroscience 18, 1348478, 2024 | | 2024 |
| A combinatorial approach for achieving CNS-selective RNAi CM Ferguson, BMDC Godinho, D Echeverria, M Hassler, L Vangjeli, ... Nucleic Acids Research, gkae100, 2024 | | 2024 |
| G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects F Wang, E Calvo-Roitberg, JM Rembetsy-Brown, M Fang, J Sousa, ... Nucleic Acids Research 50 (22), 12657-12673, 2022 | | 2022 |
| Quantification of Antisense Oligonucleotides by Splint Ligation and Quantitative Polymerase Chain Reaction [preprint] M Shin, PM Krishnamurthy, JK Watts | | 2021 |
