Dirk M. Zajonc
Dirk M. Zajonc
Director, Cancer Immunology Discovery, Pfizer La Jolla
Verified email at pfizer.com
Cited by
Cited by
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria
Y Kinjo, E Tupin, D Wu, M Fujio, R Garcia-Navarro, MREI Benhnia, ...
Nature immunology 7 (9), 978-986, 2006
Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor
DM Zajonc, C Cantu, J Mattner, D Zhou, PB Savage, A Bendelac, ...
Nature immunology 6 (8), 810-818, 2005
Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria
Y Kinjo, P Illarionov, JL Vela, B Pei, E Girardi, X Li, Y Li, M Imamura, ...
Nature immunology 12 (10), 966-974, 2011
T cell activation by lipopeptide antigens
DB Moody, DC Young, TY Cheng, JP Rosat, C Roura-Mir, PB O'Connor, ...
Science 303 (5657), 527-531, 2004
Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 Ĺ
DM Zajonc, MA Elsliger, L Teyton, IA Wilson
Nature immunology 4 (8), 808-815, 2003
Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity
DM Zajonc, I Maricic, D Wu, R Halder, K Roy, CH Wong, V Kumar, ...
The Journal of experimental medicine 202 (11), 1517-1526, 2005
Anatomy of CD1–lipid antigen complexes
DB Moody, DM Zajonc, IA Wilson
Nature Reviews Immunology 5 (5), 387-399, 2005
The identification of the endogenous ligands of natural killer T cells reveals the presence of mammalian α-linked glycosylceramides
L Kain, B Webb, BL Anderson, S Deng, M Holt, A Costanzo, M Zhao, ...
Immunity 41 (4), 543-554, 2014
Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d
D Wu, DM Zajonc, M Fujio, BA Sullivan, Y Kinjo, M Kronenberg, IA Wilson, ...
Proceedings of the National Academy of Sciences 103 (11), 3972-3977, 2006
Mechanisms for glycolipid antigen-driven cytokine polarization by Vα14i NKT cells
BA Sullivan, NA Nagarajan, G Wingender, J Wang, I Scott, M Tsuji, ...
The journal of immunology 184 (1), 141-153, 2010
Molecular mechanism of lipopeptide presentation by CD1a
DM Zajonc, MDM Crispin, TA Bowden, DC Young, TY Cheng, J Hu, ...
Immunity 22 (2), 209-219, 2005
Type II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigens
E Girardi, I Maricic, J Wang, TT Mac, P Iyer, V Kumar, DM Zajonc
Nature immunology 13 (9), 851-856, 2012
Galactose‐modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis
S Aspeslagh, Y Li, ED Yu, N Pauwels, M Trappeniers, E Girardi, T Decruy, ...
The EMBO journal 30 (11), 2294-2305, 2011
Crystal structures of mouse CD1d-iGb3 complex and its cognate Vα14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids
DM Zajonc, PB Savage, A Bendelac, IA Wilson, L Teyton
Journal of molecular biology 377 (4), 1104-1116, 2008
Galectin-9 controls the therapeutic activity of 4-1BB–targeting antibodies
S Madireddi, SY Eun, SW Lee, I Nemčovičová, AK Mehta, DM Zajonc, ...
Journal of Experimental Medicine 211 (7), 1433-1448, 2014
Cardiolipin binds to CD1d and stimulates CD1d-restricted γδ T cells in the normal murine repertoire
M Dieudé, H Striegl, AJ Tyznik, J Wang, SM Behar, CA Piccirillo, ...
The Journal of Immunology 186 (8), 4771-4781, 2011
Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells
J Wang, Y Li, Y Kinjo, TT Mac, D Gibson, GF Painter, M Kronenberg, ...
Proceedings of the National Academy of Sciences 107 (4), 1535-1540, 2010
The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode
Y Li, E Girardi, J Wang, ED Yu, GF Painter, M Kronenberg, DM Zajonc
Journal of Experimental Medicine 207 (11), 2383-2393, 2010
Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses
W Smith, P Tomasec, R Aicheler, A Loewendorf, I Nemčovičová, ...
Cell host & microbe 13 (3), 324-335, 2013
Molecular basis of lipid antigen presentation by CD 1d and recognition by natural killer T cells
E Girardi, DM Zajonc
Immunological reviews 250 (1), 167-179, 2012
The system can't perform the operation now. Try again later.
Articles 1–20