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Flavio Curnis
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Enhancement of tumor necrosis factor α antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)
F Curnis, A Sacchi, L Borgna, F Magni, A Gasparri, A Corti
Nature biotechnology 18 (11), 1185-1190, 2000
5422000
Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells
F Curnis, G Arrigoni, A Sacchi, L Fischetti, W Arap, R Pasqualini, A Corti
Cancer research 62 (3), 867-874, 2002
3792002
Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration
F Curnis, A Sacchi, A Corti
The Journal of clinical investigation 110 (4), 475-482, 2002
3332002
Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif
G Colombo, F Curnis, GMS De Mori, A Gasparri, C Longoni, A Sacchi, ...
Journal of Biological Chemistry 277 (49), 47891-47897, 2002
2522002
Spontaneous formation of L-isoaspartate and gain of function in fibronectin
F Curnis, R Longhi, L Crippa, A Cattaneo, E Dondossola, A Bachi, A Corti
Journal of Biological Chemistry 281 (47), 36466-36476, 2006
2312006
Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function
M Pieroni, A Corti, B Tota, F Curnis, T Angelone, B Colombo, MC Cerra, ...
European heart journal 28 (9), 1117-1127, 2007
2242007
The neovasculature homing motif NGR: more than meets the eye
A Corti, F Curnis, W Arap, R Pasqualini
Blood, The Journal of the American Society of Hematology 112 (7), 2628-2635, 2008
2222008
Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-α
A Sacchi, A Gasparri, C Gallo-Stampino, S Toma, F Curnis, A Corti
Clinical Cancer Research 12 (1), 175-182, 2006
1912006
Coupling Tumor Necrosis Factor-α with αV Integrin Ligands Improves Its Antineoplastic Activity
F Curnis, A Gasparri, A Sacchi, R Longhi, A Corti
Cancer research 64 (2), 565-571, 2004
1822004
Targeting TNF-α to neoangiogenic vessels enhances lymphocyte infiltration in tumors and increases the therapeutic potential of immunotherapy
A Calcinotto, M Grioni, E Jachetti, F Curnis, A Mondino, G Parmiani, ...
The Journal of Immunology 188 (6), 2687-2694, 2012
1482012
Roles of tumor necrosis factor p55 and p75 receptors in TNF-α-induced vascular permeability
E Ferrero, MR Zocchi, E Magni, MC Panzeri, F Curnis, C Rugarli, ...
American Journal of Physiology-Cell Physiology 281 (4), C1173-C1179, 2001
1452001
Chromogranin A protects vessels against tumor necrosis factor α‐induced vascular leakage
E Ferrero, S Scabini, E Magni, C Foglieni, D Belloni, B Colombo, F Curnis, ...
The FASEB journal 18 (3), 554-556, 2004
1422004
Targeted drug delivery and penetration into solid tumors
A Corti, F Pastorino, F Curnis, W Arap, M Ponzoni, R Pasqualini
Medicinal research reviews 32 (5), 1078-1091, 2012
1352012
Targeted delivery of IFNγ to tumor vessels uncouples antitumor from counterregulatory mechanisms
F Curnis, A Gasparri, A Sacchi, A Cattaneo, F Magni, A Corti
Cancer research 65 (7), 2906-2913, 2005
1182005
Structural basis for the interaction of isoDGR with the RGD-binding site of αvβ3 integrin
A Spitaleri, S Mari, F Curnis, C Traversari, R Longhi, C Bordignon, A Corti, ...
Journal of Biological Chemistry 283 (28), 19757-19768, 2008
1172008
Structure-activity relationships of chromogranin A in cell adhesion: identification of an adhesion site for fibroblasts and smooth muscle cells
S Ratti, F Curnis, R Longhi, B Colombo, A Gasparri, F Magni, E Manera, ...
Journal of Biological Chemistry 275 (38), 29257-29263, 2000
1052000
Tumor pretargeting with avidin improves the therapeutic index of biotinylated tumor necrosis factor α in mouse models
A Gasparri, M Moro, F Curnis, A Sacchi, S Pagano, F Veglia, G Casorati, ...
Cancer research 59 (12), 2917-2923, 1999
1041999
Isoaspartate-dependent molecular switches for integrin–ligand recognition
A Corti, F Curnis
Journal of cell science 124 (4), 515-522, 2011
1032011
Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching
F Curnis, A Cattaneo, R Longhi, A Sacchi, AM Gasparri, F Pastorino, ...
Journal of biological chemistry 285 (12), 9114-9123, 2010
932010
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma
M Loi, S Marchiò, P Becherini, D Di Paolo, M Soster, F Curnis, C Brignole, ...
Journal of controlled release 145 (1), 66-73, 2010
902010
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