Water-soluble ruthenium (III)-dimethyl sulfoxide complexes: chemical behaviour and pharmaceutical properties G Mestroni, E Alessio, G Sava, S Pacor, M Coluccia, A Boccarelli Metal-Based Drugs 1 (1), 41-63, 1994 | 198 | 1994 |
Inhibition of endothelial cell functions and of angiogenesis by the metastasis inhibitor NAMI-A A Vacca, M Bruno, A Boccarelli, M Coluccia, D Ribatti, A Bergamo, ... British journal of cancer 86 (6), 993-998, 2002 | 183 | 2002 |
In vitroAntitumor Activity of 2-Acetyl Pyridine 4N-Ethyl Thiosemicarbazone and Its Platinum (II) and Palladium (II) Complexes D Kovala-Demertzi, A Boccarelli, MA Demertzis, M Coluccia Chemotherapy 53 (2), 148-152, 2007 | 98 | 2007 |
Replacement of an NH3 by an iminoether in transplatin makes an antitumor drug from an inactive compound M Leng, D Locker, MJ Giraud-Panis, A Schwartz, FP Intini, G Natile, ... Molecular Pharmacology 58 (6), 1525-1535, 2000 | 72 | 2000 |
Novel targeting of phospho-cMET overcomes drug resistance and induces antitumor activity in multiple myeloma M Moschetta, A Basile, A Ferrucci, MA Frassanito, L Rao, R Ria, ... Clinical cancer research 19 (16), 4371-4382, 2013 | 66 | 2013 |
Platinum complexes can inhibit matrix metalloproteinase activity: platinum− diethyl [(methylsulfinyl) methyl] phosphonate complexes as inhibitors of matrix metalloproteinases 2 … R Sasanelli, A Boccarelli, D Giordano, M Laforgia, F Arnesano, G Natile, ... Journal of medicinal chemistry 50 (15), 3434-3441, 2007 | 59 | 2007 |
Synthesis and in vitro antitumor activity of platinum acetonimine complexes A Boccarelli, FP Intini, R Sasanelli, MF Sivo, M Coluccia, G Natile Journal of medicinal chemistry 49 (2), 829-837, 2006 | 49 | 2006 |
Platinum (II)-acyclovir complexes: synthesis, antiviral and antitumour activity M Coluccia, A Boccarelli, C Cermelli, M Portolani, G Natile Metal-based drugs 2 (5), 249-256, 1995 | 47 | 1995 |
Platinum complexes with imino ethers or cyclic ligands mimicking imino ethers: synthesis, in vitro antitumour activity, and DNA interaction properties FP Intini, A Boccarelli, VC Francia, C Pacifico, MF Sivo, G Natile, ... JBIC Journal of Biological Inorganic Chemistry 9, 768-780, 2004 | 41 | 2004 |
Sterically hindered complexes of platinum (II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from … N Margiotta, G Natile, F Capitelli, FP Fanizzi, A Boccarelli, P De Rinaldis, ... Journal of inorganic biochemistry 100 (11), 1849-1857, 2006 | 39 | 2006 |
Cytotoxicity of some platinum (IV) complexes with ethylenediamine-N, N′-di-3-propionato ligand TJ Sabo, GN Kaluđerović, D Poleti, L Karanović, A Boccarelli, F Cannito, ... Journal of inorganic biochemistry 98 (8), 1378-1384, 2004 | 36 | 2004 |
Mechanistic insight into the inhibition of matrix metalloproteinases by platinum substrates F Arnesano, A Boccarelli, D Cornacchia, F Nushi, R Sasanelli, M Coluccia, ... Journal of medicinal chemistry 52 (23), 7847-7855, 2009 | 33 | 2009 |
Differential processing of antitumour-active and antitumour-inactive trans platinum compounds by SKOV-3 ovarian cancer cells A Boccarelli, D Giordano, G Natile, M Coluccia Biochemical pharmacology 72 (3), 280-292, 2006 | 21 | 2006 |
A New Class of 1‐Aryl‐5,6‐dihydropyrrolo[2,1‐a]isoquinoline Derivatives as Reversers of P‐Glycoprotein‐Mediated Multidrug Resistance in Tumor Cells AA Nevskaya, MD Matveeva, TN Borisova, M Niso, NA Colabufo, ... ChemMedChem 13 (15), 1588-1596, 2018 | 18 | 2018 |
Improving knowledge on the activation of bone marrow fibroblasts in MGUS and MM disease through the automatic extraction of genes via a nonnegative matrix factorization … A Boccarelli, F Esposito, M Coluccia, MA Frassanito, A Vacca, ... Journal of Translational Medicine 16 (1), 1-16, 2018 | 16 | 2018 |
Breast cancer’s microarray data: pattern discovery using nonnegative matrix factorizations N Del Buono, F Esposito, F Fumarola, A Boccarelli, M Coluccia Machine Learning, Optimization, and Big Data: Second International Workshop …, 2016 | 14 | 2016 |
An NMF-Based methodology for selecting biomarkers in the landscape of genes of heterogeneous cancer-associated fibroblast Populations F Esposito, A Boccarelli, N Del Buono Bioinformatics and Biology Insights 14, 1177932220906827, 2020 | 13 | 2020 |
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability ML Pati, P Vitale, S Ferorelli, M Iaselli, M Miciaccia, A Boccarelli, ... European Journal of Medicinal Chemistry 164, 59-76, 2019 | 12 | 2019 |
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier MG Perrone, P Vitale, S Ferorelli, A Boccarelli, M Coluccia, A Pannunzio, ... European Journal of Medicinal Chemistry 141, 404-416, 2017 | 12 | 2017 |
Novel antiproliferative biphenyl nicotinamide: NMR metabolomic study of its effect on the MCF-7 cell in comparison with cisplatin and vinblastine L Del Coco, M Majellaro, A Boccarelli, S Cellamare, CD Altomare, ... Molecules 25 (15), 3502, 2020 | 8 | 2020 |