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David Hildeman
David Hildeman
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Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling
LA Sena, S Li, A Jairaman, M Prakriya, T Ezponda, DA Hildeman, ...
Immunity 38 (2), 225-236, 2013
12352013
An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder
MB Jordan, D Hildeman, J Kappler, P Marrack
Blood 104 (3), 735-743, 2004
7672004
Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim
DA Hildeman, Y Zhu, TC Mitchell, P Bouillet, A Strasser, J Kappler, ...
Immunity 16 (6), 759-767, 2002
7402002
The immune cell landscape in kidneys of patients with lupus nephritis
A Arazi, DA Rao, CC Berthier, A Davidson, Y Liu, PJ Hoover, A Chicoine, ...
Nature immunology 20 (7), 902-914, 2019
5802019
Reactive oxygen species regulate activation-induced T cell apoptosis
DA Hildeman, T Mitchell, TK Teague, P Henson, BJ Day, J Kappler, ...
Immunity 10 (6), 735-744, 1999
5731999
T cells compete for access to antigen-bearing antigen-presenting cells
RM Kedl, WA Rees, DA Hildeman, B Schaefer, T Mitchell, J Kappler, ...
The Journal of experimental medicine 192 (8), 1105-1114, 2000
5352000
× Phosphorylation of Bax Ser184 by Akt Regulates Its Activity and Apoptosis in Neutrophils
SJ Gardai, DA Hildeman, SK Frankel, BB Whitlock, SC Frasch, ...
Journal of Biological Chemistry 279 (20), 21085-21095, 2004
5182004
Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation
CS Lages, I Suffia, PA Velilla, B Huang, G Warshaw, DA Hildeman, ...
The Journal of Immunology 181 (3), 1835-1848, 2008
4202008
Molecular mechanisms of activated T cell death in vivo
DA Hildeman, Y Zhu, TC Mitchell, J Kappler, P Marrack
Current opinion in immunology 14 (3), 354-359, 2002
3772002
IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis
J Unsinger, M McGlynn, KR Kasten, AS Hoekzema, E Watanabe, ...
The Journal of immunology 184 (7), 3768-3779, 2010
3752010
Nonredundant roles for B cell-derived IL-10 in immune counter-regulation
R Madan, F Demircik, S Surianarayanan, JL Allen, S Divanovic, ...
The Journal of Immunology 183 (4), 2312-2320, 2009
3342009
C5a negatively regulates toll-like receptor 4-induced immune responses
H Hawlisch, Y Belkaid, R Baelder, D Hildeman, C Gerard, J Köhl
Immunity 22 (4), 415-426, 2005
3212005
Homeostasis of αβ TCR+ T cells
P Marrack, J Bender, D Hildeman, M Jordan, T Mitchell, M Murakami, ...
Nature immunology 1 (2), 107-111, 2000
3142000
Control of Bcl-2 expression by reactive oxygen species
DA Hildeman, T Mitchell, B Aronow, S Wojciechowski, J Kappler, ...
Proceedings of the National Academy of Sciences 100 (25), 15035-15040, 2003
3042003
Immunological adjuvants promote activated T cell survival via induction of Bcl-3
TC Mitchell, D Hildeman, RM Kedl, TK Teague, BC Schaefer, J White, ...
Nature immunology 2 (5), 397-402, 2001
2922001
Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis
S Wojciechowski, P Tripathi, T Bourdeau, L Acero, HL Grimes, JD Katz, ...
The Journal of experimental medicine 204 (7), 1665-1675, 2007
2822007
Activation changes the spectrum but not the diversity of genes expressed by T cells
TK Teague, D Hildeman, RM Kedl, T Mitchell, W Rees, BC Schaefer, ...
Proceedings of the National Academy of Sciences 96 (22), 12691-12696, 1999
2801999
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells
W Pierson, B Cauwe, A Policheni, SM Schlenner, D Franckaert, J Berges, ...
Nature immunology 14 (9), 959-965, 2013
2502013
T cell apoptosis and reactive oxygen species
DA Hildeman, T Mitchell, J Kappler, P Marrack
The Journal of clinical investigation 111 (5), 575-581, 2003
2202003
Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis
TS Johnson, CE Terrell, SH Millen, JD Katz, DA Hildeman, MB Jordan
The Journal of Immunology 192 (1), 84-91, 2014
1982014
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