A global reference for human genetic variation 1000 Genomes Project Consortium Nature 526 (7571), 68, 2015 | 15614 | 2015 |
Drug transporters in drug efficacy and toxicity MK DeGorter, CQ Xia, JJ Yang, RB Kim Annual review of pharmacology and toxicology 52 (1), 249-273, 2012 | 421 | 2012 |
Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care MK DeGorter, RG Tirona, UI Schwarz, YH Choi, GK Dresser, N Suskin, ... Circulation: Cardiovascular Genetics 6 (4), 400-408, 2013 | 213 | 2013 |
Uganda genome resource enables insights into population history and genomic discovery in Africa D Gurdasani, T Carstensen, S Fatumo, G Chen, CS Franklin, ... Cell 179 (4), 984-1002. e36, 2019 | 181 | 2019 |
Multiple causal variants underlie genetic associations in humans NS Abell, MK DeGorter, MJ Gloudemans, E Greenwald, KS Smith, Z He, ... Science 375 (6586), 1247-1254, 2022 | 120 | 2022 |
Trimethylamine-N-oxide: A Novel Biomarker for the Identification of Inflammatory Bowel Disease A Wilson, WA Teft, BL Morse, YH Choi, S Woolsey, MK DeGorter, ... Digestive diseases and sciences 60, 3620-3630, 2015 | 93 | 2015 |
Clarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet response IY Gong, N Crown, CM Suen, UI Schwarz, GK Dresser, MJ Knauer, ... European heart journal 33 (22), 2856-2864, 2012 | 91 | 2012 |
Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1) MK DeGorter, G Conseil, RG Deeley, RL Campbell, SPC Cole Biochemical and biophysical research communications 365 (1), 29-34, 2008 | 81 | 2008 |
Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3) CE Grant, M Gao, MK DeGorter, SPC Cole, RG Deeley Drug metabolism and disposition 36 (12), 2571-2581, 2008 | 58 | 2008 |
The transfer of pravastatin in the dually perfused human placenta J Zarek, MK DeGorter, A Lubetsky, RB Kim, CA Laskin, H Berger, G Koren Placenta 34 (8), 719-721, 2013 | 44 | 2013 |
FIRE: functional inference of genetic variants that regulate gene expression NM Ioannidis, JR Davis, MK DeGorter, NB Larson, SK McDonnell, ... Bioinformatics 33 (24), 3895-3901, 2017 | 39 | 2017 |
Interaction of three regiospecific amino acid residues is required for OATP1B1 gain of OATP1B3 substrate specificity MK DeGorter, RH Ho, BF Leake, RG Tirona, RB Kim Molecular pharmaceutics 9 (4), 986-995, 2012 | 38 | 2012 |
A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice R Sibilano, N Gaudenzio, MK DeGorter, LL Reber, JD Hernandez, ... Nature communications 7 (1), 13696, 2016 | 37 | 2016 |
Disposition of atorvastatin, rosuvastatin, and simvastatin in Oatp1b2‐/‐mice and intraindividual variability in human subjects MK DeGorter, BL Urquhart, U Gradhand, RG Tirona, RB Kim The Journal of Clinical Pharmacology 52 (11), 1689-1697, 2012 | 37 | 2012 |
Hepatic drug transporters, old and new: pharmacogenomics, drug response, and clinical relevance MK DeGorter, RB Kim Hepatology 50 (4), 1014-1016, 2009 | 21 | 2009 |
Use of transgenic and knockout mouse models to assess solute carrier transporter function MK DeGorter, RB Kim Clinical Pharmacology & Therapeutics 89 (4), 612-616, 2011 | 18 | 2011 |
Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans A Gottlieb, R Daneshjou, M DeGorter, S Bourgeois, PJ Svensson, ... Genome Medicine 9, 1-9, 2017 | 14 | 2017 |
Africa-specific human genetic variation near CHD1L associates with HIV-1 load PJ McLaren, I Porreca, G Iaconis, HP Mok, S Mukhopadhyay, E Karakoc, ... Nature 620 (7976), 1025-1030, 2023 | 11 | 2023 |
Efficacy and plasma drug concentrations with nondaily dosing of rosuvastatin AS Goldberg, MK DeGorter, MR Ban, RB Kim, RA Hegele Canadian Journal of Cardiology 29 (8), 915-919, 2013 | 10 | 2013 |
Incremental lowering of low-density lipoprotein cholesterol with ezetimibe 20 mg vs 10 mg daily in patients receiving concomitant statin therapy A Ziada, UI Schwarz, MK DeGorter, RG Tirona, MR Ban, RB Kim, ... Canadian Journal of Cardiology 29 (11), 1395-1399, 2013 | 7 | 2013 |