Leucine-rich repeat kinase 2 (LRRK2) pharmacological inhibition abates α-synuclein gene-induced neurodegeneration JPL Daher, HA Abdelmotilib, X Hu, LA Volpicelli-Daley, MS Moehle, ... Journal of Biological Chemistry 290 (32), 19433-19444, 2015 | 212 | 2015 |
G2019S-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons LA Volpicelli-Daley, H Abdelmotilib, Z Liu, L Stoyka, JPL Daher, ... Journal of Neuroscience 36 (28), 7415-7427, 2016 | 195 | 2016 |
α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration H Abdelmotilib, T Maltbie, V Delic, Z Liu, X Hu, KB Fraser, MS Moehle, ... Neurobiology of disease 105, 84-98, 2017 | 170 | 2017 |
The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins MS Moehle, JPL Daher, TD Hull, R Boddu, HA Abdelmotilib, J Mobley, ... Human molecular genetics 24 (15), 4250-4267, 2015 | 79 | 2015 |
Sensitivity and specificity of Phospho‐Ser129 α‐synuclein monoclonal antibodies V Delic, S Chandra, H Abdelmotilib, T Maltbie, S Wang, D Kem, HJ Scott, ... Journal of Comparative Neurology 526 (12), 1978-1990, 2018 | 67 | 2018 |
Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain E Xu, R Boddu, HA Abdelmotilib, A Sokratian, K Kelly, Z Liu, N Bryant, ... Molecular Neurodegeneration 17, 1-19, 2022 | 47 | 2022 |
COVID-19-associated necrotizing encephalopathy presenting without active respiratory symptoms: a case report with histopathology LA Rettenmaier, L Abdel-Wahed, H Abdelmotilib, KS Conway, ... Journal of neurovirology 28 (1), 172-176, 2022 | 12 | 2022 |
Genetic background influences LRRK2-mediated Rab phosphorylation in the rat brain K Kelly, A Chang, L Hastings, H Abdelmotilib, AB West Brain research 1759, 147372, 2021 | 10 | 2021 |
Breathing new life into an old target: pulmonary disease drugs for Parkinson’s disease therapy H Abdelmotilib, AB West Genome Medicine 9, 1-3, 2017 | 7 | 2017 |
Cortical alpha-synuclein preformed fibrils do not affect interval timing in mice Q Zhang, H Abdelmotilib, T Larson, C Keomanivong, M Conlon, ... Neuroscience letters 765, 136273, 2021 | 5 | 2021 |
Corrigendum to" α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration"[Neurobiol. Dis., Volume 105 (2017) Article 84, 98] H Abdelmotilib, T Maltbie, V Delic, Z Liu, X Hu, KB Fraser, MS Moehle, ... Neurobiology of disease 159, 105506, 2021 | 1 | 2021 |
Pathologic α-Synuclein Species Activate LRRK2 in Pro-Inflammatory Monocyte and Macrophage Responses E Xu, R Boddu, HA Abdelmotilib, K Kelly, A Sokratian, AS Harms, ... bioRxiv, 2020.05. 04.077065, 2020 | 1 | 2020 |
Alpha-Synuclein Pre-Formed Fibrils Injected into Prefrontal Cortex Primarily Spread to Cortical and Subcortical Structures MA Weber, G Kerr, R Thangavel, MM Conlon, SB Gumusoglu, K Gupta, ... Journal of Parkinson's disease, 1-14, 2024 | | 2024 |
G2019S-LRRK2 Expression Augments a-Synuclein Sequestration into Inclusions in Neurons (vol 36, pg 7415, 2016) LA Volpicelli-Daley, H Abdelmotilib, ZLL Stoyka, JPL Daher, ... JOURNAL OF NEUROSCIENCE 42 (4), 718-718, 2022 | | 2022 |
alpha-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration (vol 105, 84, 98, 2017) H Abdelmotilib, T Maltbie, V Delic, Z Liu, X Hu, KB Fraser, MS Moehle, ... NEUROBIOLOGY OF DISEASE 159, 2021 | | 2021 |
Mechanisms Of Leucine-Rich Repeat Kinase 2 And Alphα-Synuclein In Pathogenesis Of Parkinson Disease H Abdelmotilib | | 2018 |