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Le T. Duong
Le T. Duong
Verified email at merck.com
Title
Cited by
Cited by
Year
Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis
T Hayami, M Pickarski, Y Zhuo, GA Wesolowski, GA Rodan, LT Duong
Bone 38 (2), 234-243, 2006
7762006
The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior …
T Hayami, M Pickarski, GA Wesolowski, J Mclane, A Bone, J Destefano, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2004
7222004
The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K
JY Gauthier, N Chauret, W Cromlish, S Desmarais, LT Duong, ...
Bioorganic & medicinal chemistry letters 18 (3), 923-928, 2008
5302008
Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells
E Jimi, I Nakamura, LT Duong, T Ikebe, N Takahashi, GA Rodan, T Suda
Experimental cell research 247 (1), 84-93, 1999
4541999
Integrins and signaling in osteoclast function
LT Duong, P Lakkakorpi, I Nakamura, GA Rodan
Matrix Biology 19 (2), 97-105, 2000
2952000
PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha (v) beta3 integrin, and phosphorylated by src kinase.
LT Duong, PT Lakkakorpi, I Nakamura, M Machwate, RM Nagy, ...
The Journal of clinical investigation 102 (5), 881-892, 1998
2951998
Role of αvβ3 integrin in osteoclast migration and formation of the sealing zone
I Nakamura, MF Pilkington, PT Lakkakorpi, L Lipfert, SM Sims, SJ Dixon, ...
Journal of cell science 112 (22), 3985-3993, 1999
2531999
Involvement of αvβ3 integrins in osteoclast function
I Nakamura, LT Duong, SB Rodan, GA Rodan
Journal of bone and mineral metabolism 25, 337-344, 2007
2502007
The osteoclast, bone remodelling and treatment of metabolic bone disease
BF Boyce, E Rosenberg, AE de Papp, LT Duong
European journal of clinical investigation 42 (12), 1332-1341, 2012
2392012
Isolation, characterization, and cDNA cloning of a vampire bat salivary plasminogen activator
SJ Gardell, LT Duong, RE Diehl, JD York, TR Hare, RB Register, ...
Journal of Biological Chemistry 264 (30), 17947-17952, 1989
2181989
Effect of the cathepsin K inhibitor odanacatib on bone resorption biomarkers in healthy postmenopausal women: two double‐blind, randomized, placebo‐controlled phase I studies
SA Stoch, S Zajic, J Stone, DL Miller, K Van Dyck, MJ Gutierrez, ...
Clinical Pharmacology & Therapeutics 86 (2), 175-182, 2009
1952009
Expression of the cartilage derived anti-angiogenic factor chondromodulin-I decreases in the early stage of experimental osteoarthritis.
T Hayami, H Funaki, K Yaoeda, K Mitui, H Yamagiwa, K Tokunaga, ...
The Journal of rheumatology 30 (10), 2207-2217, 2003
1662003
Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized …
T Cusick, CM Chen, BL Pennypacker, M Pickarski, DB Kimmel, BB Scott, ...
Journal of Bone and Mineral Research 27 (3), 524-537, 2012
1502012
Stable association of PYK2 and p130Cas in osteoclasts and their co-localization in the sealing zone
PT Lakkakorpi, I Nakamura, RM Nagy, JT Parsons, GA Rodan, LT Duong
Journal of Biological Chemistry 274 (8), 4900-4907, 1999
1381999
The αvβ3 integrin regulates α5β1-mediated cell migration toward fibronectin
KO Simon, EM Nutt, DG Abraham, GA Rodan, LT Duong
Journal of Biological Chemistry 272 (46), 29380-29389, 1997
1381997
Tyrosine phosphorylation of p130Cas is involved in actin organization in osteoclasts
I Nakamura, E Jimi, LT Duong, T Sasaki, N Takahashi, GA Rodan, T Suda
Journal of Biological Chemistry 273 (18), 11144-11149, 1998
1371998
Inhibition of cathepsin K reduces cartilage degeneration in the anterior cruciate ligament transection rabbit and murine models of osteoarthritis
T Hayami, YA Zhuo, GA Wesolowski, M Pickarski, LT Duong
Bone 50 (6), 1250-1259, 2012
1342012
PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption
PT Lakkakorpi, AJ Bett, L Lipfert, GA Rodan, T Duong
Journal of Biological Chemistry 278 (13), 11502-11512, 2003
1292003
Odanacatib reduces bone turnover and increases bone mass in the lumbar spine of skeletally mature ovariectomized rhesus monkeys
PJ Masarachia, BL Pennypacker, M Pickarski, KR Scott, GA Wesolowski, ...
Journal of Bone and Mineral Research 27 (3), 509-523, 2012
1242012
Nonpeptide αvβ3 Antagonists. Part 11:  Discovery and Preclinical Evaluation of Potent αvβ3 Antagonists for the Prevention and Treatment of Osteoporosis
PJ Coleman, KM Brashear, BC Askew, JH Hutchinson, CA McVean, ...
Journal of medicinal chemistry 47 (20), 4829-4837, 2004
1232004
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