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Peter Siegel
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Genes that mediate breast cancer metastasis to lung
AJ Minn, GP Gupta, PM Siegel, PD Bos, W Shu, DD Giri, A Viale, ...
Nature 436 (7050), 518-524, 2005
34482005
A multigenic program mediating breast cancer metastasis to bone
Y Kang, PM Siegel, W Shu, M Drobnjak, SM Kakonen, C Cordón-Cardo, ...
Cancer cell 3 (6), 537-549, 2003
31092003
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ...
Nature 482 (7384), 226-231, 2012
25842012
Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer
PM Siegel, J Massagué
Nature Reviews Cancer 3 (11), 807-820, 2003
21272003
AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo
B Faubert, G Boily, S Izreig, T Griss, B Samborska, Z Dong, F Dupuy, ...
Cell metabolism 17 (1), 113-124, 2013
9532013
E2F4/5 and p107 as Smad cofactors linking the TGFβ receptor to c-myc repression
CR Chen, Y Kang, PM Siegel, J Massagué
Cell 110 (1), 19-32, 2002
6582002
Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer
PM Siegel, ED Ryan, RD Cardiff, WJ Muller
The EMBO journal 18 (8), 2149-2164, 1999
6111999
Transforming growth factor β signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis
PM Siegel, W Shu, RD Cardiff, WJ Muller, J Massagué
Proceedings of the National Academy of Sciences 100 (14), 8430-8435, 2003
5502003
PDK1-dependent metabolic reprogramming dictates metastatic potential in breast cancer
F Dupuy, S Tabariès, S Andrzejewski, Z Dong, J Blagih, MG Annis, ...
Cell metabolism 22 (4), 577-589, 2015
5112015
Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
XY Liu, N Gerges, A Korshunov, N Sabha, DA Khuong-Quang, ...
Acta neuropathologica 124, 615-625, 2012
4932012
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma
AM Fontebasso, S Papillon-Cavanagh, J Schwartzentruber, H Nikbakht, ...
Nature genetics 46 (5), 462-466, 2014
4372014
Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway
RJ Lee, C Albanese, M Fu, M D'Amico, B Lin, G Watanabe, GK Haines III, ...
Molecular and cellular biology 20 (2), 672-683, 2000
4252000
Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations
M Dankner, AAN Rose, S Rajkumar, PM Siegel, IR Watson
Oncogene 37 (24), 3183-3199, 2018
3812018
Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis
ER Andrechek, WR Hardy, PM Siegel, MA Rudnicki, RD Cardiff, ...
Proceedings of the National Academy of Sciences 97 (7), 3444-3449, 2000
3162000
Novel Activating Mutations in the neu Proto-oncogene Involved in Induction of Mammary Tumors
PM Siegel, DL Dankort, WR Hardy, WJ Muller
Molecular and cellular biology 14 (11), 7068-7077, 1994
3031994
Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity
SK Muthuswamy, PM Siegel, DL Dankort, MA Webster, WJ Muller
Molecular and cellular biology 14 (1), 735-743, 1994
3031994
Reciprocal regulation of Neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo: implications for human breast cancer
JA Engelman, RJ Lee, A Karnezis, DJ Bearss, M Webster, P Siegel, ...
Journal of Biological Chemistry 273 (32), 20448-20455, 1998
2811998
Metabolic plasticity as a determinant of tumor growth and metastasis
C Lehuédé, F Dupuy, R Rabinovitch, RG Jones, PM Siegel
Cancer research 76 (18), 5201-5208, 2016
2672016
PGC-1α promotes breast cancer metastasis and confers bioenergetic flexibility against metabolic drugs
S Andrzejewski, E Klimcakova, RM Johnson, S Tabariès, MG Annis, ...
Cell metabolism 26 (5), 778-787. e5, 2017
2302017
ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties
AAN Rose, MG Annis, Z Dong, F Pepin, M Hallett, M Park, PM Siegel
PloS one 5 (8), e12093, 2010
2162010
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