| SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields J Frank, M Radermacher, P Penczek, J Zhu, Y Li, M Ladjadj, A Leith Journal of structural biology 116 (1), 190-199, 1996 | 2348 | 1996 |
| Three-dimensional electron microscopy of macromolecular assemblies: visualization of biological molecules in their native state J Frank Oxford university press, 2006 | 1839 | 2006 |
| Electron tomography J Frank Plenum, 1992 | 1322* | 1992 |
| A ratchet-like inter-subunit reorganization of the ribosome during translocation J Frank, RK Agrawal Nature 406 (6793), 318-322, 2000 | 1012 | 2000 |
| Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics LG Trabuco, E Villa, K Mitra, J Frank, K Schulten Structure 16 (5), 673-683, 2008 | 972 | 2008 |
| Use of multivariates statistics in analysing the images of biological macromolecules M Van Heel, J Frank Ultramicroscopy 6 (1), 187-194, 1981 | 770 | 1981 |
| Locking and unlocking of ribosomal motions M Valle, A Zavialov, J Sengupta, U Rawat, M Ehrenberg, J Frank Cell 114 (1), 123-134, 2003 | 722 | 2003 |
| Hepatitis C Virus IRES RNA-Induced Changes in the Conformation of the 40S Ribosomal Subunit CMT Spahn, JS Kieft, RA Grassucci, PA Penczek, K Zhou, JA Doudna, ... Science 291 (5510), 1959-1962, 2001 | 659 | 2001 |
| Structure of the 80S ribosome from Saccharomyces cerevisiae—tRNA-ribosome and subunit-subunit interactions CMT Spahn, R Beckmann, N Eswar, PA Penczek, A Sali, G Blobel, ... Cell 107 (3), 373-386, 2001 | 652 | 2001 |
| Molecular architecture of the human pre-mRNA 3′ processing complex Y Shi, DC Di Giammartino, D Taylor, A Sarkeshik, WJ Rice, JR Yates, ... Molecular cell 33 (3), 365-376, 2009 | 618 | 2009 |
| Three‐dimensional reconstruction from a single‐exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli M Radermacher, T Wagenknecht, A Verschoor, J Frank Journal of microscopy 146 (2), 113-136, 1987 | 602 | 1987 |
| Focused-ion-beam thinning of frozen-hydrated biological specimens for cryo-electron microscopy M Marko, C Hsieh, R Schalek, J Frank, C Mannella Nature methods 4 (3), 215-217, 2007 | 556 | 2007 |
| Three-dimensional reconstruction of single particles embedded in ice P Penczek, M Radermacher, J Frank Ultramicroscopy 40 (1), 33-53, 1992 | 553 | 1992 |
| SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs TR Shaikh, H Gao, WT Baxter, FJ Asturias, N Boisset, A Leith, J Frank Nature protocols 3 (12), 1941-1974, 2008 | 540 | 2008 |
| A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome J Frank, J Zhu, P Penczek, Y Li, S Srivastava, A Verschoor, ... Nature 376 (6539), 441-444, 1995 | 531 | 1995 |
| Solution structure of the E. coli 70S ribosome at 11.5 Å resolution IS Gabashvili, RK Agrawal, CMT Spahn, RA Grassucci, DI Svergun, ... Cell 100 (5), 537-549, 2000 | 516 | 2000 |
| Structure of the signal recognition particle interacting with the elongation-arrested ribosome M Halic, T Becker, MR Pool, CMT Spahn, RA Grassucci, J Frank, ... Nature 427 (6977), 808-814, 2004 | 514 | 2004 |
| The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles PA Penczek, RA Grassucci, J Frank Ultramicroscopy 53 (3), 251-270, 1994 | 505 | 1994 |
| Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation CMT Spahn, MG Gomez‐Lorenzo, RA Grassucci, R Jørgensen, ... The EMBO journal 23 (5), 1008-1019, 2004 | 503 | 2004 |
| Outcome of the first electron microscopy validation task force meeting R Henderson, A Sali, ML Baker, B Carragher, B Devkota, KH Downing, ... Structure 20 (2), 205-214, 2012 | 501 | 2012 |
Robert A GrassucciResearch Specialist Columbia/HHMIVerified email at columbia.edu
