David Scadden
David Scadden
Verified email at mgh.harvard.edu - Homepage
TitleCited byYear
Osteoblastic cells regulate the haematopoietic stem cell niche
LM Calvi, GB Adams, KW Weibrecht, JM Weber, DP Olson, MC Knight, ...
Nature 425 (6960), 841-846, 2003
36012003
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
S Méndez-Ferrer, TV Michurina, F Ferraro, AR Mazloom, BD MacArthur, ...
Nature 466 (7308), 829-834, 2010
25252010
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
CG Willett, Y Boucher, E Di Tomaso, DG Duda, LL Munn, RT Tong, ...
Nature medicine 10 (2), 145-147, 2004
21912004
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
CG Willett, Y Boucher, E Di Tomaso, DG Duda, LL Munn, RT Tong, ...
Nature medicine 10 (2), 145-147, 2004
21792004
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
M Lewin, N Carlesso, CH Tung, XW Tang, D Cory, DT Scadden, ...
Nature biotechnology 18 (4), 410-414, 2000
20872000
The stem-cell niche as an entity of action
DT Scadden
Nature 441 (7097), 1075-1079, 2006
19032006
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
TT Batchelor, AG Sorensen, E di Tomaso, WT Zhang, DG Duda, ...
Cancer cell 11 (1), 83-95, 2007
17832007
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
T Cheng, N Rodrigues, H Shen, Y Yang, D Dombkowski, M Sykes, ...
Science 287 (5459), 1804-1808, 2000
13972000
The bone marrow niche for haematopoietic stem cells
SJ Morrison, DT Scadden
Nature 505 (7483), 327-334, 2014
13412014
Biology of hematopoietic stem cells and progenitors: implications for clinical application
M Kondo, AJ Wagers, MG Manz, SS Prohaska, DC Scherer, GF Beilhack, ...
Annual review of immunology 21 (1), 759-806, 2003
11502003
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16 INK4a
V Janzen, R Forkert, HE Fleming, Y Saito, MT Waring, DM Dombkowski, ...
Nature 443 (7110), 421-426, 2006
10722006
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
MHGP Raaijmakers, S Mukherjee, S Guo, S Zhang, T Kobayashi, ...
Nature 464 (7290), 852-857, 2010
9042010
In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment
DA Sipkins, X Wei, JW Wu, JM Runnels, D Côté, TK Means, AD Luster, ...
Nature 435 (7044), 969-973, 2005
8512005
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation
KW Orford, DT Scadden
Nature Reviews Genetics 9 (2), 115-128, 2008
8042008
A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection
LM Albritton, L Tseng, D Scadden, JM Cunningham
Cell 57 (4), 659-666, 1989
7901989
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
CL Celso, HE Fleming, JW Wu, CX Zhao, S Miake-Lye, J Fujisaki, D Côté, ...
Nature 457 (7225), 92-96, 2009
7822009
Oocyte generation in adult mammalian ovaries by putative germ cells in bone marrow and peripheral blood
J Johnson, J Bagley, M Skaznik-Wikiel, HJ Lee, GB Adams, Y Niikura, ...
Cell 122 (2), 303-315, 2005
7572005
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor
GB Adams, KT Chabner, IR Alley, DP Olson, ZM Szczepiorkowski, ...
Nature 439 (7076), 599, 2006
7502006
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
S Stier, Y Ko, R Forkert, C Lutz, T Neuhaus, E Grünewald, T Cheng, ...
The Journal of experimental medicine 201 (11), 1781-1791, 2005
6532005
Bayesian approach to single-cell differential expression analysis
PV Kharchenko, L Silberstein, DT Scadden
Nature methods 11 (7), 740, 2014
6312014
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Articles 1–20