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Mark Adrian Brooks
Mark Adrian Brooks
Project Leader, Evotec
Adresse e-mail validée de evotec.com
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Binding mode and structure–activity relationships around direct inhibitors of the Nrf2–Keap1 complex
E Jnoff, C Albrecht, JJ Barker, O Barker, E Beaumont, S Bromidge, ...
ChemMedChem 9 (4), 699-705, 2014
1412014
Discovery and structure–activity relationship of potent and selective covalent inhibitors of transglutaminase 2 for Huntington’s disease
ME Prime, OA Andersen, JJ Barker, MA Brooks, RKY Cheng, ...
Journal of medicinal chemistry 55 (3), 1021-1046, 2012
862012
Structure–function analysis of pneumococcal DprA protein reveals that dimerization is crucial for loading RecA recombinase onto DNA during transformation
S Quevillon-Cheruel, N Campo, N Mirouze, I Mortier-Barrière, MA Brooks, ...
Proceedings of the National Academy of Sciences 109 (37), E2466-E2475, 2012
712012
Structure of the yeast Pml1 splicing factor and its integration into the RES complex
MA Brooks, A Dziembowski, S Quevillon-Cheruel, V Henriot, C Faux, ...
Nucleic acids research 37 (1), 129-143, 2009
432009
Synthesis, structure and cytotoxicity of cyclic (alkyl)(amino) carbene and acyclic carbene complexes of group 11 metals
B Bertrand, AS Romanov, M Brooks, J Davis, C Schmidt, I Ott, ...
Dalton Transactions 46 (45), 15875-15887, 2017
402017
The structure of an archaeal homodimeric ligase which has RNA circularization activity
MA Brooks, L Meslet‐Cladiére, M Graille, J Kuhn, K Blondeau, ...
Protein Science 17 (8), 1336-1345, 2008
362008
The carboxy-terminal αN helix of the archaeal XerA tyrosine recombinase is a molecular switch to control site-specific recombination
MC Serre, T El Arnaout, MA Brooks, D Durand, J Lisboa, N Lazar, ...
PLoS One 8 (5), e63010, 2013
262013
X-Ray Structure and Site-Directed Mutagenesis Analysis of the Escherichia coli Colicin M Immunity Protein
F Gérard, MA Brooks, H Barreteau, T Touzé, M Graille, A Bouhss, ...
Journal of bacteriology 193 (1), 205-214, 2011
252011
Characterization of colicin M and its orthologs targeting bacterial cell wall peptidoglycan biosynthesis
H Barreteau, M El Ghachi, A Barnéoud-Arnoulet, E Sacco, T Touzé, ...
Microbial Drug Resistance 18 (3), 222-229, 2012
222012
Determinants of potassium channel assembly localised within the cytoplasmic C-terminal domain of Kv2. 1
GN Bentley, MA Brooks, CA O’Neill, JBC Findlay
Biochimica et Biophysica Acta (BBA)-Biomembranes 1418 (1), 176-184, 1999
201999
A novel protein-protein interaction in the RES (REtention and Splicing) complex
K Tripsianes, A Friberg, C Barrandon, M Brooks, H van Tilbeurgh, ...
Journal of Biological Chemistry 289 (41), 28640-28650, 2014
192014
Strategies for the structural analysis of multi-protein complexes: lessons from the 3D-Repertoire project
B Collinet, A Friberg, MA Brooks, T van den Elzen, V Henriot, ...
Journal of Structural Biology 175 (2), 147-158, 2011
192011
Crystal structure of a signal recognition particle Alu domain in the elongation arrest conformation
L Bousset, C Mary, MA Brooks, A Scherrer, K Strub, S Cusack
Rna 20 (12), 1955-1962, 2014
112014
Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations
MA Brooks, K Gewartowski, E Mitsiki, J Létoquart, RA Pache, Y Billier, ...
Structure 18 (9), 1075-1082, 2010
102010
Structure of SRP14 from the Schizosaccharomyces pombe signal recognition particle
MA Brooks, RBG Ravelli, AA McCarthy, K Strub, S Cusack
Acta Crystallographica Section D: Biological Crystallography 65 (5), 421-433, 2009
92009
Expression, purification and preliminary structural analysis of Escherichia coli MatP in complex with the matS DNA site
D Durand, I Li de la Sierra-Gallay, MA Brooks, AW Thompson, N Lazar, ...
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012
42012
Inside Cover: Binding Mode and Structure–Activity Relationships around Direct Inhibitors of the Nrf2–Keap1 Complex (ChemMedChem 4/2014)
E Jnoff, C Albrecht, JJ Barker, O Barker, E Beaumont, S Bromidge, ...
ChemMedChem 9 (4), 674-674, 2014
12014
Crystal structure of a signal recognition particle
L Bousset, C Mary, MA Brooks
2014
Correction: The Carboxy-Terminal αN Helix of the Archaeal XerA Tyrosine Recombinase Is a Molecular Switch to Control Site-Specific Recombination
MC Serre, T El Arnaout, MA Brooks, D Durand, J Lisboa, N Lazar, ...
Plos one 9 (1), 2014
2014
Référentiel des projets ANR: import des projets PIA gérés par l'Agence (Idex, labex) de 2011 à 2017 (25/06/2019)
K Tripsianes, A Friberg, C Barrandon, M Brooks, H van Tilbeurgh
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