Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation ME Gurney, H Pu, AY Chiu, MC Dal Canto, CY Polchow, DD Alexander, ... Science 264 (5166), 1772-1775, 1994 | 4945 | 1994 |
Neuregulin 1 and susceptibility to schizophrenia H Stefansson, H Petursson, E Sigurdsson, V Steinthorsdottir, ... The American Journal of Human Genetics 71 (4), 877-892, 2002 | 2102 | 2002 |
Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity R Yan, MJ Bienkowski, ME Shuck, H Miao, MC Tory, AM Pauley, ... Nature 402 (6761), 533-537, 1999 | 2069 | 1999 |
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes V Steinthorsdottir, G Thorleifsson, I Reynisdottir, R Benediktsson, ... Nature genetics 39 (6), 770-775, 2007 | 1273 | 2007 |
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke A Helgadottir, A Manolescu, G Thorleifsson, S Gretarsdottir, H Jonsdottir, ... Nature genetics 36 (3), 233-239, 2004 | 1241 | 2004 |
aph-1 and pen-2 are required for Notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation R Francis, G McGrath, J Zhang, DA Ruddy, M Sym, J Apfeld, M Nicoll, ... Developmental cell 3 (1), 85-97, 2002 | 1202 | 2002 |
Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation H Fujimura, CA Altar, R Chen, T Nakamura, T Nakahashi, J Kambayashi, ... Thrombosis and haemostasis 87 (04), 728-734, 2002 | 977 | 2002 |
Benefit of vitamin E, riluzole, and gababapentin in a transgenic model of familial amyotrophic lateral sclerosis ME Gurney, FB Cutting, P Zhai, A Doble, CP Taylor, PK Andrus, ED Hall Annals of neurology 39 (2), 147-157, 1996 | 837 | 1996 |
The gene encoding phosphodiesterase 4D confers risk of ischemic stroke S Gretarsdottir, G Thorleifsson, ST Reynisdottir, A Manolescu, S Jonsdottir, ... Nature genetics 35 (2), 131-138, 2003 | 768 | 2003 |
Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis JA Johnston, MJ Dalton, ME Gurney, RR Kopito Proceedings of the National Academy of Sciences 97 (23), 12571-12576, 2000 | 737 | 2000 |
Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS ED Hall, JA Oostveen, ME Gurney Glia 23 (3), 249-256, 1998 | 686 | 1998 |
Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic … MC Dal Canto, ME Gurney Brain research 676 (1), 25-40, 1995 | 552 | 1995 |
Hormone-induced sexual differentiation of brain and behavior in zebra finches ME Gurney, M Konishi Science 208 (4450), 1380-1383, 1980 | 538 | 1980 |
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog C Öberg, J Li, A Pauley, E Wolf, M Gurney, U Lendahl Journal of Biological Chemistry 276 (38), 35847-35853, 2001 | 536 | 2001 |
Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. MC Dal Canto, ME Gurney The American journal of pathology 145 (6), 1271, 1994 | 516 | 1994 |
Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. PH Tu, P Raju, KA Robinson, ME Gurney, JQ Trojanowski, VM Lee Proceedings of the National Academy of Sciences 93 (7), 3155-3160, 1996 | 507 | 1996 |
Effects of a 5-lipoxygenase–activating protein inhibitor on biomarkers associated with risk of myocardial infarction: a randomized trial H Hakonarson, S Thorvaldsson, A Helgadottir, D Gudbjartsson, F Zink, ... Jama 293 (18), 2245-2256, 2005 | 451 | 2005 |
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation G Wu, S Lyapina, I Das, J Li, M Gurney, A Pauley, I Chui, RJ Deshaies, ... Molecular and cellular biology, 2001 | 444 | 2001 |
Hormonal control of cell form and number in the zebra finch song system ME Gurney Journal of Neuroscience 1 (6), 658-673, 1981 | 438 | 1981 |
Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety AB Burgin, OT Magnusson, J Singh, P Witte, BL Staker, JM Bjornsson, ... Nature biotechnology 28 (1), 63-70, 2010 | 422 | 2010 |