Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7) C Simhadri, KD Daze, SF Douglas, TTH Quon, A Dev, MC Gignac, F Peng, ... Journal of medicinal chemistry 57 (7), 2874-2883, 2014 | 116 | 2014 |
A broadly applicable cross-linker for aliphatic polymers containing C–H bonds ML Lepage, C Simhadri, C Liu, M Takaffoli, L Bi, B Crawford, AS Milani, ... Science 366 (6467), 875-878, 2019 | 110 | 2019 |
Selective inhibition of CBX6: a methyllysine reader protein in the polycomb family N Milosevich, MC Gignac, J McFarlane, C Simhadri, S Horvath, KD Daze, ... ACS Medicinal Chemistry Letters 7 (2), 139-144, 2016 | 56 | 2016 |
Flexible polyfluorinated bis-diazirines as molecular adhesives C Simhadri, L Bi, ML Lepage, M Takaffoli, Z Pei, SF Musolino, AS Milani, ... Chemical Science 12 (11), 4147-4153, 2021 | 29 | 2021 |
Structure–activity relationships of Cbx7 inhibitors, including selectivity studies against other Cbx proteins C Simhadri, MC Gignac, CJ Anderson, N Milosevich, A Dheri, N Prashar, ... ACS omega 1 (4), 541-551, 2016 | 18 | 2016 |
Dissecting the complex recognition interfaces of potent tetrazole-and pyrrole-based anion binders T Pinter, C Simhadri, F Hof The Journal of Organic Chemistry 78 (10), 4642-4648, 2013 | 18 | 2013 |
Influence of topical cross-linking on mechanical and ballistic performance of a woven ultra-high-molecular-weight polyethylene fabric used in soft body armor ML Lepage, M Takaffoli, C Simhadri, R Mandau, MP Gashti, R Nazir, ... ACS Applied Polymer Materials 3 (11), 6008-6018, 2021 | 9 | 2021 |
Rational Adaptation of L3MBTL1 Inhibitors to Create Small‐Molecule Cbx7 Antagonists C Simhadri, KD Daze, SF Douglas, N Milosevich, L Monjas, A Dev, ... ChemMedChem 14 (15), 1444-1456, 2019 | 7 | 2019 |
Efficient purification of the diarylheptanoid oregonin from red alder (Alnus rubra) leaves and bark combining aqueous extraction, spray drying and flash … CS Lea, C Simhadri, SG Bradbury, JE Wulff, CP Constabel Phytochemical Analysis 32 (4), 554-561, 2021 | 5 | 2021 |
Diazirine-based molecules and uses thereof JE Wulff, PG Berrang, ML Lepage, C Simhadri US Patent App. 17/606,649, 2022 | | 2022 |
Design, synthesis, and evaluation of polycomb reader protein Cbx7 antagonists C Simhadri | | 2017 |