Leonard Goldstein
Leonard Goldstein
Scientist (Bioinformatics) at Genentech
Verified email at gene.com
TitleCited byYear
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
C Blenkiron, LD Goldstein, NP Thorne, I Spiteri, SF Chin, MJ Dunning, ...
Genome biology 8 (10), R214, 2007
piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans
A Ashe, A Sapetschnig, EM Weick, J Mitchell, MP Bagijn, AC Cording, ...
Cell 150 (1), 88-99, 2012
Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline
PP Das, MP Bagijn, LD Goldstein, JR Woolford, NJ Lehrbach, ...
Molecular cell 31 (1), 79-90, 2008
Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
R Bueno, EW Stawiski, LD Goldstein, S Durinck, A De Rienzo, ...
Nature genetics 48 (4), 407, 2016
Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses
MA Félix, A Ashe, J Piffaretti, G Wu, I Nuez, T Bélicard, Y Jiang, G Zhao, ...
PLoS biology 9 (1), e1000586, 2011
Function, targets, and evolution of Caenorhabditis elegans piRNAs
MP Bagijn, LD Goldstein, A Sapetschnig, EM Weick, S Bouasker, ...
Science 337 (6094), 574-578, 2012
Global microRNA profiles in cervical squamous cell carcinoma depend on Drosha expression levels
B Muralidhar, LD Goldstein, G Ng, DM Winder, RD Palmer, EL Gooding, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2007
Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses
K Srinivasan, BA Friedman, JL Larson, BE Lauffer, LD Goldstein, ...
Nature communications 7, 11295, 2016
Characterisation of microRNA expression in post-natal mouse mammary gland development
S Avril-Sassen, LD Goldstein, J Stingl, C Blenkiron, J Le Quesne, I Spiteri, ...
BMC genomics 10 (1), 548, 2009
miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones
ML Baudet, KH Zivraj, C Abreu-Goodger, A Muldal, J Armisen, ...
Nature neuroscience 15 (1), 29, 2012
The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans
AM Clark, LD Goldstein, M Tevlin, S Tavare, S Shaham, EA Miska
Nucleic acids research 38 (11), 3780-3793, 2010
Reduced Insulin/IGF-1 Signaling Restores Germ Cell Immortality to Caenorhabditis elegans Piwi Mutants
M Simon, P Sarkies, K Ikegami, AL Doebley, LD Goldstein, J Mitchell, ...
Cell reports 7 (3), 762-773, 2014
Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers
LD Goldstein, J Lee, F Gnad, C Klijn, A Schaub, J Reeder, A Daemen, ...
Cell reports 16 (10), 2605-2617, 2016
Complex regulation of ADAR-mediated RNA-editing across tissues
MA Huntley, M Lou, LD Goldstein, M Lawrence, GJP Dijkgraaf, ...
BMC genomics 17 (1), 61, 2016
Massively parallel nanowell-based single-cell gene expression profiling
LD Goldstein, YJJ Chen, J Dunne, A Mir, H Hubschle, J Guillory, W Yuan, ...
BMC genomics 18 (1), 519, 2017
Prediction and quantification of splice events from RNA-seq data
LD Goldstein, Y Cao, G Pau, M Lawrence, TD Wu, S Seshagiri, ...
PloS one 11 (5), e0156132, 2016
A peptide filtering relation quantifies MHC class I peptide optimization
N Dalchau, A Phillips, LD Goldstein, M Howarth, L Cardelli, S Emmott, ...
PLoS computational biology 7 (10), e1002144, 2011
Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populations
A Sakaguchi, P Sarkies, M Simon, AL Doebley, LD Goldstein, A Hedges, ...
Proceedings of the National Academy of Sciences 111 (41), E4323-E4331, 2014
Comprehensive genomic analysis identifies pathogenic variants in maturity-onset diabetes of the young (MODY) patients in South India
V Mohan, V Radha, TT Nguyen, EW Stawiski, KB Pahuja, LD Goldstein, ...
BMC medical genetics 19 (1), 22, 2018
An empirical approach leveraging tumorgrafts to dissect the tumor microenvironment in renal cell carcinoma identifies missing link to prognostic inflammatory factors
T Wang, R Lu, P Kapur, BS Jaiswal, R Hannan, Z Zhang, I Pedrosa, ...
Cancer discovery 8 (9), 1142-1155, 2018
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