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William P Clarke
William P Clarke
Professor of Pharmacology, University of Texas Health Science Center
Verified email at uthscsa.edu
Title
Cited by
Cited by
Year
Functional selectivity and classical concepts of quantitative pharmacology
JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007
13062007
Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus
KA Berg, S Maayani, J Goldfarb, C Scaramellini, P Leff, WP Clarke
Molecular pharmacology 54 (1), 94-104, 1998
6051998
Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens
P De Deurwaerdère, S Navailles, KA Berg, WP Clarke, U Spampinato
Journal of Neuroscience 24 (13), 3235-3241, 2004
3812004
RNA‐editing of the 5‐HT2C receptor alters agonist‐receptor‐effector coupling specificity
KA Berg, JD Cropper, CM Niswender, E Sanders‐Bush, RB Emeson, ...
British journal of pharmacology 134 (2), 386-392, 2001
1752001
Bradykinin-induced functional competence and trafficking of the δ-opioid receptor in trigeminal nociceptors
AM Patwardhan, KA Berg, AN Akopain, NA Jeske, N Gamper, WP Clarke, ...
Journal of Neuroscience 25 (39), 8825-8832, 2005
1742005
Signal transduction differences between 5-hydroxytryptamine type 2A and type 2C receptor systems.
KA Berg, WP Clarke, C Sailstad, A Saltzman, S Maayani
Molecular pharmacology 46 (3), 477-484, 1994
1641994
Physiological relevance of constitutive activity of 5-HT2A and 5-HT2C receptors
KA Berg, JA Harvey, U Spampinato, WP Clarke
Trends in pharmacological sciences 26 (12), 625-630, 2005
1482005
Making sense of pharmacology: inverse agonism and functional selectivity
KA Berg, WP Clarke
International Journal of Neuropsychopharmacology 21 (10), 962-977, 2018
1442018
Lack of 5-hydroxytryptamine1A-mediated inhibition of adenylyl cyclase in dorsal raphe of male and female rats.
WP Clarke, FD Yocca, S Maayani
Journal of Pharmacology and Experimental Therapeutics 277 (3), 1259-1266, 1996
1331996
The elusive nature of intrinsic efficacy
WP Clarke, RA Bond
Trends in pharmacological sciences 19 (7), 270-276, 1998
1321998
Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors
VJ Aloyo, KA Berg, U Spampinato, WP Clarke, JA Harvey
Pharmacology & therapeutics 121 (2), 160-173, 2009
1312009
Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT) 2A and 5-HT2C receptors
PR Moya, KA Berg, MA Gutierrez-Hernandez, P Saez-Briones, ...
Journal of Pharmacology and Experimental Therapeutics 321 (3), 1054-1061, 2007
1262007
Novel actions of inverse agonists on 5-HT2C receptor systems
KA Berg, BD Stout, JD Cropper, S Maayani, WP Clarke
Molecular pharmacology 55 (5), 863-872, 1999
1181999
Fine-tuning serotonin2c receptor function in the brain: molecular and functional implications
KA Berg, WP Clarke, KA Cunningham, U Spampinato
Neuropharmacology 55 (6), 969-976, 2008
1132008
Intracellular Ca2+ regulates amphetamine-induced dopamine efflux and currents mediated by the human dopamine transporter
ME Gnegy, H Khoshbouei, KA Berg, JA Javitch, WP Clarke, M Zhang, ...
Molecular pharmacology 66 (1), 137-143, 2004
1102004
Conflicting responses: the experiences of fathers of infants diagnosed with severe congenital heart disease
SM Clark, MS Miles
Journal for Specialists in Pediatric Nursing 4 (1), 7-14, 1999
1101999
Physiological and therapeutic relevance of constitutive activity of 5-HT2A and 5-HT2C receptors for the treatment of depression
KA Berg, JA Harvey, U Spampinato, WP Clarke
Progress in brain research 172, 287-305, 2008
1032008
Pleiotropic Behavior of 5‐HT2A and 5‐HT2C Receptor Agonists
KA Berg, WP Clarke, S Maayani, J Goldfarb
Annals of the New York Academy of Sciences 861 (1), 104-110, 1998
971998
5-Hydroxytryptamine type 2A receptors regulate cyclic AMP accumulation in a neuronal cell line by protein kinase C-dependent and calcium/calmodulin-dependent mechanisms.
KA Berg, WP Clarke, Y Chen, BJ Ebersole, RD McKay, S Maayani
Molecular Pharmacology 45 (5), 826-836, 1994
891994
Differences in rapid desensitization of 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptor-mediated phospholipase C activation
KA Berg, BD Stout, S Maayani, WP Clarke
Journal of Pharmacology and Experimental Therapeutics 299 (2), 593-602, 2001
882001
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