Rachel Karchin
Rachel Karchin
Professor of Biomedical Engineering, Oncology and Computer Science, Johns Hopkins University
Verified email at jhu.edu - Homepage
TitleCited byYear
An integrated genomic analysis of human glioblastoma multiforme
DW Parsons, S Jones, X Zhang, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1807-1812, 2008
50252008
Integrated genomic analyses of ovarian carcinoma
Cancer Genome Atlas Research Network
Nature 474 (7353), 609, 2011
39742011
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1801-1806, 2008
35072008
The genomic landscapes of human breast and colorectal cancers
LD Wood, DW Parsons, S Jones, J Lin, T Sj÷blom, RJ Leary, D Shen, ...
Science 318 (5853), 1108-1113, 2007
31772007
The genetic landscape of the childhood cancer medulloblastoma
DW Parsons, M Li, X Zhang, S Jones, RJ Leary, JCH Lin, SM Boca, ...
science 331 (6016), 435-439, 2011
6612011
Accumulation of driver and passenger mutations during tumor progression
I Bozic, T Antal, H Ohtsuki, H Carter, D Kim, S Chen, R Karchin, ...
Proceedings of the National Academy of Sciences 107 (43), 18545-18550, 2010
6572010
MODBASE: a database of annotated comparative protein structure models and associated resources
U Pieper, N Eswar, FP Davis, H Braberg, MS Madhusudhan, A Rossi, ...
Nucleic acids research 34 (suppl_1), D291-D295, 2006
4652006
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways
J Wu, Y Jiao, M Dal Molin, A Maitra, RF De Wilde, LD Wood, JR Eshleman, ...
Proceedings of the National Academy of Sciences 108 (52), 21188-21193, 2011
4612011
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
4562018
Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene
PR Sosnay, KR Siklosi, F Van Goor, K Kaniecki, H Yu, N Sharma, ...
Nature genetics 45 (10), 1160, 2013
4172013
Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations
H Carter, S Chen, L Isik, S Tyekucheva, VE Velculescu, KW Kinzler, ...
Cancer research 69 (16), 6660-6667, 2009
4042009
Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas
Y Jiao, TM Pawlik, RA Anders, FM Selaru, MM Streppel, DJ Lucas, ...
Nature genetics 45 (12), 1470-1473, 2013
3872013
Classifying G-protein coupled receptors with support vector machines
R Karchin, K Karplus, D Haussler
Bioinformatics 18 (1), 147-159, 2002
3512002
Combining local‐structure, fold‐recognition, and new fold methods for protein structure prediction
K Karplus, R Karchin, J Draper, J Casper, Y Mandel‐Gutfreund, ...
Proteins: Structure, Function, and Bioinformatics 53 (S6), 491-496, 2003
3492003
ModBase, a database of annotated comparative protein structure models, and associated resources
U Pieper, BM Webb, DT Barkan, D Schneidman-Duhovny, A Schlessinger, ...
Nucleic acids research 39 (suppl_1), D465-D474, 2010
2852010
Evolution of neoantigen landscape during immune checkpoint blockade in non–small cell lung cancer
V Anagnostou, KN Smith, PM Forde, N Niknafs, R Bhattacharya, J White, ...
Cancer discovery 7 (3), 264-276, 2017
2802017
The genomic landscape of response to EGFR blockade in colorectal cancer
A Bertotti, E Papp, S Jones, V Adleff, V Anagnostou, B Lupo, M Sausen, ...
Nature 526 (7572), 263-267, 2015
2532015
LS-SNP: large-scale annotation of coding non-synonymous SNPs based on multiple information sources
R Karchin, M Diekhans, L Kelly, DJ Thomas, U Pieper, N Eswar, ...
Bioinformatics 21 (12), 2814-2820, 2005
2512005
A combination of molecular markers and clinical features improve the classification of pancreatic cysts
S Springer, Y Wang, M Dal Molin, DL Masica, Y Jiao, I Kinde, A Blackford, ...
Gastroenterology 149 (6), 1501-1510, 2015
2402015
Hidden Markov models that use predicted local structure for fold recognition: alphabets of backbone geometry
R Karchin, M Cline, Y Mandel‐Gutfreund, K Karplus
Proteins: Structure, Function, and Bioinformatics 51 (4), 504-514, 2003
2392003
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Articles 1–20