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Juan Luis Concepción
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Year
Amiodarone Has Intrinsic Anti-Trypanosoma cruzi Activity and Acts Synergistically with Posaconazole
G Benaim, JM Sanders, Y Garcia-Marchán, C Colina, R Lira, AR Caldera, ...
Journal of medicinal chemistry 49 (3), 892-899, 2006
2452006
Squalene synthase as a chemotherapeutic target in Trypanosoma cruzi and Leishmania mexicana
JA Urbina, JL Concepcion, S Rangel, G Visbal, R Lira
Molecular and Biochemical Parasitology 125 (1-2), 35-45, 2002
1602002
In Vitro and In Vivo Activities of E5700 and ER-119884, Two Novel Orally Active Squalene Synthase Inhibitors, against Trypanosoma cruzi
JA Urbina, JL Concepcion, A Caldera, G Payares, C Sanoja, T Otomo, ...
Antimicrobial agents and chemotherapy 48 (7), 2379-2387, 2004
1302004
Enolase: a key player in the metabolism and a probable virulence factor of trypanosomatid parasites—perspectives for its use as a therapeutic target
L Avilán, M Gualdrón-López, W Quiñones, L González-González, ...
Enzyme research 2011, 2011
1292011
When, how and why glycolysis became compartmentalised in the Kinetoplastea. A new look at an ancient organelle
M Gualdrón-López, A Brennand, V Hannaert, W Quiñones, AJ Cáceres, ...
International journal for parasitology 42 (1), 1-20, 2012
1252012
Enolase as a plasminogen binding protein in Leishmania mexicana
G Vanegas, W Quiñones, C Carrasco-López, JL Concepción, F Albericio, ...
Parasitology research 101, 1511-1516, 2007
1252007
Inhibition of Trypanosoma cruzi Hexokinase by Bisphosphonates
MP Hudock, CE Sanz-Rodriguez, Y Song, JMW Chan, Y Zhang, S Odeh, ...
Journal of medicinal chemistry 49 (1), 215-223, 2006
992006
Inhibition of Trypanosoma cruzi growth in vitro by Solanum alkaloids: a comparison with ketoconazole
B Chataing, JL Concepción, R Lobaton, A Usubillaga
Planta medica 64 (01), 31-36, 1998
991998
Molecular and biochemical characterization of hexokinase from Trypanosoma cruzi
AJ Cáceres, R Portillo, H Acosta, D Rosales, W Quiñones, L Avilan, ...
Molecular and biochemical parasitology 126 (2), 251-262, 2003
952003
Extracellular functions of glycolytic enzymes of parasites: unpredicted use of ancient proteins
A Gómez-Arreaza, H Acosta, W Quiñones, JL Concepción, PAM Michels, ...
Molecular and biochemical parasitology 193 (2), 75-81, 2014
942014
In Vitro Activities of ER-119884 and E5700, Two Potent Squalene Synthase Inhibitors, against Leishmania amazonensis: Antiproliferative, Biochemical, and …
JC Fernandes Rodrigues, JL Concepcion, C Rodrigues, A Caldera, ...
Antimicrobial agents and chemotherapy 52 (11), 4098-4114, 2008
932008
Bisphosphonates as inhibitors of Trypanosoma cruzi hexokinase: kinetic and metabolic studies
CE Sanz-Rodríguez, JL Concepcion, S Pekerar, E Oldfield, JA Urbina
Journal of Biological Chemistry 282 (17), 12377-12387, 2007
892007
Pyruvate phosphate dikinase and pyrophosphate metabolism in the glycosome of Trypanosoma cruzi epimastigotes
H Acosta, M Dubourdieu, W Quiñones, A Cáceres, F Bringaud, ...
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2004
762004
3-Hydroxy-3-methyl-glutaryl-CoA Reductase inTrypanosoma (Schizotrypanum) cruzi: Subcellular Localization and Kinetic Properties
JL Concepcion, D Gonzalez-Pacanowska, JA Urbina
Archives of biochemistry and biophysics 352 (1), 114-120, 1998
701998
Mechanism of Action of 4-Phenoxyphenoxyethyl Thiocyanate (WC-9) against Trypanosoma cruzi, the Causative Agent of Chagas’ Disease
JA Urbina, JL Concepcion, A Montalvetti, JB Rodriguez, R Docampo
Antimicrobial agents and chemotherapy 47 (6), 2047-2050, 2003
662003
Estudio seroepidemiológico y entomológico sobre la enfermedad de Chagas en un área infestada por Triatoma maculata (Erichson 1848) en el centro-occidente de Venezuela
ME Rojas, P Várquez, MF Villarreal, C Velandia, L Vergara, ...
Cadernos de Saúde Pública 24 (10), 2323-2333, 2008
642008
Leishmania mexicana: molecular cloning and characterization of enolase
W Quiñones, P Peña, M Domingo-Sananes, A Cáceres, PAM Michels, ...
Experimental parasitology 116 (3), 241-251, 2007
612007
Molecular and biochemical characterization of novel glucokinases from Trypanosoma cruzi and Leishmania spp.
AJ Cáceres, W Quiñones, M Gualdrón, A Cordeiro, L Avilán, PAM Michels, ...
Molecular and biochemical parasitology 156 (2), 235-245, 2007
582007
The glycosome membrane of Trypanosoma cruzi epimastigotes: protein and lipid composition
W Quiñones, JA Urbina, M Dubourdieu, JL Concepción
Experimental parasitology 106 (3-4), 135-149, 2004
552004
Glycosomal targets for anti-trypanosomatid drug discovery
X Barros-Alvarez, M Gualdron-Lopez, H Acosta, AJ Caceres, ...
Current medicinal chemistry 21 (15), 1679-1706, 2014
522014
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