James Bainbridge
James Bainbridge
Verified email at ucl.ac.uk
TitleCited byYear
Effect of gene therapy on visual function in Leber's congenital amaurosis
JWB Bainbridge, AJ Smith, SS Barker, S Robbie, R Henderson, ...
New England Journal of Medicine 358 (21), 2231-2239, 2008
18882008
Long-term effect of gene therapy on Leber’s congenital amaurosis
JWB Bainbridge, MS Mehat, V Sundaram, SJ Robbie, SE Barker, ...
New England Journal of Medicine 372 (20), 1887-1897, 2015
4162015
Restoration of vision after transplantation of photoreceptors
RA Pearson, AC Barber, M Rizzi, C Hippert, T Xue, EL West, Y Duran, ...
Nature 485 (7396), 99-103, 2012
3692012
Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy
RR Ali, GM Sarra, C Stephens, M De Alwis, JWB Bainbridge, PM Munro, ...
Nature genetics 25 (3), 306-310, 2000
3422000
Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina
A Gonzalez-Cordero, EL West, RA Pearson, Y Duran, LS Carvalho, ...
Nature biotechnology 31 (8), 741-747, 2013
3112013
Repair of the degenerate retina by photoreceptor transplantation
AC Barber, C Hippert, Y Duran, EL West, JWB Bainbridge, ...
Proceedings of the National Academy of Sciences 110 (1), 354-359, 2013
2092013
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling
X Wang, S Abraham, JAG McKenzie, N Jeffs, M Swire, VB Tripathi, ...
Nature 499 (7458), 306-311, 2013
2022013
In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endothelium and retinal pigment epithelium
JWB Bainbridge, C Stephens, K Parsley, C Demaison, A Halfyard, ...
Gene therapy 8 (21), 1665-1668, 2001
2022001
Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1
JWB Bainbridge, A Mistry, M De Alwis, E Paleolog, A Baker, AJ Thrasher, ...
Gene therapy 9 (5), 320-326, 2002
1942002
The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages
UFO Luhmann, S Robbie, PMG Munro, SE Barker, Y Duran, V Luong, ...
Investigative ophthalmology & visual science 50 (12), 5934-5943, 2009
1892009
Gene therapy progress and prospects: the eye
JWB Bainbridge, MH Tan, RR Ali
Gene therapy 13 (16), 1191-1197, 2006
1552006
Progress and prospects: gene therapy clinical trials (part 1)
E Alton
Gene therapy 14 (20), 1439-1447, 2007
1512007
Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy
M Tschernutter, FC Schlichtenbrede, S Howe, KS Balaggan, PM Munro, ...
Gene therapy 12 (8), 694-701, 2005
1492005
AAV-Mediated gene transfer slows photoreceptor loss in the RCS rat model of retinitis pigmentosa
AJ Smith, FC Schlichtenbrede, M Tschernutter, JW Bainbridge, ...
Molecular therapy 8 (2), 188-195, 2003
1482003
Gene replacement therapy in the retinal degeneration slow (rds) mouse: the effect on retinal degeneration following partial transduction of the retina
GM Sarra, C Stephens, M de Alwis, JWB Bainbridge, AJ Smith, ...
Human Molecular Genetics 10 (21), 2353-2361, 2001
1432001
Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy
LS Carvalho, J Xu, RA Pearson, AJ Smith, JW Bainbridge, LM Morris, ...
Human molecular genetics 20 (16), 3161-3175, 2011
1412011
Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 …
MH Tan, AJ Smith, B Pawlyk, X Xu, X Liu, JB Bainbridge, M Basche, ...
Human molecular genetics 18 (12), 2099-2114, 2009
1302009
Intraocular gene delivery of ciliary neurotrophic factor results in significant loss of retinal function in normal mice and in the Prph2 Rd2/Rd2 model of retinal degeneration
FC Schlichtenbrede, A MacNeil, JWB Bainbridge, M Tschernutter, ...
Gene therapy 10 (6), 523-527, 2003
1282003
AAV-mediated gene therapy for retinal disorders: from mouse to man
PK Buch, JW Bainbridge, RR Ali
Gene therapy 15 (11), 849-857, 2008
1242008
Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and …
RA Pearson, AC Barber, EL West, RE MacLaren, Y Duran, JW Bainbridge, ...
Cell transplantation 19 (4), 487-503, 2010
1212010
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Articles 1–20