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Lorna Farrelly
Lorna Farrelly
Postdoctoral Fellow, Department of Pharmacology & Therapeutics/Neuroscience at Mount Sinai
Verified email at mssm.edu
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Cited by
Cited by
Year
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3
LA Farrelly, RE Thompson, S Zhao, AE Lepack, Y Lyu, NV Bhanu, ...
Nature 567 (7749), 535-539, 2019
3582019
Critical role of histone turnover in neuronal transcription and plasticity
I Maze, W Wenderski, KM Noh, RC Bagot, N Tzavaras, I Purushothaman, ...
Neuron 87 (1), 77-94, 2015
3052015
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking
AE Lepack, CT Werner, AF Stewart, SL Fulton, P Zhong, LA Farrelly, ...
Science 368 (6487), 197-201, 2020
1772020
Aberrant H3. 3 dynamics in NAc promote vulnerability to depressive-like behavior
AE Lepack, RC Bagot, CJ Peña, YHE Loh, LA Farrelly, Y Lu, SK Powell, ...
Proceedings of the National Academy of Sciences 113 (44), 12562-12567, 2016
592016
Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence
L Farrelly, M Föcking, Y Piontkewitz, P Dicker, J English, K Wynne, ...
Developmental neuroscience 37 (1), 43-55, 2015
462015
Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout
S Zhao, KN Chuh, B Zhang, BE Dul, RE Thompson, LA Farrelly, X Liu, ...
Proceedings of the National Academy of Sciences 118 (6), e2016742118, 2021
422021
An emerging perspective on ‘histone code’mediated regulation of neural plasticity and disease
LA Farrelly, I Maze
Current opinion in neurobiology 59, 157-163, 2019
202019
Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia
LA Farrelly, S Zheng, N Schrode, A Topol, NV Bhanu, RM Bastle, ...
Nature communications 13 (1), 2195, 2022
182022
Adolescent Risperidone treatment alters protein expression associated with protein trafficking and cellular metabolism in the adult rat prefrontal cortex
LA Farrelly, P Dicker, K Wynne, J English, G Cagney, M Föcking, ...
Proteomics 14 (12), 1574-1578, 2014
172014
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome
SL Fulton, W Wenderski, AE Lepack, AL Eagle, T Fanutza, RM Bastle, ...
Nature Communications 13 (1), 6384, 2022
82022
Current proteomic methods to investigate the dynamics of histone turnover in the central nervous system
LA Farrelly, BD Dill, H Molina, MR Birtwistle, I Maze
Methods in enzymology 574, 331-354, 2016
52016
The effects of prenatal iron deficiency and risperidone treatment on the rat frontal cortex: a proteomic analysis
L Farrelly, MV Rosato‐Siri, M Föcking, M Codagnone, A Reines, P Dicker, ...
Proteomics 17 (17-18), 1600407, 2017
42017
Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-induced gene expression and behavior.
A Al-Kachak, SL Fulton, LA Farrelly, AE Lepack, RM Bastle, L Kong, ...
Biorxiv: the Preprint Server for Biology, 2023
22023
Early-life stress alters chromatin modifications in VTA to prime stress sensitivity
LT Geiger, JAR Balouek, LA Farrelly, AS Chen, M Tang, SN Bennett, ...
bioRxiv, 2024.03. 14.584631, 2024
12024
Insights from Proteomic Studies on Schizophrenia Preclinical Models: What Can We Learn for Drug Discovery?
LA Farrelly, M Föcking, DR Cotter
Proteomics and Metabolomics in Psychiatry 29, 56-73, 2014
12014
Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-and antidepressant-mediated gene expression and behavior
A Al-Kachak, SL Fulton, G Di Salvo, JC Chan, LA Farrelly, AE Lepack, ...
bioRxiv, 2023
2023
A Female‐specific Role of RGS20 in Transcriptional, Epigenomic and Behavioral Responses to Chronic Pain
A Ruiz, S Gaspari, L Farrelly, C Polizu, K Pryce, A Ramakrishnan, ...
The FASEB Journal 35, 2021
2021
T9. EPIGENETIC PROFILING IN SCHIZOPHRENIA DERIVED HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) AND NEURONS
L Farrelly, S Zhang, E Flaherty, A Topol, N Schrode, R Bastle, N Bhanu, ...
Schizophrenia Bulletin 46 (Suppl 1), S234, 2020
2020
Deciphering Roles for Aberrant Histone Dopaminylation in Drug Addiction
I Maze, A Lepack, L Farrelly, C Werner, A Smith, Y Lyu, R Thompson, ...
NEUROPSYCHOPHARMACOLOGY 43, S504-S505, 2018
2018
Transcriptional Priming by Enduring Chromatin Modifications After Early Life Stress
C Pena, YHE Loh, L Farrelly, S Espeso-Gil, B Garcia, S Akbarian, L Shen, ...
NEUROPSYCHOPHARMACOLOGY 43, S401-S401, 2018
2018
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