Further evidence for the cholinergic hypothesis of aging and dementia from the canine model of aging JA Araujo, CM Studzinski, NW Milgram Progress in Neuro-Psychopharmacology and Biological Psychiatry 29 (3), 411-422, 2005 | 177 | 2005 |
Visuospatial function in the beagle dog: an early marker of cognitive decline in a model of human aging and dementia CM Studzinski, LA Christie, JA Araujo, WMI Burnham, E Head, ... Neurobiology of learning and memory 86 (2), 197-204, 2006 | 160 | 2006 |
The canine model of human cognitive aging and dementia: pharmacological validity of the model for assessment of human cognitive-enhancing drugs CM Studzinski, JA Araujo, NW Milgram Progress in Neuro-Psychopharmacology and Biological Psychiatry 29 (3), 489-498, 2005 | 116 | 2005 |
A ketogenic diet improves motor performance but does not affect β-amyloid levels in a mouse model of Alzheimer's disease TL Beckett, CM Studzinski, JN Keller, MP Murphy, DM Niedowicz Brain research 1505, 61-67, 2013 | 100 | 2013 |
Induction of ketosis may improve mitochondrial function and decrease steady-state amyloid-β precursor protein (APP) levels in the aged dog CM Studzinski, WA MacKay, TL Beckett, ST Henderson, MP Murphy, ... Brain research 1226, 209-217, 2008 | 99 | 2008 |
Effects of short‐term Western diet on cerebral oxidative stress and diabetes related factors in APP× PS1 knock‐in mice CM Studzinski, F Li, AJ Bruce‐Keller, SO Fernandez‐Kim, L Zhang, ... Journal of neurochemistry 108 (4), 860-866, 2009 | 96 | 2009 |
Amyloid-β peptide and oligomers in the brain and cerebrospinal fluid of aged canines E Head, V Pop, F Sarsoza, R Kayed, TL Beckett, CM Studzinski, JL Tomic, ... Journal of Alzheimer's Disease 20 (2), 637-646, 2010 | 93 | 2010 |
Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease Y Liu, C Studzinski, T Beckett, H Guan, MA Hersh, MP Murphy, R Klein, ... Molecular Therapy 17 (8), 1381-1386, 2009 | 86 | 2009 |
Circulating neprilysin clears brain amyloid Y Liu, C Studzinski, T Beckett, MP Murphy, RL Klein, LB Hersh Molecular and Cellular Neuroscience 45 (2), 101-107, 2010 | 80 | 2010 |
Leptin regulates amyloid β production via the γ-secretase complex DM Niedowicz, CM Studzinski, AM Weidner, TL Platt, KN Kingry, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (3), 439-444, 2013 | 58 | 2013 |
A comparison of egocentric and allocentric age-dependent spatial learning in the beagle dog LA Christie, CM Studzinski, JA Araujo, CSK Leung, CJ Ikeda-Douglas, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 29 (3), 361-369, 2005 | 56 | 2005 |
Assessment of nutritional interventions for modification of age-associated cognitive decline using a canine model of human aging JA Araujo, CM Studzinski, E Head, CW Cotman, NW Milgram Age 27, 27-37, 2005 | 51 | 2005 |
Age-related loss of phospholipid asymmetry in APPNLh/APPNLh x PS-1P264L/PS-1P264L human double mutant knock-in mice: Relevance to Alzheimer disease MLB Lange, DS Clair, WR Markesbery, CM Studzinski, MP Murphy, ... Neurobiology of disease 38 (1), 104-115, 2010 | 49 | 2010 |
Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs MP Murphy, J Morales, TL Beckett, G Astarita, D Piomelli, A Weidner, ... Journal of Alzheimer's disease 22 (1), 135-150, 2010 | 42 | 2010 |
Aβ aggregation profiles and shifts in APP processing favor amyloidogenesis in canines V Pop, E Head, NC Berchtold, CG Glabe, CM Studzinski, AM Weidner, ... Neurobiology of aging 33 (1), 108-120, 2012 | 35 | 2012 |
Comparison of the cognitive palatability assessment protocol and the two-pan test for use in assessing palatability of two similar foods in dogs JA Araujo, CM Studzinski, BT Larson, NW Milgram American journal of veterinary research 65 (11), 1490-1496, 2004 | 32 | 2004 |
Effects of nonsteroidal anti-inflammatory drugs on amyloid-β pathology in mouse skeletal muscle TL Beckett, DM Niedowicz, CM Studzinski, AM Weidner, RL Webb, ... Neurobiology of disease 39 (3), 449-456, 2010 | 25 | 2010 |
Cognitive function and aging in beagle dogs JA Araujo, CM Studzinski, CT Siwak, E Head, NW Milgram Conference Proceedings of the American College of Veterinary Internal …, 2004 | 8 | 2004 |
Use of phenserine and analogs to treat behavioral problems and improve trainability J Araujo, W Milgram, C Studzinski, N Greig, D Ingram US Patent App. 11/453,564, 2007 | 3 | 2007 |
P2-022 The effects of age and scopolamine on skilled motor function in dogs: further evidence of age-dependent cholinergic dysfunction JA Araujo, CM Studzinski, NW Milgram Neurobiology of Aging, S230, 2004 | 1 | 2004 |