| MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells JA Chan, AM Krichevsky, KS Kosik Cancer research 65 (14), 6029-6033, 2005 | 3404 | 2005 |
| Gene regulation and DNA damage in the ageing human brain T Lu, Y Pan, SY Kao, C Li, I Kohane, J Chan, BA Yankner Nature 429 (6994), 883-891, 2004 | 2132 | 2004 |
| Gene expression in fixed tissues and outcome in hepatocellular carcinoma Y Hoshida, A Villanueva, M Kobayashi, J Peix, DY Chiang, A Camargo, ... New England Journal of Medicine 359 (19), 1995-2004, 2008 | 1329 | 2008 |
| Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma Y Hoshida, SMB Nijman, M Kobayashi, JA Chan, JP Brunet, DY Chiang, ... Cancer research 69 (18), 7385-7392, 2009 | 1179 | 2009 |
| Intertumoral heterogeneity within medulloblastoma subgroups FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ... Cancer cell 31 (6), 737-754. e6, 2017 | 1037 | 2017 |
| Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012 | 958 | 2012 |
| CDK8 is a colorectal cancer oncogene that regulates β-catenin activity R Firestein, AJ Bass, SY Kim, IF Dunn, SJ Silver, I Guney, E Freed, ... Nature 455 (7212), 547-551, 2008 | 791 | 2008 |
| The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer MM Pomerantz, N Ahmadiyeh, L Jia, P Herman, MP Verzi, ... Nature genetics 41 (8), 882-884, 2009 | 784 | 2009 |
| A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors JB Rubin, AL Kung, RS Klein, JA Chan, YP Sun, K Schmidt, MW Kieran, ... Proceedings of the National Academy of Sciences 100 (23), 13513-13518, 2003 | 734 | 2003 |
| Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ... Nature genetics 46 (5), 451-456, 2014 | 621 | 2014 |
| Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway N De La Iglesia, G Konopka, SV Puram, JA Chan, RM Bachoo, MJ You, ... Genes & development 22 (4), 449-462, 2008 | 392 | 2008 |
| Profiling critical cancer gene mutations in clinical tumor samples LE MacConaill, CD Campbell, SM Kehoe, AJ Bass, C Hatton, L Niu, ... PloS one 4 (11), e7887, 2009 | 366 | 2009 |
| Cytogenetic prognostication within medulloblastoma subgroups DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ... Journal of clinical oncology 32 (9), 886, 2014 | 356 | 2014 |
| Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis EM Thompson, T Hielscher, E Bouffet, M Remke, B Luu, S Gururangan, ... The lancet oncology 17 (4), 484-495, 2016 | 354 | 2016 |
| Childhood cerebellar tumours mirror conserved fetal transcriptional programs MC Vladoiu, I El-Hamamy, LK Donovan, H Farooq, BL Holgado, ... Nature 572 (7767), 67-73, 2019 | 353 | 2019 |
| Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort SM Waszak, PA Northcott, I Buchhalter, GW Robinson, C Sutter, ... The Lancet Oncology 19 (6), 785-798, 2018 | 348 | 2018 |
| Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers S Yip, YS Butterfield, O Morozova, S Chittaranjan, MD Blough, J An, I Birol, ... The Journal of pathology 226 (1), 7-16, 2012 | 337 | 2012 |
| Local uses of Aristolochia species and content of nephrotoxic aristolochic acid 1 and 2—A global assessment based on bibliographic sources M Heinrich, J Chan, S Wanke, C Neinhuis, MSJ Simmonds Journal of ethnopharmacology 125 (1), 108-144, 2009 | 291 | 2009 |
| Pathogenesis of Tuberous Sclerosis Subependymal Giant Cell Astrocytomas: Biallelic Inactivation of TSC1 or TSC2 Leads to mTOR Activation JA Chan, H Zhang, PS Roberts, S Jozwiak, G Wieslawa, J Lewin-Kowalik, ... Journal of Neuropathology & Experimental Neurology 63 (12), 1236-1242, 2004 | 290 | 2004 |
| BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma M Mistry, N Zhukova, D Merico, P Rakopoulos, R Krishnatry, M Shago, ... Journal of clinical oncology 33 (9), 1015, 2015 | 285 | 2015 |
