| Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB DD Sarbassov, SM Ali, S Sengupta, JH Sheen, PP Hsu, AF Bagley, ... Molecular cell 22 (2), 159-168, 2006 | 3270 | 2006 |
| Cancer cell metabolism: Warburg and beyond PP Hsu, DM Sabatini Cell 134 (5), 703-707, 2008 | 2859 | 2008 |
| Functional genomics reveal that the serine synthesis pathway is essential in breast cancer R Possemato, KM Marks, YD Shaul, ME Pacold, D Kim, K Birsoy, ... Nature 476 (7360), 346-350, 2011 | 1635 | 2011 |
| The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling PP Hsu, SA Kang, J Rameseder, Y Zhang, KA Ottina, D Lim, TR Peterson, ... science 332 (6035), 1317-1322, 2011 | 1202 | 2011 |
| Tyrosine kinase gene rearrangements in epithelial malignancies AT Shaw, PP Hsu, MM Awad, JA Engelman Nature reviews Cancer 13 (11), 772-787, 2013 | 318 | 2013 |
| A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast TJ Proszynski, RW Klemm, M Gravert, PP Hsu, Y Gloor, J Wagner, ... Proceedings of the National Academy of Sciences 102 (50), 17981-17986, 2005 | 156 | 2005 |
| Induction of a timed metabolic collapse to overcome cancer chemoresistance N Van Gastel, JB Spinelli, A Sharda, A Schajnovitz, N Baryawno, C Rhee, ... Cell Metabolism 32 (3), 391-403. e6, 2020 | 99 | 2020 |
| Identification of DHODH as a therapeutic target in small cell lung cancer L Li, SR Ng, CI Colón, BJ Drapkin, PP Hsu, Z Li, CS Nabel, CA Lewis, ... Science translational medicine 11 (517), eaaw7852, 2019 | 96 | 2019 |
| Nucleocytoplasmic shuttling of the Golgi phosphatidylinositol 4-kinase Pik1 is regulated by 14-3-3 proteins and coordinates Golgi function with cell growth L Demmel, M Beck, C Klose, AL Schlaitz, Y Gloor, PP Hsu, J Havlis, ... Molecular biology of the cell 19 (3), 1046-1061, 2008 | 75 | 2008 |
| Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells AJ Schwartz, JW Goyert, S Solanki, SA Kerk, B Chen, C Castillo, PP Hsu, ... Nature metabolism 3 (7), 969-982, 2021 | 60 | 2021 |
| Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1–S6K pathway signaling RA Lindquist, KA Ottina, DB Wheeler, PP Hsu, CC Thoreen, DA Guertin, ... Genome research 21 (3), 433-446, 2011 | 48 | 2011 |
| Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1 R Romero, FJ Sánchez-Rivera, PMK Westcott, KL Mercer, A Bhutkar, ... Nature Cancer 1 (6), 589-602, 2020 | 46 | 2020 |
| Lung cancer: a wily genetic opponent PP Hsu, AT Shaw Cell 169 (5), 777-779, 2017 | 17 | 2017 |
| Metabolic and chemical architecture of the mammalian circadian clock I Laothamatas, ES Rasmussen, CB Green, JS Takahashi Cell Chemical Biology, 2023 | 10 | 2023 |
| Screening in serum-derived medium reveals differential response to compounds targeting metabolism KL Abbott, A Ali, D Casalena, BT Do, R Ferreira, JH Cheah, CK Soule, ... Cell chemical biology 30 (9), 1156-1168. e7, 2023 | 8 | 2023 |
| Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung AS Conchola, T Frum, Z Xiao, PP Hsu, K Kaur, MS Downey, RFC Hein, ... Proceedings of the National Academy of Sciences 120 (24), e2210113120, 2023 | 8 | 2023 |
| Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress BT Do, PP Hsu, SY Vermeulen, Z Wang, T Hirz, KL Abbott, N Aziz, ... bioRxiv, 2022.08. 16.503984, 2022 | 4 | 2022 |
| DHODH inhibitors in the treatment of acute myeloid leukemia: Defining the mechanism of action and the basis of the metabolic therapeutic window PP Hsu, Y Kfoury, N Aziz, J Elkhoury, B Hallgren, DT Scadden, ... Blood 132, 2716, 2018 | 3 | 2018 |
| Functional genomics reveal that the serine synthesis pathway is essential in breast cancer S Sethumadhavan, HK Woo, HG Jang, AK Jha, WW Chen, FG Barrett, ... Nature 476, 346350, 2011 | 3 | 2011 |
| Opposing roles for TGFβ-and BMP-signaling during nascent alveolar differentiation in the developing human lung T Frum, PP Hsu, RFC Hein, AS Conchola, CJ Zhang, OR Utter, A Anand, ... NPJ Regenerative Medicine 8 (1), 48, 2023 | 2 | 2023 |
