| The structure-and metal-dependent activity of Escherichia coli PgaB provides insight into the partial de-N-acetylation of poly-β-1, 6-N-acetyl-d-glucosamine DJ Little, J Poloczek, JC Whitney, H Robinson, M Nitz, PL Howell Journal of Biological Chemistry 287 (37), 31126-31137, 2012 | 58 | 2012 |
| Identification of poly-N-acetylglucosamine as a major polysaccharide component of the Bacillus subtilis biofilm matrix D Roux, C Cywes-Bentley, YF Zhang, S Pons, M Konkol, DB Kearns, ... Journal of Biological Chemistry 290 (31), 19261-19272, 2015 | 49 | 2015 |
| Modification and periplasmic translocation of the biofilm exopolysaccharide poly-β-1, 6-N-acetyl-d-glucosamine DJ Little, G Li, C Ing, BR DiFrancesco, NC Bamford, H Robinson, M Nitz, ... Proceedings of the National Academy of Sciences 111 (30), 11013-11018, 2014 | 37 | 2014 |
| Sph3 is a glycoside hydrolase required for the biosynthesis of galactosaminogalactan in Aspergillus fumigatus NC Bamford, BD Snarr, FN Gravelat, DJ Little, MJ Lee, CA Zacharias, ... Journal of Biological Chemistry 290 (46), 27438-27450, 2015 | 33 | 2015 |
| P. aeruginosa SGNH hydrolase-like proteins AlgJ and AlgX have similar topology but separate and distinct roles in alginate acetylation P Baker, T Ricer, PJ Moynihan, EN Kitova, MTC Walvoort, DJ Little, ... PLoS pathogens 10 (8), e1004334, 2014 | 33 | 2014 |
| Functional characterization of Staphylococcus epidermidis IcaB, a de-N-acetylase important for biofilm formation V Pokrovskaya, J Poloczek, DJ Little, H Griffiths, PL Howell, M Nitz Biochemistry 52 (32), 5463-5471, 2013 | 29 | 2013 |
| Characterization of the Pseudomonas aeruginosa glycoside hydrolase PslG reveals that its levels are critical for Psl polysaccharide biosynthesis and biofilm formation P Baker, GB Whitfield, PJ Hill, DJ Little, MJ Pestrak, H Robinson, ... Journal of Biological Chemistry 290 (47), 28374-28387, 2015 | 26 | 2015 |
| Structural basis for the de-N-acetylation of poly-β-1, 6-N-acetyl-d-glucosamine in Gram-positive bacteria DJ Little, NC Bamford, V Pokrovskaya, H Robinson, M Nitz, PL Howell Journal of Biological Chemistry 289 (52), 35907-35917, 2014 | 25 | 2014 |
| The protein BpsB is a poly-β-1, 6-N-acetyl-d-glucosamine deacetylase required for biofilm formation in Bordetella bronchiseptica DJ Little, S Milek, NC Bamford, T Ganguly, BR DiFrancesco, M Nitz, ... Journal of Biological Chemistry 290 (37), 22827-22840, 2015 | 22 | 2015 |
| Combining in situ proteolysis and mass spectrometry to crystallize Escherichia coli PgaB DJ Little, JC Whitney, H Robinson, P Yip, M Nitz, PL Howell Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 20 | 2012 |
| PilN binding modulates the structure and binding partners of the Pseudomonas aeruginosa type IVa pilus protein PilM M McCallum, S Tammam, DJ Little, H Robinson, J Koo, M Shah, ... Journal of Biological Chemistry 291 (21), 11003-11015, 2016 | 19 | 2016 |
| Synthesis and evaluation of inhibitors of E. coli PgaB, a polysaccharide de-N-acetylase involved in biofilm formation A Chibba, J Poloczek, DJ Little, PL Howell, M Nitz Organic & biomolecular chemistry 10 (35), 7103-7107, 2012 | 18 | 2012 |
| In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA) D Sychantha, CS Jones, DJ Little, PJ Moynihan, H Robinson, NF Galley, ... PLoS pathogens 13 (10), e1006667, 2017 | 13 | 2017 |
| PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β (1, 6)-N-acetylglucosamine and can disrupt bacterial biofilms DJ Little, R Pfoh, F Le Mauff, NC Bamford, C Notte, P Baker, M Guragain, ... PLoS pathogens 14 (4), e1006998, 2018 | 12 | 2018 |
| PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides D Sychantha, DJ Little, RN Chapman, GJ Boons, H Robinson, PL Howell, ... Nature chemical biology 14 (1), 79, 2018 | 12 | 2018 |
| Direct Staudinger–Phosphonite Reaction Provides Methylphosphonamidates as Inhibitors of CE4 De‐N‐acetylases R Ariyakumaran, V Pokrovskaya, DJ Little, PL Howell, M Nitz ChemBioChem 16 (9), 1350-1356, 2015 | 7 | 2015 |
| Metal‐Dependent Polysaccharide Deacetylase PgaB DJ Little, NC Bamford, M Nitz, PL Howell Encyclopedia of Inorganic and Bioinorganic Chemistry, 2014 | 5 | 2014 |
| Regulatory evolution drives evasion of host inflammasomes by Salmonella Typhimurium B Ilyas, DT Mulder, DJ Little, W Elhenawy, MM Banda, D Pérez-Morales, ... Cell Reports 25 (4), 825-832. e5, 2018 | 4 | 2018 |
| Functional diversification of the NleG effector family in enterohemorrhagic Escherichia coli D Valleau, DJ Little, D Borek, T Skarina, AT Quaile, R Di Leo, S Houliston, ... Proceedings of the National Academy of Sciences 115 (40), 10004-10009, 2018 | 2 | 2018 |
| Molecular basis for CesT recognition of type III secretion effectors in enteropathogenic Escherichia coli DJ Little, BK Coombes PLoS pathogens 14 (8), e1007224, 2018 | 2 | 2018 |
Natalie C BamfordHospital for Sick ChildrenVerified email at mail.utoronto.ca
