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Justin Gainor
Justin Gainor
Director, Center for Thoracic Cancers, Massachusetts General Hospital
Verified email at partners.org
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Cited by
Year
Nivolumab versus docetaxel in advanced squamous-cell non–small-cell lung cancer
J Brahmer, KL Reckamp, P Baas, L Crinò, WEE Eberhardt, ...
New England Journal of Medicine 373 (2), 123-135, 2015
87872015
Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
NM Kuderer, TK Choueiri, DP Shah, Y Shyr, SM Rubinstein, DR Rivera, ...
The Lancet 395 (10241), 1907-1918, 2020
18172020
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma
F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ...
Cancer discovery 8 (7), 822-835, 2018
12472018
Molecular determinants of response to anti–programmed cell death (PD)-1 and anti–programmed death-ligand 1 (PD-L1) blockade in patients with non–small-cell lung cancer profiled …
H Rizvi, F Sanchez-Vega, K La, W Chatila, P Jonsson, D Halpenny, ...
Journal of clinical oncology 36 (7), 633, 2018
12242018
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis
AT Shaw, BY Yeap, BJ Solomon, GJ Riely, J Gainor, JA Engelman, ...
The lancet oncology 12 (11), 1004-1012, 2011
11352011
EGFR mutations and ALK rearrangements are associated with low response rates to PD-1 pathway blockade in non–small cell lung cancer: a retrospective analysis
JF Gainor, AT Shaw, LV Sequist, X Fu, CG Azzoli, Z Piotrowska, ...
Clinical cancer research 22 (18), 4585-4593, 2016
11082016
Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer
JF Gainor, L Dardaei, S Yoda, L Friboulet, I Leshchiner, R Katayama, ...
Cancer discovery 6 (10), 1118-1133, 2016
10952016
The ALK inhibitor ceritinib overcomes crizotinib resistance in non–small cell lung cancer
L Friboulet, N Li, R Katayama, CC Lee, JF Gainor, AS Crystal, ...
Cancer discovery 4 (6), 662-673, 2014
9012014
Patient-derived models of acquired resistance can identify effective drug combinations for cancer
AS Crystal, AT Shaw, LV Sequist, L Friboulet, MJ Niederst, EL Lockerman, ...
Science 346 (6216), 1480-1486, 2014
7812014
Efficacy of Selpercatinib in RET Fusion–Positive Non–Small-Cell Lung Cancer
A Drilon, GR Oxnard, DSW Tan, HHF Loong, M Johnson, J Gainor, ...
New England Journal of Medicine 383 (9), 813-824, 2020
6642020
Lorlatinib in non-small-cell lung cancer with ALK or ROS1 rearrangement: an international, multicentre, open-label, single-arm first-in-man phase 1 trial
AT Shaw, E Felip, TM Bauer, B Besse, A Navarro, S Postel-Vinay, ...
The Lancet Oncology 18 (12), 1590-1599, 2017
6472017
ALK Rearrangements Are Mutually Exclusive with Mutations in EGFR or KRAS: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer
JF Gainor, AM Varghese, SHI Ou, S Kabraji, MM Awad, R Katayama, ...
Clinical cancer research 19 (15), 4273-4281, 2013
6342013
First-line nivolumab plus ipilimumab in advanced non–small-cell lung cancer (CheckMate 568): outcomes by programmed death ligand 1 and tumor mutational burden as biomarkers
N Ready, MD Hellmann, MM Awad, GA Otterson, M Gutierrez, JF Gainor, ...
Journal of Clinical Oncology 37 (12), 992, 2019
5382019
Resensitization to crizotinib by the lorlatinib ALK resistance mutation L1198F
AT Shaw, L Friboulet, I Leshchiner, JF Gainor, S Bergqvist, A Brooun, ...
New England Journal of Medicine 374 (1), 54-61, 2016
5232016
Neoadjuvant atezolizumab and chemotherapy in patients with resectable non-small-cell lung cancer: an open-label, multicentre, single-arm, phase 2 trial
CA Shu, JF Gainor, MM Awad, C Chiuzan, CM Grigg, A Pabani, ...
The Lancet Oncology 21 (6), 786-795, 2020
4792020
Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice
LV Sequist, RS Heist, AT Shaw, P Fidias, R Rosovsky, JS Temel, ...
Annals of Oncology 22 (12), 2616-2624, 2011
4692011
PF-06463922, an ALK/ROS1 inhibitor, overcomes resistance to first and second generation ALK inhibitors in preclinical models
HY Zou, L Friboulet, DP Kodack, LD Engstrom, Q Li, M West, RW Tang, ...
Cancer cell 28 (1), 70-81, 2015
4622015
Nivolumab versus docetaxel in previously treated advanced non-small-cell lung cancer (CheckMate 017 and CheckMate 057): 3-year update and outcomes in patients with liver metastases
EE Vokes, N Ready, E Felip, L Horn, MA Burgio, SJ Antonia, OA Frontera, ...
Annals of oncology 29 (4), 959-965, 2018
4592018
Acquired resistance to crizotinib from a mutation in CD74–ROS1
MM Awad, R Katayama, M McTigue, W Liu, YL Deng, A Brooun, ...
New England Journal of Medicine 368 (25), 2395-2401, 2013
4522013
A combinatorial strategy for treating KRAS-mutant lung cancer
E Manchado, S Weissmueller, JP Morris, CC Chen, R Wullenkord, ...
Nature 534 (7609), 647-651, 2016
4082016
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