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Kyle Hoffman
Kyle Hoffman
Bioinformatics Solutions Inc
Adresse e-mail validée de bioinfor.com - Page d'accueil
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Translation of Diverse Aramid- and 1,3-Dicarbonyl-peptides by Wild Type Ribosomes in Vitro
O Ad, KS Hoffman, AG Cairns, AL Featherston, SJ Miller, D Söll, ...
ACS central science 5 (7), 1289-1294, 2019
572019
Genetic selection for mistranslation rescues a defective co-chaperone in yeast
KS Hoffman, MD Berg, BH Shilton, CJ Brandl, P O'Donoghue
Nucleic acids research 45 (6), 3407-3421, 2017
502017
Visualizing tRNA-dependent mistranslation in human cells
JT Lant, MD Berg, DHW Sze, KS Hoffman, IC Akinpelu, MA Turk, ...
RNA biology 15 (4-5), 567-575, 2018
462018
Evolving Mistranslating tRNAs Through a Phenotypically Ambivalent Intermediate in Saccharomyces cerevisiae
MD Berg, KS Hoffman, J Genereaux, S Mian, RS Trussler, DB Haniford, ...
Genetics 206 (4), 1865-1879, 2017
282017
Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response
KS Hoffman, ML Duennwald, J Karagiannis, J Genereaux, AS McCarton, ...
G3: Genes, Genomes, Genetics 6 (6), 1649-1659, 2016
252016
Bacterial translation machinery for deliberate mistranslation of the genetic code
O Vargas-Rodriguez, AH Badran, KS Hoffman, M Chen, A Crnković, ...
Proceedings of the National Academy of Sciences 118 (35), e2110797118, 2021
182021
A cysteinyl-tRNA synthetase variant confers resistance against selenite toxicity and decreases selenocysteine misincorporation
KS Hoffman, O Vargas-Rodriguez, DW Bak, T Mukai, LK Woodward, ...
Journal of Biological Chemistry 294 (34), 12855-12865, 2019
182019
Mistranslation: from adaptations to applications
KS Hoffman, P O'Donoghue, CJ Brandl
Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (11), 3070-3080, 2017
182017
Covalent immune proximity-induction strategy using SuFEx-engineered bifunctional viral peptides
HM McCann, BPM Lake, KS Hoffman, ME Davola, KL Mossman, AF Rullo
ACS Chemical Biology 17 (5), 1269-1281, 2022
172022
Versatility of synthetic tRNAs in genetic code expansion
KS Hoffman, A Crnković, D Söll
Genes 9 (11), 537, 2018
172018
Mistranslation of the genetic code by a new family of bacterial transfer RNAs
DB Schuntermann, JT Fischer, J Bile, SA Gaier, BA Shelley, A Awawdeh, ...
Journal of Biological Chemistry 299 (7), 2023
112023
Recoding UAG to selenocysteine in Saccharomyces cerevisiae
KS Hoffman, CZ Chung, T Mukai, N Krahn, HK Jiang, N Balasuriya, ...
RNA 29 (9), 1400-1410, 2023
102023
Mistranslating the genetic code with leucine in yeast and mammalian cells
J Davey-Young, F Hasan, R Tennakoon, P Rozik, H Moore, P Hall, ...
RNA biology 21 (1), 1-23, 2024
62024
NRF2 translation block by inhibition of cap-dependent initiation sensitizes lymphoma cells to ferroptosis and CAR-T immunotherapy
P Manara, AD Newsam, VVG Saralamma, MV Russo, AB Martinez, ...
Biorxiv, 2024.09. 09.612133, 2024
22024
Compositions and methods for making selenocysteine containing polypeptides
D Soll, T Mukai, K Hoffman
US Patent 11,788,111, 2023
22023
Experimental Senecavirus A infection of bovine cell lines and colostrum-deprived calves
A Buckley, L Crawford, K Hoffman, S Falkenberg
Viruses 14 (12), 2809, 2022
22022
Synthetically engineered rpb1 alleles altering RNA polymerase II carboxy terminal domain phosphorylation induce discrete morphogenetic defects in Schizosaccharomyces pombe
K Hoffman, H Yoo, J Karagiannis
Communicative & Integrative Biology 6 (3), e23954, 2013
22013
Transfer RNA supplementation rescues HARS deficiency in a humanized yeast model of Charcot-Marie-Tooth disease
SDP Wilhelm, JH Kakadia, A Beharry, R Kenana, KS Hoffman, ...
Nucleic Acids Research 52 (22), 14043-14060, 2024
12024
Glutamine missense suppressor transfer RNAs inhibit polyglutamine aggregation
R Tennakoon, TMI Bily, F Hasan, S Syal, A Voigt, TB Balci, KS Hoffman, ...
Molecular Therapy Nucleic Acids 36 (1), 2025
2025
Translational Disruption of NRF2 By Zotatifin Enhances Sensitivity to Ferroptosis and CAR-T Cells in Diffuse Large B-Cell Lymphoma
P Manara, V Venkatarame Gowda Saralamma, AD Newsam, MV Russo, ...
Blood 144 (Supplement 1), 4167-4167, 2024
2024
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