Jean M Macklaim, PhD
Jean M Macklaim, PhD
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Microbiome datasets are compositional: and this is not optional
GB Gloor, JM Macklaim, V Pawlowsky-Glahn, JJ Egozcue
Frontiers in microbiology 8, 2224, 2017
Unifying the analysis of high-throughput sequencing datasets: characterizing RNA-seq, 16S rRNA gene sequencing and selective growth experiments by compositional data analysis
AD Fernandes, JN Reid, JM Macklaim, TA McMurrough, DR Edgell, ...
Microbiome 2 (1), 1-13, 2014
Microbiome profiling by illumina sequencing of combinatorial sequence-tagged PCR products
GB Gloor, R Hummelen, JM Macklaim, RJ Dickson, AD Fernandes, ...
PLoS One 5 (10), e15406, 2010
Microbiota of human breast tissue
C Urbaniak, J Cummins, M Brackstone, JM Macklaim, GB Gloor, ...
Applied and environmental microbiology 80 (10), 3007-3014, 2014
Deep sequencing of the vaginal microbiota of women with HIV
R Hummelen, AD Fernandes, JM Macklaim, RJ Dickson, J Changalucha, ...
PloS one 5 (8), e12078, 2010
Comparative meta-RNA-seq of the vaginal microbiota and differential expression by Lactobacillus iners in health and dysbiosis
JM Macklaim, AD Fernandes, JM Di Bella, JA Hammond, G Reid, ...
Microbiome 1 (1), 1-11, 2013
ANOVA-like differential expression (ALDEx) analysis for mixed population RNA-Seq
AD Fernandes, JM Macklaim, TG Linn, G Reid, GB Gloor
PLoS One 8 (7), e67019, 2013
At the crossroads of vaginal health and disease, the genome sequence of Lactobacillus iners AB-1
JM Macklaim, GB Gloor, KC Anukam, S Cribby, G Reid
Proceedings of the National Academy of Sciences 108 (Supplement 1), 4688-4695, 2011
Vaginal microbiome and epithelial gene array in post-menopausal women with moderate to severe dryness
R Hummelen, JM Macklaim, JE Bisanz, JA Hammond, A McMillan, ...
PloS one 6 (11), e26602, 2011
Changes in vaginal microbiota following antimicrobial and probiotic therapy
JM Macklaim, JC Clemente, R Knight, GB Gloor, G Reid
Microbial ecology in health and disease 26 (1), 27799, 2015
A multi-platform metabolomics approach identifies highly specific biomarkers of bacterial diversity in the vagina of pregnant and non-pregnant women
A McMillan, S Rulisa, M Sumarah, JM Macklaim, J Renaud, JE Bisanz, ...
Scientific reports 5 (1), 1-14, 2015
Microbiota at multiple body sites during pregnancy in a rural Tanzanian population and effects of Moringa-supplemented probiotic yogurt
JE Bisanz, MK Enos, G PrayGod, S Seney, JM Macklaim, S Chilton, ...
Applied and environmental microbiology 81 (15), 4965-4975, 2015
Persistence of the oral probiotic Streptococcus salivarius M18 is dose dependent and megaplasmid transfer can augment their bacteriocin production and adhesion characteristics
JP Burton, PA Wescombe, JM Macklaim, MHC Chai, K MacDonald, ...
Plos one 8 (6), e65991, 2013
Adhesion of Lactobacillus iners AB-1 to human fibronectin: a key mediator for persistence in the vagina?
A McMillan, JM Macklaim, JP Burton, G Reid
Reproductive Sciences 20 (7), 791-796, 2013
Genome sequence of Lactobacillus pentosus KCA1: vaginal isolate from a healthy premenopausal woman
KC Anukam, JM Macklaim, GB Gloor, G Reid, J Boekhorst, B Renckens, ...
PloS one 8 (3), e59239, 2013
Subinhibitory antibiotic therapy alters recurrent urinary tract infection pathogenesis through modulation of bacterial virulence and host immunity
LW Goneau, TJ Hannan, RA MacPhee, DJ Schwartz, JM Macklaim, ...
MBio 6 (2), e00356-15, 2015
Responders and non-responders to probiotic interventions: How can we improve the odds?
G Reid, E Gaudier, F Guarner, GB Huffnagle, JM Macklaim, AM Munoz, ...
Gut Microbes 1 (3), 200, 2010
Compositional uncertainty should not be ignored in high-throughput sequencing data analysis
GB Gloor, JM Macklaim, M Vu, AD Fernandes
Austrian Journal of Statistics 45 (4), 73-87, 2016
Displaying variation in large datasets: plotting a visual summary of effect sizes
GB Gloor, JM Macklaim, AD Fernandes
Journal of Computational and Graphical Statistics 25 (3), 971-979, 2016
Exploring a road map to counter misconceptions about the cervicovaginal microbiome and disease
JM Macklaim, CR Cohen, G Donders, GB Gloor, JE Hill, GP Parham, ...
Reproductive sciences 19 (11), 1154-1162, 2012
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