Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation MJ Diógenes, RB Dias, DM Rombo, HV Miranda, F Maiolino, P Guerreiro, ... Journal of Neuroscience 32 (34), 11750-11762, 2012 | 308 | 2012 |
Activation of adenosine A2A receptor facilitates brain-derived neurotrophic factor modulation of synaptic transmission in hippocampal slices MJ Diógenes, CC Fernandes, AM Sebastiao, JA Ribeiro Journal of Neuroscience 24 (12), 2905-2913, 2004 | 221 | 2004 |
Enhanced role of adenosine A2A receptors in the modulation of LTP in the rat hippocampus upon ageing AR Costenla, MJ Diógenes, PM Canas, RJ Rodrigues, C Nogueira, ... European Journal of Neuroscience 34 (1), 12-21, 2011 | 199 | 2011 |
Enhancement of LTP in aged rats is dependent on endogenous BDNF MJ Diógenes, AR Costenla, LV Lopes, A Jerónimo-Santos, VC Sousa, ... Neuropsychopharmacology 36 (9), 1823-1836, 2011 | 160 | 2011 |
Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine BM Fontinha, MJ Diógenes, JA Ribeiro, AM Sebastiao Neuropharmacology 54 (6), 924-933, 2008 | 160 | 2008 |
Influence of age on BDNF modulation of hippocampal synaptic transmission: Interplay with adenosine A2A receptors MJ Diógenes, N Assaife‐Lopes, A Pinto‐Duarte, JA Ribeiro, ... Hippocampus 17 (7), 577-585, 2007 | 122 | 2007 |
Dysregulation of TrkB receptors and BDNF function by amyloid-β peptide is mediated by calpain A Jerónimo-Santos, SH Vaz, S Parreira, S Rapaz-Lérias, AP Caetano, ... Cerebral Cortex 25 (9), 3107-3121, 2015 | 120 | 2015 |
Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice S Kemppainen, T Rantamäki, A Jeronimo-Santos, G Lavasseur, H Autio, ... Neurobiology of aging 33 (6), 1122. e23-1122. e39, 2012 | 105 | 2012 |
Chocolate consumption is associated with a lower risk of cognitive decline A Moreira, MJ Diogenes, A De Mendonça, N Lunet, H Barros Journal of Alzheimer's disease 53 (1), 85-93, 2016 | 90 | 2016 |
Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and … SL Silva, AR Vaz, MJ Diógenes, N van Rooijen, AM Sebastião, ... Neuropharmacology 62 (7), 2398-2408, 2012 | 85 | 2012 |
Purine nucleosides in neuroregeneration and neuroprotection FF Ribeiro, S Xapelli, C Miranda-Lourenco, SR Tanqueiro, ... Neuropharmacology 104, 226-242, 2016 | 76 | 2016 |
Triggering of BDNF facilitatory action on neuromuscular transmission by adenosine A2A receptors PA Pousinha, MJ Diogenes, JA Ribeiro, AM Sebastião Neuroscience letters 404 (1-2), 143-147, 2006 | 76 | 2006 |
Modulation of brain-derived neurotrophic factor (BDNF) actions in the nervous system by adenosine A2A receptors and the role of lipid rafts AM Sebastião, N Assaife-Lopes, MJ Diógenes, SH Vaz, JA Ribeiro Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (5), 1340-1349, 2011 | 73 | 2011 |
Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase MJ Diógenes, R Neves-Tomé, S Fucile, K Martinello, M Scianni, ... Cerebral cortex 24 (1), 67-80, 2014 | 72 | 2014 |
Inhibition of NMDA receptors prevents the loss of BDNF function induced by amyloid β SR Tanqueiro, RM Ramalho, TM Rodrigues, LV Lopes, AM Sebastião, ... Frontiers in pharmacology 9, 237, 2018 | 68 | 2018 |
Challenges of BDNF-based therapies: From common to rare diseases C Miranda-Lourenço, L Ribeiro-Rodrigues, J Fonseca-Gomes, ... Pharmacological Research 162, 105281, 2020 | 52 | 2020 |
In vivo bio-distribution and toxicity evaluation of polymeric and lipid-based nanoparticles: a potential approach for chronic diseases treatment J Fonseca-Gomes, JA Loureiro, SR Tanqueiro, FM Mouro, P Ruivo, ... International journal of nanomedicine, 8609-8621, 2020 | 49 | 2020 |
Adenosine kinase deficiency in the brain results in maladaptive synaptic plasticity US Sandau, M Colino-Oliveira, A Jones, B Saleumvong, SQ Coffman, ... Journal of Neuroscience 36 (48), 12117-12128, 2016 | 45 | 2016 |
Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP A Jerónimo-Santos, VL Batalha, CE Müller, Y Baqi, AM Sebastião, ... Neuropharmacology 83, 99-106, 2014 | 38 | 2014 |
Challenges and promises in the development of neurotrophic factor-based therapies for Parkinson’s disease TM Rodrigues, A Jerónimo-Santos, TF Outeiro, AM Sebastiao, ... Drugs & aging 31, 239-261, 2014 | 38 | 2014 |