Translation of Diverse Aramid- and 1,3-Dicarbonyl-peptides by Wild Type Ribosomes in Vitro O Ad, KS Hoffman, AG Cairns, AL Featherston, SJ Miller, D Söll, ... ACS central science 5 (7), 1289-1294, 2019 | 57 | 2019 |
Genetic selection for mistranslation rescues a defective co-chaperone in yeast KS Hoffman, MD Berg, BH Shilton, CJ Brandl, P O'Donoghue Nucleic acids research 45 (6), 3407-3421, 2017 | 50 | 2017 |
Visualizing tRNA-dependent mistranslation in human cells JT Lant, MD Berg, DHW Sze, KS Hoffman, IC Akinpelu, MA Turk, ... RNA biology 15 (4-5), 567-575, 2018 | 46 | 2018 |
Evolving Mistranslating tRNAs Through a Phenotypically Ambivalent Intermediate in Saccharomyces cerevisiae MD Berg, KS Hoffman, J Genereaux, S Mian, RS Trussler, DB Haniford, ... Genetics 206 (4), 1865-1879, 2017 | 28 | 2017 |
Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response KS Hoffman, ML Duennwald, J Karagiannis, J Genereaux, AS McCarton, ... G3: Genes, Genomes, Genetics 6 (6), 1649-1659, 2016 | 25 | 2016 |
Bacterial translation machinery for deliberate mistranslation of the genetic code O Vargas-Rodriguez, AH Badran, KS Hoffman, M Chen, A Crnković, ... Proceedings of the National Academy of Sciences 118 (35), e2110797118, 2021 | 18 | 2021 |
A cysteinyl-tRNA synthetase variant confers resistance against selenite toxicity and decreases selenocysteine misincorporation KS Hoffman, O Vargas-Rodriguez, DW Bak, T Mukai, LK Woodward, ... Journal of Biological Chemistry 294 (34), 12855-12865, 2019 | 18 | 2019 |
Mistranslation: from adaptations to applications KS Hoffman, P O'Donoghue, CJ Brandl Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (11), 3070-3080, 2017 | 18 | 2017 |
Covalent immune proximity-induction strategy using SuFEx-engineered bifunctional viral peptides HM McCann, BPM Lake, KS Hoffman, ME Davola, KL Mossman, AF Rullo ACS Chemical Biology 17 (5), 1269-1281, 2022 | 17 | 2022 |
Versatility of synthetic tRNAs in genetic code expansion KS Hoffman, A Crnković, D Söll Genes 9 (11), 537, 2018 | 17 | 2018 |
Mistranslation of the genetic code by a new family of bacterial transfer RNAs DB Schuntermann, JT Fischer, J Bile, SA Gaier, BA Shelley, A Awawdeh, ... Journal of Biological Chemistry 299 (7), 2023 | 11 | 2023 |
Recoding UAG to selenocysteine in Saccharomyces cerevisiae KS Hoffman, CZ Chung, T Mukai, N Krahn, HK Jiang, N Balasuriya, ... RNA 29 (9), 1400-1410, 2023 | 10 | 2023 |
Mistranslating the genetic code with leucine in yeast and mammalian cells J Davey-Young, F Hasan, R Tennakoon, P Rozik, H Moore, P Hall, ... RNA biology 21 (1), 1-23, 2024 | 6 | 2024 |
NRF2 translation block by inhibition of cap-dependent initiation sensitizes lymphoma cells to ferroptosis and CAR-T immunotherapy P Manara, AD Newsam, VVG Saralamma, MV Russo, AB Martinez, ... Biorxiv, 2024.09. 09.612133, 2024 | 2 | 2024 |
Compositions and methods for making selenocysteine containing polypeptides D Soll, T Mukai, K Hoffman US Patent 11,788,111, 2023 | 2 | 2023 |
Experimental Senecavirus A infection of bovine cell lines and colostrum-deprived calves A Buckley, L Crawford, K Hoffman, S Falkenberg Viruses 14 (12), 2809, 2022 | 2 | 2022 |
Synthetically engineered rpb1 alleles altering RNA polymerase II carboxy terminal domain phosphorylation induce discrete morphogenetic defects in Schizosaccharomyces pombe K Hoffman, H Yoo, J Karagiannis Communicative & Integrative Biology 6 (3), e23954, 2013 | 2 | 2013 |
Transfer RNA supplementation rescues HARS deficiency in a humanized yeast model of Charcot-Marie-Tooth disease SDP Wilhelm, JH Kakadia, A Beharry, R Kenana, KS Hoffman, ... Nucleic Acids Research 52 (22), 14043-14060, 2024 | 1 | 2024 |
Glutamine missense suppressor transfer RNAs inhibit polyglutamine aggregation R Tennakoon, TMI Bily, F Hasan, S Syal, A Voigt, TB Balci, KS Hoffman, ... Molecular Therapy Nucleic Acids 36 (1), 2025 | | 2025 |
Translational Disruption of NRF2 By Zotatifin Enhances Sensitivity to Ferroptosis and CAR-T Cells in Diffuse Large B-Cell Lymphoma P Manara, V Venkatarame Gowda Saralamma, AD Newsam, MV Russo, ... Blood 144 (Supplement 1), 4167-4167, 2024 | | 2024 |