John E Burke

Cited by

	All	Since 2018
Citations	10362	7948
h-index	47	41
i10-index	88	86

2400

1200

600

1800

200920102011201220132014201520162017201820192020202120222023104 135 175 183 259 259 359 367 517 543 781 906 1259 2110 2326

Public access

View all

92 articles

10 articles

available

not available

Based on funding mandates

Co-authors

Roger L WilliamsGroup leader, Medical Research Council, Laboratory of Molecular BiologyVerified email at mrc-lmb.cam.ac.uk
Meredith L JenkinsLab Manager, University of VictoriaVerified email at uvic.ca
Glenn R. MassonUniversity of Dundee, School of MedicineVerified email at dundee.ac.uk
Oscar VadasPostdoc at the Medical Research Council - Laboratory of Molecular Biology, Cambridge, UKVerified email at unige.ch
Jacob A McPhailPhD, R&D Scientist at StressMarq BiosciencesVerified email at uvic.ca
Manoj RathinaswamyUniversity of VictoriaVerified email at uvic.ca
Gillian Leigh DornanLeibniz-ForschungsInstitut für Molekulare PharmakologieVerified email at fmp-berlin.de
Braden D. SiempelkampUniversity of VictoriaVerified email at uvic.ca
jan steyaertVIB-VUB center for Structural Biology, BrusselsVerified email at vub.ac.be
Els Pardonvrije universiteit brusselVerified email at vub.ac.be
Yuan-Hao Hsu/許員豪Department of Chemistry, Tunghai University/東海大學化學系Verified email at thu.edu.tw
Martin J BoulangerUniversity of VictoriaVerified email at uvic.ca
Calvin YipAssociate Professor of Biochemistry and Molecular Biology, the University of British ColumbiaVerified email at ubc.ca
Yohei OhashiLaboratory of Molecular Biology, Medical Research CouncilVerified email at mrc-lmb.cam.ac.uk
Alex BerndtResearch Scientist MRC-LMBVerified email at mrc-lmb.cam.ac.uk
Hashem DboukVerified email at phd.einstein.yu.edu
George KokotosProfessor of Organic Chemistry, National and Kapodistrian University of AthensVerified email at chem.uoa.gr
Alisdair BorastonProfessor of Biochemistry and Microbiology, University of VictoriaVerified email at uvic.ca
Alan SmrckaProfessor of Pharmacology, University of MichiganVerified email at umich.edu
Joseph J. FalkeDirector of Molecular Biophysics, Prof. of Chemistry & Biochemistry, CU BoulderVerified email at colorado.edu

John E Burke

Professor of Biochemistry and Microbiology, University of Victoria

Verified email at uvic.ca - Homepage

X-ray crystallography HDX-MS hydrogen exchange PI3K phosphoinositides


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Accurate prediction of protein structures and interactions using a three-track neural network M Baek, F DiMaio, I Anishchenko, J Dauparas, S Ovchinnikov, GR Lee, ... Science 373 (6557), 871-876, 2021	2718	2021
Phospholipase A2 structure/function, mechanism, and signaling1 JE Burke, EA Dennis Journal of lipid research 50, S237-S242, 2009	1066	2009
Phospholipase A₂ Biochemistry JE Burke, EA Dennis Cardiovascular drugs and therapy 23, 49-59, 2009	527	2009
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ... Nature methods 16 (7), 595-602, 2019	459	2019
Structural basis for activation and inhibition of class I phosphoinositide 3-kinases O Vadas, JE Burke, X Zhang, A Berndt, RL Williams Science signaling 4 (195), re2-re2, 2011	294	2011
Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA) JE Burke, O Perisic, GR Masson, O Vadas, RL Williams Proceedings of the National Academy of Sciences, 2012	277	2012
Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes K Rostislavleva, N Soler, Y Ohashi, L Zhang, E Pardon, JE Burke, ... Science 350 (6257), aac7365, 2015	238	2015
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors N Kato, E Comer, T Sakata-Kato, A Sharma, M Sharma, M Maetani, ... Nature 538 (7625), 344-349, 2016	235	2016
Synergy in activating class I PI3Ks JE Burke, RL Williams Trends in biochemical sciences 40 (2), 88-100, 2015	186	2015
Structural basis for regulation of phosphoinositide kinases and their involvement in human disease JE Burke Molecular cell 71 (5), 653-673, 2018	182	2018
G protein–coupled receptor–mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness HA Dbouk, O Vadas, A Shymanets, JE Burke, RS Salamon, BD Khalil, ... Science signaling 5 (253), ra89-ra89, 2012	160	2012
Molecular determinants of PI3Kγ-mediated activation downstream of G-protein–coupled receptors (GPCRs) O Vadas, HA Dbouk, A Shymanets, O Perisic, JE Burke, WF Abi Saab, ... Proceedings of the National Academy of Sciences 110 (47), 18862-18867, 2013	151	2013
Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi G D’Angelo, T Uemura, CC Chuang, E Polishchuk, M Santoro, ... Nature 501 (7465), 116-120, 2013	147	2013
An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery GR Masson, ML Jenkins, JE Burke Expert opinion on drug discovery 12 (10), 981-994, 2017	138	2017
Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors JE Burke, AJ Inglis, O Perisic, GR Masson, SH McLaughlin, F Rutaganira, ... Science 344 (6187), 1035-1038, 2014	138	2014
Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne TET Mevissen, Y Kulathu, MPC Mulder, PP Geurink, SL Maslen, M Gersch, ... Nature 538 (7625), 402-405, 2016	136	2016
Novel roles of phosphoinositides in signaling, lipid transport, and disease GRV Hammond, JE Burke Current Opinion in Cell Biology 63, 57-67, 2020	114	2020
Dynamics of the Phosphoinositide 3-Kinase p110 [delta] Interaction with p85 [alpha] and Membranes Reveals Aspects of Regulation Distinct from p110 [alpha] JE Burke, O Vadas, A Berndt, T Finegan, O Perisic, RL Williams Structure 19 (8), 1127-1137, 2011	112	2011
Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1 GL Dornan, BD Siempelkamp, ML Jenkins, O Vadas, CL Lucas, JE Burke Proceedings of the National Academy of Sciences 114 (8), 1982-1987, 2017	100	2017
Potent and Selective Fluoroketone Inhibitors of Group VIA Calcium-Independent Phospholipase A₂ G Kokotos, YH Hsu, JE Burke, C Baskakis, CG Kokotos, V Magrioti, ... Journal of medicinal chemistry 53 (9), 3602-3610, 2010	99	2010

The system can't perform the operation now. Try again later.

Articles 1–20

Citations per year

Duplicate citations

Merged citations

Add co-authorsCo-authors

Follow

Cited by

Co-authors