Time-restricted role for dendritic activation of the mTOR-p70S6K pathway in the induction of late-phase long-term potentiation in the CA1 M Cammalleri, R Lütjens, F Berton, AR King, C Simpson, W Francesconi, ... Proceedings of the National Academy of Sciences 100 (24), 14368-14373, 2003 | 381 | 2003 |
Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region (vol 22, pg … PP Sanna, M Cammalleri, F Berton, C Simpson, R Lutjens, FE Bloom, ... Journal of Neuroscience 22 (23), 10507-10507, 2002 | 309 | 2002 |
Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region PP Sanna, M Cammalleri, F Berton, C Simpson, R Lutjens, FE Bloom, ... Journal of Neuroscience 22 (9), 3359-3365, 2002 | 305 | 2002 |
Regulation of microtubule dynamics by the neuronal growth-associated protein SCG10 BM Riederer, V Pellier, B Antonsson, G Di Paolo, SA Stimpson, R Lütjens, ... Proceedings of the National Academy of Sciences 94 (2), 741-745, 1997 | 220 | 1997 |
ERK regulation in chronic ethanol exposure and withdrawal PP Sanna, C Simpson, R Lutjens, G Koob Brain research 948 (1-2), 186-191, 2002 | 151 | 2002 |
Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction SH Ahmed, R Lutjens, LD van der Stap, D Lekic, V Romano-Spica, ... Proceedings of the National Academy of Sciences 102 (32), 11533-11538, 2005 | 149 | 2005 |
Targeting of SCG10 to the area of the Golgi complex is mediated by its NH2-terminal region G Di Paolo, R Lutjens, V Pellier, SA Stimpson, MH Beuchat, S Catsicas, ... Journal of Biological Chemistry 272 (8), 5175-5182, 1997 | 109 | 1997 |
ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization M Kalinichev, M Rouillier, F Girard, I Royer-Urios, B Bournique, T Finn, ... Journal of Pharmacology and Experimental Therapeutics 344 (3), 624-636, 2013 | 101 | 2013 |
ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization M Kalinichev, M Rouillier, F Girard, I Royer-Urios, B Bournique, T Finn, ... Journal of Pharmacology and Experimental Therapeutics 344 (3), 624-636, 2013 | 101 | 2013 |
ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization M Kalinichev, M Rouillier, F Girard, I Royer-Urios, B Bournique, T Finn, ... Journal of Pharmacology and Experimental Therapeutics 344 (3), 624-636, 2013 | 100 | 2013 |
Identification of in Vitro Phosphorylation Sites in the Growth Cone Protein SCG10 EFFECT OF PHOSPHORYLATION SITE MUTANTS ON MICROTUBULE-DESTABILIZING ACTIVITY B Antonsson, DB Kassel, G Di Paolo, R Lutjens, BM Riederer, ... Journal of Biological Chemistry 273 (14), 8439-8446, 1998 | 100 | 1998 |
Localization and targeting of SCG10 to the trans‐Golgi apparatus and growth cone vesicles R Lutjens, M Igarashi, V Pellier, H Blasey, G Di Paolo, E Ruchti, C Pfulg, ... European Journal of Neuroscience 12 (7), 2224-2234, 2000 | 89 | 2000 |
Lateral allosterism in the glucagon receptor family: glucagon-like peptide 1 induces G-protein-coupled receptor heteromer formation D Schelshorn, F Joly, S Mutel, C Hampe, B Breton, V Mutel, R Lütjens Molecular pharmacology 81 (3), 309-318, 2012 | 81 | 2012 |
Differential distribution of stathmin and SCG10 in developing neurons in culture G Di Paolo, R Lutjens, A Osen‐Sand, A Sobel, S Catsicas, G Grenningloh Journal of neuroscience research 50 (6), 1000-1009, 1997 | 72 | 1997 |
Pharmacological Characterization of JNJ-40068782, a New Potent, Selective, and Systemically Active Positive Allosteric Modulator of the mGlu2 Receptor and Its Radioligand [3H … H Lavreysen, X Langlois, A Ahnaou, W Drinkenburg, P te Riele, ... Journal of Pharmacology and Experimental Therapeutics 346 (3), 514-527, 2013 | 69 | 2013 |
Preclinical evaluation of the antipsychotic potential of the mGlu2‐positive allosteric modulator JNJ‐40411813 H Lavreysen, X Langlois, LV Donck, JMC Nuñez, S Pype, R Lütjens, ... Pharmacology Research & Perspectives 3 (2), 2015 | 45 | 2015 |
Pharmacological and pharmacokinetic properties of JNJ‐40411813, a positive allosteric modulator of the mGlu2 receptor H Lavreysen, A Ahnaou, W Drinkenburg, X Langlois, C Mackie, S Pype, ... Pharmacology Research & Perspectives 3 (1), 2015 | 43 | 2015 |
1, 4-disubstituted 3-cyano-pyridone derivatives and their use as positive mGluR2-receptor modulators JM Cid-Núñez, AA Trabanco-Suárez, GJ Macdonald, GAJ Duvey, ... US Patent 8,299,101, 2012 | 42 | 2012 |
3-cyano-4-(4-phenyl-piperidin-1-yl)-pyridin-2-one derivatives JM Cid-Núñez, GAJ Duvey, RJ Lütjens, GJ MacDonald, ... US Patent App. 12/529,632, 2008 | 41 | 2008 |
Purification, Characterization, andin VitroPhosphorylation of the Neuron-Specific Membrane-Associated Protein SCG10 B Antonsson, R Lütjens, G Di Paolo, D Kassel, B Allet, A Bernard, ... Protein expression and purification 9 (3), 363-371, 1997 | 40 | 1997 |