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Azin Sayad
Azin Sayad
Princess Margaret Cancer Centre, University Health Network
Verified email at uhnresearch.ca
Title
Cited by
Cited by
Year
The spliceosome is a therapeutic vulnerability in MYC-driven cancer
TYT Hsu, LM Simon, NJ Neill, R Marcotte, A Sayad, CS Bland, ...
Nature 525 (7569), 384-388, 2015
4532015
Functional genomic landscape of human breast cancer drivers, vulnerabilities, and resistance
R Marcotte, A Sayad, KR Brown, F Sanchez-Garcia, J Reimand, M Haider, ...
Cell 164 (1), 293-309, 2016
4492016
Essential gene profiles in breast, pancreatic, and ovarian cancer cells
R Marcotte, KR Brown, F Suarez, A Sayad, K Karamboulas, ...
Cancer discovery 2 (2), 172-189, 2012
3752012
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
J Petschnigg, B Groisman, M Kotlyar, M Taipale, Y Zheng, CF Kurat, ...
Nature methods 11 (5), 585-592, 2014
1942014
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities
FJ Vizeacoumar, R Arnold, FS Vizeacoumar, M Chandrashekhar, ...
Molecular systems biology 9 (1), 696, 2013
1082013
Essential gene profiles in breast, pancreatic, and ovarian cancer cells. Cancer Discov. 2012; 2: 172–189. doi: 10.1158/2159-8290
R Marcotte, KR Brown, F Suarez, A Sayad, K Karamboulas, ...
CD-11-0224.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 2012
642012
COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines
JLY Koh, KR Brown, A Sayad, D Kasimer, T Ketela, J Moffat
Nucleic acids research 40 (D1), D957-D963, 2012
622012
High expression of B7-H3 on stromal cells defines tumor and stromal compartments in epithelial ovarian cancer and is associated with limited immune activation
HL MacGregor, A Sayad, A Elia, BX Wang, SR Katz, PA Shaw, BA Clarke, ...
Journal for ImmunoTherapy of Cancer 7, 1-17, 2019
582019
Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer
CA Chang, J Jen, S Jiang, A Sayad, AS Mer, KR Brown, AML Nixon, ...
Cancer discovery 12 (4), 1022-1045, 2022
562022
SHP2 is required for BCR-ABL1-induced hematologic neoplasia
S Gu, A Sayad, G Chan, W Yang, Z Lu, C Virtanen, RA Van Etten, ...
Leukemia 32 (1), 203-213, 2018
412018
Coenzyme A fuels T cell anti-tumor immunity
MS Paul, SD Saibil, SJ Han, K Israni-Winger, SC Lien, RC Laister, ...
Cell metabolism 33 (12), 2415-2427. e6, 2021
372021
IL6 Induces an IL22+ CD8+ T-cell Subset with Potent Antitumor Function
M St. Paul, SD Saibil, SC Lien, SJ Han, A Sayad, DT Mulder, ...
Cancer immunology research 8 (3), 321-333, 2020
322020
Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer
HL MacGregor, C Garcia-Batres, A Sayad, A Elia, HK Berman, A Toker, ...
Oncoimmunology 8 (12), e1665460, 2019
312019
Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1
S Gu, WW Chan, G Mohi, J Rosenbaum, A Sayad, Z Lu, C Virtanen, S Li, ...
Blood, The Journal of the American Society of Hematology 127 (14), 1803-1813, 2016
302016
A genomically characterized collection of high-grade serous ovarian cancer xenografts for preclinical testing
P Cybulska, JM Stewart, A Sayad, C Virtanen, PA Shaw, B Clarke, ...
The American Journal of Pathology 188 (5), 1120-1131, 2018
252018
Computational modeling of ovarian cancer dynamics suggests optimal strategies for therapy and screening
S Gu, S Lheureux, A Sayad, P Cybulska, L Hogen, I Vyarvelska, D Tu, ...
Proceedings of the National Academy of Sciences 118 (25), e2026663118, 2021
132021
Overproduction of IFNγ by Cbl-b–Deficient CD8+ T Cells Provides Resistance against Regulatory T Cells and Induces Potent Antitumor Immunity
SJ Han, ZQ Liu, DC Chung, MS Paul, CR Garcia-Batres, A Sayad, ...
Cancer Immunology Research 10 (4), 437-452, 2022
82022
Integrated genomic, transcriptomic, and RNA-interference analysis of genes in somatic copy number gains in pancreatic ductal adenocarcinoma
N Samuel, A Sayad, G Wilson, M Lemire, KR Brown, L Muthuswamy, ...
Pancreas 42 (6), 1016-1026, 2013
82013
A Biochemical Genomics Screen for Substrates of Ste20p Kinase Enables the In Silico Prediction of Novel Substrates
RB Annan, AY Lee, ID Reid, A Sayad, M Whiteway, M Hallett, DY Thomas
Plos one 4 (12), e8279, 2009
52009
Functional genomic landscape of human breast resource functional genomic landscape of human breast cancer drivers, vulnerabilities, and resistance
R Marcotte, A Sayad, KR Brown, D Pe, J Moffat, BG Neel
Cell 164, 293-309, 2016
42016
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