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Damian Yap
Damian Yap
University of British Columbia
Verified email at bccrc.ca - Homepage
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Cited by
Cited by
Year
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ...
Nature 486 (7403), 395-399, 2012
22702012
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
RD Morin, NA Johnson, TM Severson, AJ Mungall, J An, R Goya, JE Paul, ...
Nature genetics 42 (2), 181-185, 2010
19572010
PyClone: statistical inference of clonal population structure in cancer
A Roth, J Khattra, D Yap, A Wan, E Laks, J Biele, G Ha, S Aparicio, ...
Nature methods 11 (4), 396-398, 2014
9482014
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
DB Yap, J Chu, T Berg, M Schapira, SWG Cheng, A Moradian, RD Morin, ...
Blood, The Journal of the American Society of Hematology 117 (8), 2451-2459, 2011
7062011
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ...
Nature 518 (7539), 422-426, 2015
6542015
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ...
Nature communications 8 (1), 14432, 2017
4722017
TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data
G Ha, A Roth, J Khattra, J Ho, D Yap, LM Prentice, N Melnyk, ...
Genome research 24 (11), 1881-1893, 2014
3952014
Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer
A McPherson, A Roth, E Laks, T Masud, A Bashashati, AW Zhang, G Ha, ...
Nature genetics 48 (7), 758-767, 2016
3402016
Histological transformation and progression in follicular lymphoma: a clonal evolution study
R Kridel, FC Chan, A Mottok, M Boyle, P Farinha, K Tan, B Meissner, ...
PLoS medicine 13 (12), e1002197, 2016
2302016
Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage
JK Hsieh, D Yap, DJ O’Connor, V Fogal, L Fallis, F Chan, S Zhong, X Lu
Molecular and cellular biology 22 (1), 78-93, 2002
1462002
mdm2: a bridge over the two tumour suppressors, p53 and Rb
D Yap, JK Hsieh, FSG Chan, X Lu
Oncogene 18 (53), 7681-7689, 1999
1431999
Clonal genotype and population structure inference from single-cell tumor sequencing
A Roth, A McPherson, E Laks, J Biele, D Yap, A Wan, MA Smith, ...
Nature methods 13 (7), 573-576, 2016
1222016
Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation
M Heuser, DB Yap, M Leung, TR de Algara, A Tafech, S McKinney, ...
Blood, The Journal of the American Society of Hematology 113 (7), 1432-1443, 2009
1182009
A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis
T Berg, S Thoene, D Yap, T Wee, N Schoeler, P Rosten, E Lim, M Bilenky, ...
Blood, The Journal of the American Society of Hematology 123 (25), 3914-3924, 2014
1032014
Ser392 phosphorylation regulates the oncogenic function of mutant p53
DBS Yap, JK Hsieh, S Zhong, V Heath, B Gusterson, T Crook, X Lu
Cancer research 64 (14), 4749-4754, 2004
1002004
The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type
Y Wang, SY Chen, AN Karnezis, S Colborne, ND Santos, JD Lang, ...
The Journal of pathology 242 (3), 371-383, 2017
972017
ASPP1 and ASPP2 are new transcriptional targets of E2F
V Fogal, NN Kartasheva, G Trigiante, S Llanos, D Yap, KH Vousden, X Lu
Cell Death & Differentiation 12 (4), 369-376, 2005
872005
Weaver syndrome‐associated EZH2 protein variants show impaired histone methyltransferase function in vitro
ASA Cohen, DB Yap, MES Lewis, C Chijiwa, MA Ramos‐Arroyo, ...
Human mutation 37 (3), 301-307, 2016
782016
The oncogenic roles of DICER1 RNase IIIb domain mutations in ovarian Sertoli-Leydig cell tumors
Y Wang, J Chen, W Yang, F Mo, J Senz, D Yap, MS Anglesio, B Gilks, ...
Neoplasia 17 (8), 650-660, 2015
692015
A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation
A Burleigh, S McKinney, J Brimhall, D Yap, P Eirew, S Poon, V Ng, A Wan, ...
Breast Cancer Research 17, 1-21, 2015
582015
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