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Dr James C McConnell
Dr James C McConnell
Senior Scientist, Epistem Limited
Verified email at epistem.co.uk
Title
Cited by
Cited by
Year
Growth differentiation factor 6 and transforming growth factor-beta differentially mediate mesenchymal stem cell differentiation, composition, and micromechanical properties of …
LE Clarke, JC McConnell, MJ Sherratt, B Derby, SM Richardson, ...
Arthritis research & therapy 16, 1-13, 2014
1712014
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
R Eyre, DG Alférez, A Santiago-Gómez, K Spence, JC McConnell, C Hart, ...
Nature communications 10 (1), 5016, 2019
1152019
Increased peri-ductal collagen micro-organization may contribute to raised mammographic density
JC McConnell, OV O’Connell, K Brennan, L Weiping, M Howe, L Joseph, ...
Breast Cancer Research 18, 1-17, 2016
1072016
Global LINE-1 DNA methylation is associated with blood glycaemic and lipid profiles
MS Pearce, JC McConnell, C Potter, LM Barrett, L Parker, JC Mathers, ...
International journal of epidemiology 41 (1), 210-217, 2012
1062012
Cellular mechano-environment regulates the mammary circadian clock
N Yang, J Williams, V Pekovic-Vaughan, P Wang, S Olabi, J McConnell, ...
Nature communications 8 (1), 14287, 2017
1042017
Raised mammographic density: causative mechanisms and biological consequences
MJ Sherratt, JC McConnell, CH Streuli
Breast Cancer Research 18, 1-9, 2016
812016
The dynamic nature of hypertrophic and fibrotic remodeling of the fish ventricle
AN Keen, AJ Fenna, JC McConnell, MJ Sherratt, P Gardner, HA Shiels
Frontiers in Physiology 6, 427, 2016
692016
Lysyl oxidase–like 2 (LOXL2)–mediated cross-linking of tropoelastin
CEH Schmelzer, A Heinz, H Troilo, MP Lockhart-Cairns, TA Jowitt, ...
The FASEB Journal 33 (4), 5468, 2019
672019
Organization of the dermal matrix impacts the biomechanical properties of skin
AK Langton, HK Graham, JC McConnell, MJ Sherratt, CEM Griffiths, ...
British Journal of Dermatology 177 (3), 818-827, 2017
632017
Skin aging: molecular pathology, dermal remodelling and the imaging revolution
VL Newton, JC Mcconnell, SA Hibbert, HK Graham, RE Watson
G Ital Dermatol Venereol 150 (6), 665-674, 2015
592015
How stiff is skin?
HK Graham, JC McConnell, G Limbert, MJ Sherratt
Experimental dermatology 28, 4-9, 2019
442019
Disrupted circadian clocks and altered tissue mechanics in primary human breast tumours
E Broadberry, J McConnell, J Williams, N Yang, E Zindy, A Leek, ...
Breast Cancer Research 20, 1-13, 2018
282018
Macro-and micromechanical remodelling in the fish atrium is associated with regulation of collagen 1 alpha 3 chain expression
AN Keen, AJ Fenna, JC McConnell, MJ Sherratt, P Gardner, HA Shiels
Pflügers Archiv-European Journal of Physiology 470, 1205-1219, 2018
142018
Bioinformatic selection of putative epigenetically regulated loci associated with obesity using gene expression data
V Turcot, A Groom, JC McConnell, MS Pearce, C Potter, ND Embleton, ...
Gene 499 (1), 99-107, 2012
82012
Restoration of collagen and elastic fibre networks following treatment of photoaged skin with Serènesse, a novel over‐the‐counter anti‐ageing product
AK Langton, JC McConnell, LF Cotterell, P Halai, TW Griffiths, ...
Journal of the European Academy of Dermatology and Venereology 36 (1), e43-e46, 2022
2022
Targeting IL-1 beta-Wnt signalling to prevent breast cancer colonisation in the bone microenvironment
R Eyre, D Alferez, A Santiago-Gomez, K Spence, J McConnell, B Simoes, ...
Clinical and Experimental Metastasis 34 (8), 493-493, 2017
2017
Activation of SMAD2 upon compressive load occurs exclusively in regions of cartilage where matrix stiffness is relatively low
X Tang, HK Graham, B Derby, MJ Sherratt, J McConnell, TL Vincent
Osteoarthritis and Cartilage 24, S152, 2016
2016
Hypoxia and Load Enhances GDF6 Driven Discogenic Mesenchymal Stem Cell Differentiation But Alters Matrix Composition in Tissue Engineered Nucleus Pulposus Constructs
LE Clarke, JC McConnell, MJ Sherratt, SM Richardson, JA Hoyland
TISSUE ENGINEERING PART A 21, S310-S310, 2015
2015
High mammographic density is associated with deposition of organised fibrillar collagen and increased stiffness in periductal breast stroma
A Gandhi, CC Kirwan, JC McConnell, OV O'Connell, MJ Sherratt, ...
CANCER RESEARCH 75 (9), 2015
2015
Epigenetic mechanisms in the early life programming of obesity
JC McConnell
Newcastle University, 2012
2012
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Articles 1–20