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Olivier Julien
Olivier Julien
Associate Professor, University of Alberta
Verified email at ualberta.ca - Homepage
Title
Cited by
Cited by
Year
Caspases and their substrates
O Julien, JA Wells
Cell Death & Differentiation 24 (8), 1380-1389, 2017
7462017
The DegraBase: A Database of Proteolysis in Healthy and Apoptotic Human Cells
ED Crawford, JE Seaman, N Agard, GW Hsu, O Julien, S Mahrus, ...
Molecular & Cellular Proteomics 12 (3), 813-824, 2013
1522013
Mapping interactions with the chaperone network reveals factors that protect against tau aggregation
SA Mok, C Condello, R Freilich, A Gillies, T Arhar, J Oroz, H Kadavath, ...
Nature structural & molecular biology 25 (5), 384-393, 2018
1302018
Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles
O Julien, M Zhuang, AP Wiita, AJ O’Donoghue, GM Knudsen, CS Craik, ...
Proceedings of the National Academy of Sciences 113 (14), E2001-E2010, 2016
1102016
Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau
R Freilich, M Betegon, E Tse, SA Mok, O Julien, DA Agard, ...
Nature Communications 9 (1), 4563, 2018
892018
Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins
AJ Martinko, C Truillet, O Julien, JE Diaz, MA Horlbeck, G Whiteley, ...
eLife 7, e31098, 2018
842018
Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues
JE Seaman, O Julien, PS Lee, TJ Rettenmaier, ND Thomsen, JA Wells
Cell Death & Differentiation 23 (10), 1717-1726, 2016
822016
Comparative analysis of mitochondrial N-termini from mouse, human, and yeast
SE Calvo, O Julien, KR Clauser, H Shen, KJ Kamer, JA Wells, VK Mootha
Molecular & Cellular Proteomics 16 (4), 512-523, 2017
802017
Global cellular response to chemotherapy-induced apoptosis
AP Wiita, E Ziv, PJ Wiita, A Urisman, O Julien, AL Burlingame, ...
Elife 2, e01236, 2013
762013
Deorphanizing caspase-3 and caspase-9 substrates in and out of apoptosis with deep substrate profiling
LE Araya, IV Soni, JA Hardy, O Julien
ACS Chemical Biology 16 (11), 2280-2296, 2021
672021
The Unique Cofactor Region of Zika Virus NS2B–NS3 Protease Facilitates Cleavage of Key Host Proteins
ME Hill, A Kumar, JA Wells, TC Hobman, O Julien, JA Hardy
ACS chemical biology 13 (9), 2398-2405, 2018
602018
Unraveling the mechanism of cell death induced by chemical fibrils
O Julien, M Kampmann, MC Bassik, JA Zorn, VJ Venditto, K Shimbo, ...
Nature chemical biology 10 (11), 969-976, 2014
552014
Structure–activity relationship and molecular mechanics reveal the importance of ring entropy in the biosynthesis and activity of a natural product
HL Tran, KW Lexa, O Julien, TS Young, CT Walsh, MP Jacobson, ...
Journal of the American Chemical Society 139 (7), 2541-2544, 2017
492017
Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies
SB Pollock, A Hu, Y Mou, AJ Martinko, O Julien, M Hornsby, L Ploder, ...
Proceedings of the National Academy of Sciences 115 (11), 2836-2841, 2018
482018
Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades
SR Srinivasan, LC Cesa, X Li, O Julien, M Zhuang, H Shao, J Chung, ...
Molecular Cancer Research 16 (1), 58-68, 2018
482018
Reprogramming Caspase-7 specificity by regio-specific mutations and selection provides alternate solutions for substrate recognition
ME Hill, DJ MacPherson, P Wu, O Julien, JA Wells, JA Hardy
ACS chemical biology 11 (6), 1603-1612, 2016
432016
Differential stability of the bovine prion protein upon urea unfolding
O Julien, S Chatterjee, A Thiessen, SP Graether, BD Sykes
Protein Science 18 (10), 2172-2182, 2009
412009
Turning on caspases with genetics and small molecules
CW Morgan, O Julien, EK Unger, NM Shah, JA Wells
Methods in enzymology 544, 179-213, 2014
382014
Is there nascent structure in the intrinsically disordered region of troponin I?
O Julien, P Mercier, CN Allen, O Fisette, CHI Ramos, P Lagüe, ...
Proteins: Structure, Function, and Bioinformatics 79 (4), 1240-1250, 2011
332011
Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir
O Julien, JR Beadle, WC Magee, S Chatterjee, KY Hostetler, DH Evans, ...
Journal of the American Chemical Society 133 (7), 2264-2274, 2011
332011
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