Suivre
seyed-omar zaraei
seyed-omar zaraei
Scientific Assistant, HIPS, UdS
Adresse e-mail validée de helmholtz-hips.de
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Année
A review of HER4 (ErbB4) kinase, its impact on cancer, and its inhibitors
MI El-Gamal, NH Mewafi, NE Abdelmotteleb, MA Emara, H Tarazi, ...
Molecules 26 (23), 7376, 2021
372021
Evaluation of substituted pyrazole-based kinase inhibitors in one decade (2011–2020): Current status and future prospects
MI El-Gamal, SO Zaraei, MM Madkour, HS Anbar
Molecules 27 (1), 330, 2022
242022
Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase
MI El-Gamal, S Ullah, SO Zaraei, S Jalil, S Zaib, DM Zaher, HA Omar, ...
European Journal of Medicinal Chemistry 181, 111560, 2019
242019
Sulfamates in drug design and discovery: pre-clinical and clinical investigations
SO Zaraei, AR Abduelkarem, HS Anbar, S Kobeissi, M Mohammad, ...
European Journal of Medicinal Chemistry 179, 257-271, 2019
242019
Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase
S Ullah, MI El-Gamal, S Zaib, HS Anbar, SO Zaraei, RM Sbenati, ...
Bioorganic Chemistry 99, 103783, 2020
212020
A new series of aryl sulfamate derivatives: design, synthesis, and biological evaluation
MI El-Gamal, SO Zaraei, PA Foster, HS Anbar, R El-Gamal, R El-Awady, ...
Bioorganic & Medicinal Chemistry 28 (8), 115406, 2020
192020
Discovery of urease inhibitory effect of sulfamate derivatives: Biological and computational studies
S Zaib, MT Younas, SO Zaraei, I Khan, HS Anbar, MI El-Gamal
Bioorganic Chemistry 119, 105545, 2022
182022
Discovery of first-in-class imidazothiazole-based potent and selective ErbB4 (HER4) kinase inhibitors
SO Zaraei, RM Sbenati, NN Alach, HS Anbar, R El-Gamal, H Tarazi, ...
European Journal of Medicinal Chemistry 224, 113674, 2021
172021
Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl) pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors
EMH Ali, RFA El-Telbany, MS Abdel-Maksoud, UM Ammar, KI Mersal, ...
European Journal of Medicinal Chemistry 215, 113277, 2021
172021
Design, synthesis, biological evaluation, and modeling studies of novel conformationally-restricted analogues of sorafenib as selective kinase-inhibitory antiproliferative …
RM Sbenati, SO Zaraei, MI El-Gamal, HS Anbar, H Tarazi, MM Zoghbor, ...
European journal of medicinal chemistry 210, 113081, 2021
132021
Evaluation of sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as inhibitors of nucleotide pyrophosphatases/phosphodiesterases and anticancer …
HS Anbar, R El-Gamal, S Ullah, SO Zaraei, M Al-Rashida, S Zaib, ...
Bioorganic Chemistry 104, 104305, 2020
122020
Design and synthesis of new quinoline derivatives as selective C-RAF kinase inhibitors with potent anticancer activity
SO Zaraei, NN Al-Ach, HS Anbar, R El-Gamal, H Tarazi, RT Tokatly, ...
European Journal of Medicinal Chemistry 238, 114434, 2022
102022
Sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as potent carbonic anhydrase II/IX/XII inhibitors
SO Zaraei, MI El-Gamal, Z Shafique, ST Amjad, S Afridi, S Zaib, HS Anbar, ...
Bioorganic & Medicinal Chemistry 27 (17), 3889-3901, 2019
102019
Diarylamides in anticancer drug discovery: A review of pre-clinical and clinical investigations
AR Abduelkarem, HS Anbar, SO Zaraei, AA Alfar, OS Al-Zoubi, ...
European Journal of Medicinal Chemistry 188, 112029, 2020
92020
Design and synthesis of new adamantyl derivatives as promising antiproliferative agents
AI Shahin, SO Zaraei, BO AlKubaisi, S Ullah, HS Anbar, R El-Gamal, ...
European Journal of Medicinal Chemistry 246, 114958, 2023
72023
Design, synthesis, and biological evaluation of a new series of pyrazole derivatives: Discovery of potent and selective JNK3 kinase inhibitors
RRA Rabah, A Sebastian, S Vunnam, S Sultan, H Tarazi, HS Anbar, ...
Bioorganic & Medicinal Chemistry 69, 116894, 2022
72022
Structural optimization of 4-(imidazol-5-yl) pyridine derivatives affords broad-spectrum anticancer agents with selective B-RAFV600E/p38α kinase inhibitory activity: synthesis …
EMH Ali, KI Mersal, UM Ammar, SO Zaraei, MS Abdel-Maksoud, ...
European Journal of Pharmaceutical Sciences 171, 106115, 2022
52022
Design and synthesis of novel anti-urease imidazothiazole derivatives with promising antibacterial activity against Helicobacter pylori
AI Shahin, S Zaib, SO Zaraei, RA Kedia, HS Anbar, MT Younas, TH Al-Tel, ...
Plos one 18 (6), e0286684, 2023
42023
Novel anti-acanthamoebic activities of Irosustat and STX140 and their nanoformulations
R Siddiqui, M Rawas-Qalaji, MI El-Gamal, S Sajeev, J Jagal, SO Zaraei, ...
Antibiotics 12 (3), 561, 2023
32023
Synthesis and biological evaluation of sulfamate derivatives as inhibitors of carbonic anhydrases II and IX
S Jalil, S Ullah, SO Zaraei, RM Sbenati, AI Shahin, BO AlKubaisi, ...
Medicinal Chemistry Research 32 (5), 869-883, 2023
22023
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