| Van't Hoff and calorimetric enthalpies from isothermal titration calorimetry: are there significant discrepancies? JR Horn, D Russell, EA Lewis, KP Murphy Biochemistry 40 (6), 1774-1778, 2001 | 251 | 2001 |
| Allosteric inhibition through core disruption JR Horn, BK Shoichet Journal of molecular biology 336 (5), 1283-1291, 2004 | 156 | 2004 |
| A combinatorial histidine scanning library approach to engineer highly pH‐dependent protein switches ML Murtaugh, SW Fanning, TM Sharma, AM Terry, JR Horn Protein Science 20 (9), 1619-1631, 2011 | 128 | 2011 |
| A global benchmark study using affinity-based biosensors RL Rich, GA Papalia, PJ Flynn, J Furneisen, J Quinn, JS Klein, ... Analytical biochemistry 386 (2), 194-216, 2009 | 124 | 2009 |
| van't Hoff and calorimetric enthalpies II: effects of linked equilibria JR Horn, JF Brandts, KP Murphy Biochemistry 41 (23), 7501-7507, 2002 | 101 | 2002 |
| An anti‐hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop SW Fanning, JR Horn Protein Science 20 (7), 1196-1207, 2011 | 82 | 2011 |
| The Role of Protein Dynamics in Increasing Binding Affinity for an Engineered Protein− Protein Interaction Established by H/D Exchange Mass Spectrometry JR Horn, B Kraybill, EJ Petro, SJ Coales, JA Morrow, Y Hamuro, ... Biochemistry 45 (28), 8488-8498, 2006 | 61 | 2006 |
| Shotgun Alanine Scanning Shows That Growth Hormone Can Bind Productivelyto Its Receptor through a Drastically MinimizedInterface JLK Kouadio, JR Horn, G Pal, AA Kossiakoff Journal of Biological Chemistry 280 (27), 25524-25532, 2005 | 61 | 2005 |
| Structure and development of single domain antibodies as modules for therapeutics and diagnostics RJ Hoey, H Eom, JR Horn Experimental biology and medicine 244 (17), 1568-1576, 2019 | 60 | 2019 |
| Structure and energetics of protein–protein interactions: the role of conformational heterogeneity in OMTKY3 binding to serine proteases JR Horn, S Ramaswamy, KP Murphy Journal of molecular biology 331 (2), 497-508, 2003 | 59 | 2003 |
| Production and characterization of a genetically engineered anti-caffeine camelid antibody and its use in immunoaffinity chromatography EJ Franco, GJ Sonneson, TJ DeLegge, H Hofstetter, JR Horn, O Hofstetter Journal of Chromatography B 878 (2), 177-186, 2010 | 42 | 2010 |
| Hapten-induced dimerization of a single-domain VHH camelid antibody GJ Sonneson, JR Horn Biochemistry 48 (29), 6693-6695, 2009 | 32 | 2009 |
| Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins S Mukherjee, DH Griffin, JR Horn, SS Rizk, M Nocula-Lugowska, ... Journal of Biological Chemistry 293 (8), 2815-2828, 2018 | 27 | 2018 |
| Discovery of Inhibitors of Burkholderia pseudomallei Methionine Aminopeptidase with Antibacterial Activity P Wangtrakuldee, MS Byrd, CG Campos, MW Henderson, Z Zhang, ... ACS medicinal chemistry letters 4 (8), 699-703, 2013 | 27 | 2013 |
| Principal determinants leading to transition state formation of a protein–protein complex, orientation trumps side-chain interactions JR Horn, TR Sosnick, AA Kossiakoff Proceedings of the National Academy of Sciences 106 (8), 2559-2564, 2009 | 26 | 2009 |
| Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei Z Zhang, S Jakkaraju, J Blain, K Gogol, L Zhao, RC Hartley, CA Karlsson, ... Bioorganic & medicinal chemistry letters 23 (24), 6860-6863, 2013 | 17 | 2013 |
| Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents TR Helgren, C Chen, P Wangtrakuldee, TE Edwards, BL Staker, ... Bioorganic & medicinal chemistry 25 (3), 813-824, 2017 | 12 | 2017 |
| Site-directed immobilization of a genetically engineered anti-methotrexate antibody via an enzymatically introduced biotin label significantly increases the binding capacity of … KR Davenport, CA Smith, H Hofstetter, JR Horn, O Hofstetter Journal of Chromatography B 1021, 114-121, 2016 | 12 | 2016 |
| Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site SW Fanning, R Walter, JR Horn Protein Engineering, Design & Selection 27 (10), 391-397, 2014 | 12 | 2014 |
| Mutations in the coat protein-binding cis-acting RNA motifs debilitate RNA recombination of Brome mosaic virus J Sztuba-Solińska, SW Fanning, JR Horn, JJ Bujarski Virus research 170 (1-2), 138-149, 2012 | 10 | 2012 |
Timothy J. HagenNorthern Illinois UniversityVerified email at niu.edu
