|Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase|
Y Buganim, DA Faddah, AW Cheng, E Itskovich, S Markoulaki, K Ganz, ...
Cell 150 (6), 1209-1222, 2012
|Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling|
G Sahay, W Querbes, C Alabi, A Eltoukhy, S Sarkar, C Zurenko, ...
Nature biotechnology 31 (7), 653, 2013
|Mechanisms and models of somatic cell reprogramming|
Y Buganim, DA Faddah, R Jaenisch
Nature Reviews Genetics 14 (6), 427, 2013
|Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells|
BW Carey, S Markoulaki, JH Hanna, DA Faddah, Y Buganim, J Kim, ...
Cell stem cell 9 (6), 588-598, 2011
|p53‐repressed miRNAs are involved with E2F in a feed‐forward loop promoting proliferation|
R Brosh, R Shalgi, A Liran, G Landan, K Korotayev, GH Nguyen, E Enerly, ...
Molecular systems biology 4 (1), 2008
|Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease|
S Sarkar, B Carroll, Y Buganim, D Maetzel, AHM Ng, JP Cassady, ...
Cell reports 5 (5), 1302-1315, 2013
|Mutant p53R175H upregulates Twist1 expression and promotes epithelial–mesenchymal transition in immortalized prostate cells|
I Kogan-Sakin, Y Tabach, Y Buganim, A Molchadsky, H Solomon, ...
Cell death and differentiation 18 (2), 271, 2011
|Direct reprogramming of fibroblasts into embryonic Sertoli-like cells by defined factors|
Y Buganim, E Itskovich, YC Hu, AW Cheng, K Ganz, S Sarkar, D Fu, ...
Cell stem cell 11 (3), 373-386, 2012
|The developmental potential of iPSCs is greatly influenced by reprogramming factor selection|
Y Buganim, S Markoulaki, N van Wietmarschen, H Hoke, T Wu, K Ganz, ...
Cell stem cell 15 (3), 295-309, 2014
|Single-cell analysis reveals that expression of nanog is biallelic and equally variable as that of other pluripotency factors in mouse ESCs|
DA Faddah, H Wang, AW Cheng, Y Katz, Y Buganim, R Jaenisch
Cell stem cell 13 (1), 23-29, 2013
|Mutant p53 attenuates the SMAD-dependent transforming growth factor β1 (TGF-β1) signaling pathway by repressing the expression of TGF-β receptor type II|
E Kalo, Y Buganim, KE Shapira, H Besserglick, N Goldfinger, L Weisz, ...
Molecular and cellular biology 27 (23), 8228-8242, 2007
|Amplification of the 20q chromosomal arm occurs early in tumorigenic transformation and may initiate cancer|
Y Tabach, I Kogan-Sakin, Y Buganim, H Solomon, N Goldfinger, ...
PloS one 6 (1), e14632, 2011
|Wide-scale analysis of human functional transcription factor binding reveals a strong bias towards the transcription start site|
Y Tabach, R Brosh, Y Buganim, A Reiner, O Zuk, A Yitzhaky, M Koudritsky, ...
PloS one 2 (8), e807, 2007
|Modulated expression of WFDC1 during carcinogenesis and cellular senescence|
S Madar, R Brosh, Y Buganim, O Ezra, I Goldstein, H Solomon, I Kogan, ...
Carcinogenesis 30 (1), 20-27, 2008
|Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect|
M Milyavsky, I Shats, A Cholostoy, R Brosh, Y Buganim, L Weisz, I Kogan, ...
Cancer cell 11 (2), 133-146, 2007
|Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species|
E Kalo, I Kogan-Sakin, H Solomon, E Bar-Nathan, M Shay, Y Shetzer, ...
J Cell Sci 125 (22), 5578-5586, 2012
|Transcriptional programs following genetic alterations in p53, INK4A, and H-Ras genes along defined stages of malignant transformation|
M Milyavsky, Y Tabach, I Shats, N Erez, Y Cohen, X Tang, M Kalis, ...
Cancer Research 65 (11), 4530-4543, 2005
|Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1|
I Kogan-Sakin, M Cohen, N Paland, S Madar, H Solomon, A Molchadsky, ...
Carcinogenesis 30 (4), 698-705, 2009
|p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity|
A Molchadsky, O Ezra, PG Amendola, D Krantz, I Kogan-Sakin, ...
Cell death and differentiation 20 (5), 774, 2013
|Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature|
H Solomon, Y Buganim, I Kogan-Sakin, L Pomeraniec, Y Assia, S Madar, ...
J Cell Sci 125 (13), 3144-3152, 2012