John Robert Tyson
John Robert Tyson
Senior Scientist Microbial Genomics BCCDC
Verified email at
Cited by
Cited by
Nanopore sequencing and assembly of a human genome with ultra-long reads
M Jain, S Koren, KH Miga, J Quick, AC Rand, TA Sasani, JR Tyson, ...
Nature biotechnology 36 (4), 338-345, 2018
Nanopore native RNA sequencing of a human poly (A) transcriptome
RE Workman, AD Tang, PS Tang, M Jain, JR Tyson, R Razaghi, ...
Nature methods 16 (12), 1297-1305, 2019
Gene expression profiling of cells, tissues, and developmental stages of the nematode C. elegans
SJ McKay, R Johnsen, J Khattra, J Asano, DL Baillie, S Chan, N Dube, ...
Cold Spring Harbor symposia on quantitative biology 68, 159-170, 2003
Improvements to the ARTIC multiplex PCR method for SARS-CoV-2 genome sequencing using nanopore
JR Tyson, P James, D Stoddart, N Sparks, A Wickenhagen, G Hall, ...
BioRxiv, 2020
MinION Analysis and Reference Consortium: Phase 1 data release and analysis
CLC Ip, M Loose, JR Tyson, M de Cesare, BL Brown, M Jain, RM Leggett, ...
F1000Research 4, 2015
Coordinated activation of Hsp70 chaperones
GJ Steel, DM Fullerton, JR Tyson, CJ Stirling
Science 303 (5654), 98-101, 2004
The cellular mechanisms of neuronal swelling underlying cytotoxic edema
RL Rungta, HB Choi, JR Tyson, A Malik, L Dissing-Olesen, PJC Lin, ...
Cell 161 (3), 610-621, 2015
LHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulum
JR Tyson, CJ Stirling
The EMBO journal, 2000
A Cav3. 2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy
KL Powell, SM Cain, C Ng, S Sirdesai, LS David, M Kyi, E Garcia, ...
Journal of Neuroscience 29 (2), 371-380, 2009
MinION-based long-read sequencing and assembly extends the Caenorhabditis elegans reference genome
JR Tyson, NJ O'Neil, M Jain, HE Olsen, P Hieter, TP Snutch
Genome research 28 (2), 266-274, 2018
MinION Analysis and Reference Consortium: Phase 2 data release and analysis of R9. 0 chemistry
M Jain, JR Tyson, M Loose, CLC Ip, DA Eccles, J O'Grady, S Malla, ...
F1000Research 6, 2017
Two-dose SARS-CoV-2 vaccine effectiveness with mixed schedules and extended dosing intervals: test-negative design studies from British Columbia and Quebec, Canada
DM Skowronski, S Setayeshgar, Y Febriani, M Ouakki, M Zou, D Talbot, ...
MedRxiv, 2021.10. 26.21265397, 2021
A novel subfamily of Hsp70s in the endoplasmic reticulum
A Rachel, JR Tyson, CJ Stirling
Trends in Cell Biology 7 (7), 277-282, 1997
Ssh1p determines the translocation and dislocation capacities of the yeast endoplasmic reticulum
BM Wilkinson, JR Tyson, CJ Stirling
Developmental cell 1 (3), 401-409, 2001
Distinct domains within yeast Sec61p involved in post-translational translocation and protein dislocation
BM Wilkinson, JR Tyson, PJ Reid, CJ Stirling
Journal of Biological Chemistry 275 (1), 521-529, 2000
Splice-variant changes of the CaV3.2 T-type calcium channel mediate voltage-dependent facilitation and associate with cardiac hypertrophy and development
LS David, E Garcia, SM Cain, E Thau, JR Tyson, TP Snutch
Channels 4 (5), 375-389, 2010
Molecular nature of voltage‐gated calcium channels: structure and species comparison
JR Tyson, TP Snutch
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling 2 (5), 181-206, 2013
In vivo imaging reveals that pregabalin inhibits cortical spreading depression and propagation to subcortical brain structures
SM Cain, B Bohnet, J LeDue, AC Yung, E Garcia, JR Tyson, SRA Alles, ...
Proceedings of the National Academy of Sciences 114 (9), 2401-2406, 2017
COVID-19 in an immunocompromised host: persistent shedding of viable SARS-CoV-2 and emergence of multiple mutations: a case report
WF Leung, S Chorlton, J Tyson, GN Al-Rawahi, AN Jassem, N Prystajecky, ...
International Journal of Infectious Diseases 114, 178-182, 2022
CaV3.2 drives sustained burst‐firing, which is critical for absence seizure propagation in reticular thalamic neurons
SM Cain, JR Tyson, HB Choi, R Ko, PJC Lin, JM LeDue, KL Powell, ...
Epilepsia 59 (4), 778-791, 2018
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