Pia Abel zur Wiesch
Pia Abel zur Wiesch
Associate Professor/ Early Career Chair, Penn State University
Verified email at - Homepage
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Antagonism between bacteriostatic and bactericidal antibiotics is prevalent
PS Ocampo, V Lázár, B Papp, M Arnoldini, P Abel zur Wiesch, ...
Antimicrobial agents and chemotherapy 58 (8), 4573-4582, 2014
Population biological principles of drug-resistance evolution in infectious diseases
PA Zur Wiesch, R Kouyos, J Engelstädter, RR Regoes, S Bonhoeffer
The Lancet infectious diseases 11 (3), 236-247, 2011
Compensation of fitness costs and reversibility of antibiotic resistance mutations
P Schulz zur Wiesch, J Engelstadter, S Bonhoeffer
Antimicrobial agents and chemotherapy 54 (5), 2085-2095, 2010
Bi-modal Distribution of the Second Messenger c-di-GMP Controls Cell Fate and Asymmetry during the Caulobacter Cell Cycle
S Abel, T Bucher, M Nicollier, I Hug, V Kaever, P Abel zur Wiesch, U Jenal
PLoS genetics 9 (9), e1003744, 2013
Analysis of bottlenecks in experimental models of infection
S Abel, P Abel zur Wiesch, BM Davis, MK Waldor
PLoS pathogens 11 (6), e1004823, 2015
Genetic analysis of Vibrio parahaemolyticus intestinal colonization
TP Hubbard, MC Chao, S Abel, CJ Blondel, P Abel zur Wiesch, X Zhou, ...
Proceedings of the National Academy of Sciences 113 (22), 6283-6288, 2016
The path of least resistance: aggressive or moderate treatment?
RD Kouyos, CJE Metcalf, R Birger, EY Klein, P Abel zur Wiesch, ...
Proceedings of the Royal Society B: Biological Sciences 281 (1794), 20140566, 2014
Cycling empirical antibiotic therapy in hospitals: meta-analysis and models
P Abel zur Wiesch, R Kouyos, S Abel, W Viechtbauer, S Bonhoeffer
PLoS pathogens 10 (6), e1004225, 2014
Sequence tag–based analysis of microbial population dynamics
S Abel, P Abel zur Wiesch, HH Chang, BM Davis, M Lipsitch, MK Waldor
Nature methods 12 (3), 223-226, 2015
Smear positivity in paediatric and adult tuberculosis: systematic review and meta-analysis
A Kunkel, P Abel zur Wiesch, RR Nathavitharana, FM Marx, HE Jenkins, ...
BMC infectious diseases 16, 1-9, 2016
Classic reaction kinetics can explain complex patterns of antibiotic action
P Abel Zur Wiesch, S Abel, S Gkotzis, P Ocampo, J Engelstädter, ...
Science translational medicine 7 (287), 287ra73-287ra73, 2015
Deciphering the landscape of host barriers to Listeria monocytogenes infection
T Zhang, S Abel, P Abel zur Wiesch, J Sasabe, BM Davis, DE Higgins, ...
Proceedings of the National Academy of Sciences 114 (24), 6334-6339, 2017
On being the right size: the impact of population size and stochastic effects on the evolution of drug resistance in hospitals and the community
RD Kouyos, P Abel zur Wiesch, S Bonhoeffer
PLoS pathogens 7 (4), e1001334, 2011
Informed switching strongly decreases the prevalence of antibiotic resistance in hospital wards
RD Kouyos, P Abel zur Wiesch, S Bonhoeffer
PLoS computational biology 7 (3), e1001094, 2011
Fitness Costs of Drug Resistance Mutations in Multidrug-Resistant Mycobacterium tuberculosis: A Household-Based Case-Control Study
PP Salvatore, MC Becerra, P Abel zur Wiesch, T Hinkley, D Kaur, ...
The Journal of infectious diseases 213 (1), 149-155, 2016
Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization
AR Warr, TP Hubbard, D Munera, CJ Blondel, P Abel zur Wiesch, S Abel, ...
PLoS pathogens 15 (8), e1007652, 2019
The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB
D Cadosch, P Abel zur Wiesch, R Kouyos, S Bonhoeffer
PLoS computational biology 12 (3), e1004749, 2016
Using chemical reaction kinetics to predict optimal antibiotic treatment strategies
P Abel zur Wiesch, F Clarelli, T Cohen
PLoS computational biology 13 (1), e1005321, 2017
Quantifying the impact of treatment history on plasmid-mediated resistance evolution in human gut microbiota
B Tepekule, P Abel zur Wiesch, RD Kouyos, S Bonhoeffer
Proceedings of the National Academy of Sciences 116 (46), 23106-23116, 2019
Multi-scale modeling of drug binding kinetics to predict drug efficacy
F Clarelli, J Liang, A Martinecz, I Heiland, P Abel zur Wiesch
Cellular and Molecular Life Sciences 77, 381-394, 2020
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