| Mre11/Rad50/Nbs1: Complex activities N Assenmacher, KP Hopfner Chromosoma 113, 157-166, 2004 | 206 | 2004 |
| Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients D Fey, M Halasz, D Dreidax, SP Kennedy, JF Hastings, N Rauch, ... Science signaling 8 (408), ra130-ra130, 2015 | 160 | 2015 |
| MAPK kinase signalling dynamics regulate cell fate decisions and drug resistance N Rauch, OS Rukhlenko, W Kolch, BN Kholodenko Current opinion in structural biology 41, 151-158, 2016 | 96 | 2016 |
| Substrate-trapped interactors of PHD3 and FIH cluster in distinct signaling pathways J Rodriguez, R Pilkington, AG Munoz, LK Nguyen, N Rauch, S Kennedy, ... Cell reports 14 (11), 2745-2760, 2016 | 95 | 2016 |
| PHD3 regulates p53 protein stability by hydroxylating proline 359 J Rodriguez, A Herrero, S Li, N Rauch, A Quintanilla, K Wynne, A Krstic, ... Cell reports 24 (5), 1316-1329, 2018 | 65 | 2018 |
| Dissecting RAF inhibitor resistance by structure-based modeling reveals ways to overcome oncogenic RAS signaling OS Rukhlenko, F Khorsand, A Krstic, J Rozanc, LG Alexopoulos, N Rauch, ... Cell systems 7 (2), 161-179. e14, 2018 | 58* | 2018 |
| Phosphorylation of RAF kinase dimers drives conformational changes that facilitate transactivation PG Jambrina, N Rauch, R Pilkington, K Rybakova, LK Nguyen, ... Angewandte Chemie 128 (3), 995-998, 2016 | 52 | 2016 |
| Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D SA Kennedy, MA Jarboui, S Srihari, C Raso, K Bryan, L Dernayka, ... Nature communications 11 (1), 499, 2020 | 51 | 2020 |
| Structural basis for transcription-coupled repair: the N terminus of Mfd resembles UvrB with degenerate ATPase motifs N Assenmacher, K Wenig, A Lammens, KP Hopfner Journal of molecular biology 355 (4), 675-683, 2006 | 41 | 2006 |
| Control of cell state transitions OS Rukhlenko, M Halasz, N Rauch, V Zhernovkov, T Prince, K Wynne, ... Nature 609 (7929), 975-985, 2022 | 36 | 2022 |
| A novel RNA sequencing data analysis method for cell line authentication E Fasterius, C Raso, S Kennedy, N Rauch, P Lundin, W Kolch, M Uhlen, ... PloS one 12 (2), e0171435, 2017 | 32 | 2017 |
| A systematic analysis of signaling reactivation and drug resistance BN Kholodenko, N Rauch, W Kolch, OS Rukhlenko Cell reports 35 (8), 2021 | 17 | 2021 |
| Metabolic stress regulates ERK activity by controlling KSR‐RAF heterodimerization A Verlande, M Krafčíková, D Potěšil, L Trantírek, Z Zdráhal, M Elkalaf, ... EMBO reports 19 (2), 320-336, 2018 | 13 | 2018 |
| Stabilization of C-RAF: KSR1 complex by DiRas3 reduces availability of C-RAF for dimerization with B-RAF A Baljuls, M Dobrzyński, J Rauch, N Rauch, W Kolch Cellular Signalling 28 (10), 1451-1462, 2016 | 7 | 2016 |
| Autophosphorylation on S614 inhibits the activity and the transforming potential of BRAF L Dernayka, N Rauch, MA Jarboui, A Zebisch, Y Texier, N Horn, ... Cellular Signalling 28 (9), 1432-1439, 2016 | 5 | 2016 |
| Interactome dynamics of RAF1-BRAF kinase monomers and dimers LF Iglesias-Martinez, N Rauch, K Wynne, B McCann, W Kolch, J Rauch Scientific Data 10 (1), 203, 2023 | 4 | 2023 |
| Structural and biochemical analysis of the UvrA binding module of the bacterial transcription repair coupling factor Mfd N Aßenmacher lmu, 2006 | 2 | 2006 |
| A combination of conformation-specific RAF inhibitors overcome drug resistance brought about by RAF overexpression H Imoto, N Rauch, AJ Neve, F Khorsand, M Kreileder, LG Alexopoulos, ... Biomolecules 13 (8), 1212, 2023 | 1 | 2023 |
| Kinase Suppressor of RAS 1 (KSR1) maintains the transformed phenotype of BRAFV600E mutant human melanoma cells Z Liu, A Krstic, A Neve, C Casalou, N Rauch, K Wynne, H Cassidy, ... International Journal of Molecular Sciences 24 (14), 11821, 2023 | | 2023 |
| Abstract CN05-03: Personalized cancer diagnostics and therapeutics based on the computational modeling of signal transduction networks W Kolch, D Fey, M Halasz, N Rauch, AG Munoz, R Pilkington, ... Molecular Cancer Therapeutics 14 (12_Supplement_2), CN05-03-CN05-03, 2015 | | 2015 |
