Floor plate-derived dopamine neurons from hESCs efficiently engraft in animal models of PD S Kriks, JW Shim, J Piao Nature 480 (7378), 547-551, 2011 | 2069* | 2011 |
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease O Cooper, H Seo, S Andrabi, C Guardia-Laguarta, J Graziotto, ... Science translational medicine 4 (141), 141ra90-141ra90, 2012 | 552 | 2012 |
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1 A Hayashi-Takagi, M Takaki, N Graziane, S Seshadri, H Murdoch, ... Nature neuroscience 13 (3), 327-332, 2010 | 487 | 2010 |
Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines Z Xie, DP Srivastava, H Photowala, L Kai, ME Cahill, KM Woolfrey, ... Neuron 56 (4), 640-656, 2007 | 408 | 2007 |
Peroxynitrite mediates neurotoxicity of amyloid β-peptide1–42-and lipopolysaccharide-activated microglia Z Xie, M Wei, TE Morgan, P Fabrizio, D Han, CE Finch, VD Longo Journal of Neuroscience 22 (9), 3484-3492, 2002 | 351 | 2002 |
Calcium entry and α-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons DI Dryanovski, JN Guzman, Z Xie, DJ Galteri, LA Volpicelli-Daley, ... Journal of Neuroscience 33 (24), 10154-10164, 2013 | 228 | 2013 |
M4 muscarinic receptor signaling ameliorates striatal plasticity deficits in models of L-DOPA-induced dyskinesia W Shen, JL Plotkin, V Francardo, WKD Ko, Z Xie, Q Li, T Fieblinger, ... Neuron 88 (4), 762-773, 2015 | 223 | 2015 |
Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington’s disease JL Plotkin, M Day, JD Peterson, Z Xie, GJ Kress, I Rafalovich, J Kondapalli, ... Neuron 83 (1), 178-188, 2014 | 218 | 2014 |
The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction TE Morgan, Z Xie, S Goldsmith, T Yoshida, AS Lanzrein, D Stone, ... Neuroscience 89 (3), 687-699, 1999 | 218 | 1999 |
Activated glia induce neuron death via MAP kinase signaling pathways involving JNK and p38 Z Xie, CJ Smith, LJ Van Eldik Glia 45 (2), 170-179, 2004 | 196 | 2004 |
Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes ME Cahill, Z Xie, M Day, H Photowala, MV Barbolina, CA Miller, C Weiss, ... Proceedings of the National Academy of Sciences 106 (31), 13058-13063, 2009 | 184 | 2009 |
Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines KM Woolfrey, DP Srivastava, H Photowala, M Yamashita, MV Barbolina, ... Nature neuroscience 12 (10), 1275-1284, 2009 | 173 | 2009 |
Aging and glial responses to lipopolysaccharide in vitro: greater induction of IL-1 and IL-6, but smaller induction of neurotoxicity Z Xie, TE Morgan, I Rozovsky, CE Finch Experimental neurology 182 (1), 135-141, 2003 | 160 | 2003 |
Activity-dependent dendritic spine structural plasticity is regulated by small GTPase Rap1 and its target AF-6 Z Xie, RL Huganir, P Penzes Neuron 48 (4), 605-618, 2005 | 123 | 2005 |
Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7 Z Xie, H Photowala, ME Cahill, DP Srivastava, KM Woolfrey, CY Shum, ... Journal of Neuroscience 28 (24), 6079-6091, 2008 | 116 | 2008 |
Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain SM Graves, Z Xie, KA Stout, E Zampese, LF Burbulla, JC Shih, ... Nature neuroscience 23 (1), 15-20, 2020 | 112 | 2020 |
Increased lysosomal exocytosis induced by lysosomal Ca2+ channel agonists protects human dopaminergic neurons from α-synuclein toxicity T Tsunemi, T Perez-Rosello, Y Ishiguro, A Yoroisaka, S Jeon, K Hamada, ... Journal of Neuroscience 39 (29), 5760-5772, 2019 | 108 | 2019 |
Cryopreservation maintains functionality of human iPSC dopamine neurons and rescues parkinsonian phenotypes in vivo DR Wakeman, BM Hiller, DJ Marmion, CW McMahon, GT Corbett, ... Stem cell reports 9 (1), 149-161, 2017 | 78 | 2017 |
Sodium channel Nax is a regulator in epithelial sodium homeostasis W Xu, SJ Hong, A Zhong, P Xie, S Jia, Z Xie, M Zeitchek, S Niknam-Bienia, ... Science translational medicine 7 (312), 312ra177-312ra177, 2015 | 65 | 2015 |
Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition ME Cahill, KA Jones, I Rafalovich, Z Xie, CS Barros, U Müller, P Penzes Molecular psychiatry 17 (1), 99-107, 2012 | 61 | 2012 |