Amiodarone Has Intrinsic Anti-Trypanosoma cruzi Activity and Acts Synergistically with Posaconazole G Benaim, JM Sanders, Y Garcia-Marchán, C Colina, R Lira, AR Caldera, ... Journal of medicinal chemistry 49 (3), 892-899, 2006 | 245 | 2006 |
Squalene synthase as a chemotherapeutic target in Trypanosoma cruzi and Leishmania mexicana JA Urbina, JL Concepcion, S Rangel, G Visbal, R Lira Molecular and Biochemical Parasitology 125 (1-2), 35-45, 2002 | 160 | 2002 |
In Vitro and In Vivo Activities of E5700 and ER-119884, Two Novel Orally Active Squalene Synthase Inhibitors, against Trypanosoma cruzi JA Urbina, JL Concepcion, A Caldera, G Payares, C Sanoja, T Otomo, ... Antimicrobial agents and chemotherapy 48 (7), 2379-2387, 2004 | 130 | 2004 |
Enolase: a key player in the metabolism and a probable virulence factor of trypanosomatid parasites—perspectives for its use as a therapeutic target L Avilán, M Gualdrón-López, W Quiñones, L González-González, ... Enzyme research 2011, 2011 | 129 | 2011 |
When, how and why glycolysis became compartmentalised in the Kinetoplastea. A new look at an ancient organelle M Gualdrón-López, A Brennand, V Hannaert, W Quiñones, AJ Cáceres, ... International journal for parasitology 42 (1), 1-20, 2012 | 125 | 2012 |
Enolase as a plasminogen binding protein in Leishmania mexicana G Vanegas, W Quiñones, C Carrasco-López, JL Concepción, F Albericio, ... Parasitology research 101, 1511-1516, 2007 | 125 | 2007 |
Inhibition of Trypanosoma cruzi Hexokinase by Bisphosphonates MP Hudock, CE Sanz-Rodriguez, Y Song, JMW Chan, Y Zhang, S Odeh, ... Journal of medicinal chemistry 49 (1), 215-223, 2006 | 99 | 2006 |
Inhibition of Trypanosoma cruzi growth in vitro by Solanum alkaloids: a comparison with ketoconazole B Chataing, JL Concepción, R Lobaton, A Usubillaga Planta medica 64 (01), 31-36, 1998 | 99 | 1998 |
Molecular and biochemical characterization of hexokinase from Trypanosoma cruzi AJ Cáceres, R Portillo, H Acosta, D Rosales, W Quiñones, L Avilan, ... Molecular and biochemical parasitology 126 (2), 251-262, 2003 | 95 | 2003 |
Extracellular functions of glycolytic enzymes of parasites: unpredicted use of ancient proteins A Gómez-Arreaza, H Acosta, W Quiñones, JL Concepción, PAM Michels, ... Molecular and biochemical parasitology 193 (2), 75-81, 2014 | 94 | 2014 |
In Vitro Activities of ER-119884 and E5700, Two Potent Squalene Synthase Inhibitors, against Leishmania amazonensis: Antiproliferative, Biochemical, and … JC Fernandes Rodrigues, JL Concepcion, C Rodrigues, A Caldera, ... Antimicrobial agents and chemotherapy 52 (11), 4098-4114, 2008 | 93 | 2008 |
Bisphosphonates as inhibitors of Trypanosoma cruzi hexokinase: kinetic and metabolic studies CE Sanz-Rodríguez, JL Concepcion, S Pekerar, E Oldfield, JA Urbina Journal of Biological Chemistry 282 (17), 12377-12387, 2007 | 89 | 2007 |
Pyruvate phosphate dikinase and pyrophosphate metabolism in the glycosome of Trypanosoma cruzi epimastigotes H Acosta, M Dubourdieu, W Quiñones, A Cáceres, F Bringaud, ... Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2004 | 76 | 2004 |
3-Hydroxy-3-methyl-glutaryl-CoA Reductase inTrypanosoma (Schizotrypanum) cruzi: Subcellular Localization and Kinetic Properties JL Concepcion, D Gonzalez-Pacanowska, JA Urbina Archives of biochemistry and biophysics 352 (1), 114-120, 1998 | 70 | 1998 |
Mechanism of Action of 4-Phenoxyphenoxyethyl Thiocyanate (WC-9) against Trypanosoma cruzi, the Causative Agent of Chagas’ Disease JA Urbina, JL Concepcion, A Montalvetti, JB Rodriguez, R Docampo Antimicrobial agents and chemotherapy 47 (6), 2047-2050, 2003 | 66 | 2003 |
Estudio seroepidemiológico y entomológico sobre la enfermedad de Chagas en un área infestada por Triatoma maculata (Erichson 1848) en el centro-occidente de Venezuela ME Rojas, P Várquez, MF Villarreal, C Velandia, L Vergara, ... Cadernos de Saúde Pública 24 (10), 2323-2333, 2008 | 64 | 2008 |
Leishmania mexicana: molecular cloning and characterization of enolase W Quiñones, P Peña, M Domingo-Sananes, A Cáceres, PAM Michels, ... Experimental parasitology 116 (3), 241-251, 2007 | 61 | 2007 |
Molecular and biochemical characterization of novel glucokinases from Trypanosoma cruzi and Leishmania spp. AJ Cáceres, W Quiñones, M Gualdrón, A Cordeiro, L Avilán, PAM Michels, ... Molecular and biochemical parasitology 156 (2), 235-245, 2007 | 58 | 2007 |
The glycosome membrane of Trypanosoma cruzi epimastigotes: protein and lipid composition W Quiñones, JA Urbina, M Dubourdieu, JL Concepción Experimental parasitology 106 (3-4), 135-149, 2004 | 55 | 2004 |
Glycosomal targets for anti-trypanosomatid drug discovery X Barros-Alvarez, M Gualdron-Lopez, H Acosta, AJ Caceres, ... Current medicinal chemistry 21 (15), 1679-1706, 2014 | 52 | 2014 |