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J Bhandari
J Bhandari
Verified email at mcmaster.ca
Title
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Year
Brain targeting of a water insoluble antipsychotic drug haloperidol via the intranasal route using PAMAM dendrimer
YK Katare, RP Daya, C Sookram Gray, RE Luckham, J Bhandari, ...
Molecular pharmaceutics 12 (9), 3380-3388, 2015
1032015
Haloperidol-loaded intranasally administered lectin functionalized poly (ethylene glycol)–block-poly (d, l)-lactic-co-glycolic acid (PEG–PLGA) nanoparticles for the treatment …
J Piazza, T Hoare, L Molinaro, K Terpstra, J Bhandari, ...
European Journal of Pharmaceutics and Biopharmaceutics 87 (1), 30-39, 2014
942014
Intranasal delivery of antipsychotic drugs
YK Katare, JE Piazza, J Bhandari, RP Daya, K Akilan, MJ Simpson, ...
Schizophrenia Research 184, 2-13, 2017
562017
Effects of the dopamine D2 allosteric modulator, PAOPA, on the expression of GRK2, arrestin-3, ERK1/2, and on receptor internalization
D Basu, Y Tian, J Bhandari, JR Jiang, P Hui, RL Johnson, RK Mishra
PLoS One 8 (8), e70736, 2013
222013
Improvements and important considerations for the 5-choice serial reaction time task—An effective measurement of visual attention in rats
J Bhandari, R Daya, RK Mishra
Journal of Neuroscience Methods 270, 17-29, 2016
192016
Effects of MK-801 treatment across several pre-clinical analyses including a novel assessment of brain metabolic function utilizing PET and CT fused imaging in live rats
RP Daya, JK Bhandari, PA Hui, Y Tian, T Farncombe, RK Mishra
Neuropharmacology 77, 325-333, 2014
182014
The dopamine allosteric agent, PAOPA, demonstrates therapeutic potential in the phencyclidine NMDA pre-clinical rat model of schizophrenia
RP Daya, J Bhandari, SK Kooner, J Ho, CD Rowley, NA Bock, ...
Frontiers in Behavioral Neuroscience 12, 302, 2018
92018
Change in expression of vesicular protein synapsin II by chronic treatment with D2 allosteric modulator PAOPA
D Basu, Y Tian, P Hui, J Bhandari, RL Johnson, RK Mishra
Peptides 66, 58-62, 2015
22015
Effect of Chronic Treatment with D2 Allosteric Modulator PAOPA on the Expression of Cerebral Dopamine Neurotrophic Factor (CDNF) in Select Brain Regions
Y Tian, R Daya, J Bhandari, H Joshi, S Thomson, V Patel, R Mishra
International Journal of Peptide Research and Therapeutics 27 (4), 2551-2557, 2021
2021
The Effect of PAOPA, a Novel Allosteric Modulator of Dopamine D2 Receptors, on Signaling Proteins Following Sub-Chronic Administration in Rats
R Daya, J Ho, S Thomson, J Bhandari, RK Mishra
Current Molecular Pharmacology 14 (4), 469-476, 2021
2021
Characterizing the cognitive, behavioural, and mechanistic actions of novel allosteric modulator PAOPA for the treatment of schizophrenia
J Bhandari
2015
Compound 186 is a Negative Allosteric Modulator of Dopamine D2 Receptors: Implications for Improving Schizophrenia Therapy
J Bhandari, J Mah, R Daya, RL Johnson, RK Mishra
The Meducator 1 (22), 2012
2012
PAMAM dendrimer based formulation of haloperidol for brain targeting via intranasal delivery
YK Katare, RP Daya, C Sookram, R Luckham, J Bhandari, AS Chauhan, ...
MACABSTRACTS
R dAMAgEd AdulT SEnSoRy nEuRonS In, S ThERApy
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