| Cloning, Sequencing, Analysis, and Heterologous Expression of the Fredericamycin Biosynthetic Gene Cluster from Streptomyces griseus E Wendt-Pienkowski, Y Huang, J Zhang, B Li, H Jiang, H Kwon, ... Journal of the American Chemical Society 127 (47), 16442-16452, 2005 | 139 | 2005 |
| Infection microenvironment-related antibacterial nanotherapeutic strategies Z Wang, X Liu, Y Duan, Y Huang Biomaterials 280, 121249, 2022 | 117 | 2022 |
| Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries JM Astle, LS Simpson, Y Huang, MM Reddy, R Wilson, S Connell, ... Chemistry & biology 17 (1), 38-45, 2010 | 112 | 2010 |
| Strain prioritization and genome mining for enediyne natural products X Yan, H Ge, T Huang, Hindra, D Yang, Q Teng, I Crnovčić, X Li, ... MBio 7 (6), 10.1128/mbio. 02104-16, 2016 | 95 | 2016 |
| Hydrogenation of carbon dioxide catalyzed by ruthenium trimethylphosphine complexes Effect of gas pressure and additives on rate in the liquid phase CA Thomas, RJ Bonilla, Y Huang, PG Jessop Canadian Journal of Chemistry 79 (5-6), 719-724, 2001 | 93 | 2001 |
| Discovery of the leinamycin family of natural products by mining actinobacterial genomes G Pan, Z Xu, Z Guo, Hindra, M Ma, D Yang, H Zhou, Y Gansemans, X Zhu, ... Proceedings of the National Academy of Sciences 114 (52), E11131-E11140, 2017 | 92 | 2017 |
| Eurotium cristatum, a potential probiotic fungus from Fuzhuan brick tea, alleviated obesity in mice by modulating gut microbiota D Kang, M Su, Y Duan, Y Huang Food & Function 10 (8), 5032-5045, 2019 | 72 | 2019 |
| Strain prioritization for natural product discovery by a high-throughput real-time PCR method Hindra, T Huang, D Yang, JD Rudolf, P Xie, G Xie, Q Teng, JR Lohman, ... Journal of natural products 77 (10), 2296-2303, 2014 | 69 | 2014 |
| The Application of Ribosome Engineering to Natural Product Discovery and Yield Improvement in Streptomyces S Zhu, Y Duan, Y Huang Antibiotics 8 (3), 133, 2019 | 49 | 2019 |
| Leinamycin E1 acting as an anticancer prodrug activated by reactive oxygen species SX Huang, BS Yun, M Ma, HS Basu, DR Church, G Ingenhorst, Y Huang, ... Proceedings of the National Academy of Sciences 112 (27), 8278-8283, 2015 | 48 | 2015 |
| Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion M Ma, ME Rateb, Q Teng, D Yang, JD Rudolf, X Zhu, Y Huang, LX Zhao, ... Journal of natural products 78 (10), 2471-2480, 2015 | 40 | 2015 |
| A point cloud-based deep learning strategy for protein–ligand binding affinity prediction Y Wang, S Wu, Y Duan, Y Huang Briefings in Bioinformatics 23 (1), bbab474, 2022 | 38 | 2022 |
| Ribosome engineering and fermentation optimization leads to overproduction of tiancimycin A, a new enediyne natural product from Streptomyces sp. CB03234 L Liu, J Pan, Z Wang, X Yan, D Yang, X Zhu, B Shen, Y Duan, Y Huang Journal of Industrial Microbiology and Biotechnology 45 (3), 141-151, 2018 | 37 | 2018 |
| Bifunctional acyltransferase/decarboxylase LnmK as the missing link for β-alkylation in polyketide biosynthesis T Liu, Y Huang, B Shen Journal of the American Chemical Society 131 (20), 6900-6901, 2009 | 37 | 2009 |
| Titer improvement and pilot-scale production of platensimycin from Streptomyces platensis SB12026 J Shi, J Pan, L Liu, D Yang, S Lu, X Zhu, B Shen, Y Duan, Y Huang Journal of Industrial Microbiology and Biotechnology 43 (7), 1027-1035, 2016 | 32 | 2016 |
| A dedicated phosphopantetheinyl transferase for the fredericamycin polyketide synthase from Streptomyces griseus Y Huang, E Wendt-Pienkowski, B Shen Journal of biological chemistry 281 (40), 29660-29668, 2006 | 32 | 2006 |
| Streptomycin‐induced ribosome engineering complemented with fermentation optimization for enhanced production of 10‐membered enediynes tiancimycin‐A and tiancimycin‐D Z Zhuang, C Jiang, F Zhang, R Huang, L Yi, Y Huang, X Yan, Y Duan, ... Biotechnology and Bioengineering 116 (6), 1304-1314, 2019 | 31 | 2019 |
| Recycling of Chinese herb residues by endophytic and probiotic fungus Aspergillus cristatus CB10002 for the production of medicinal valuable anthraquinones W Kong, C Huang, J Shi, Y Li, X Jiang, Q Duan, Y Huang, Y Duan, X Zhu Microbial Cell Factories 18, 1-11, 2019 | 30 | 2019 |
| Biosynthesis of thiocarboxylic acid-containing natural products LB Dong, JD Rudolf, D Kang, N Wang, CQ He, Y Deng, Y Huang, ... Nature communications 9 (1), 2362, 2018 | 29 | 2018 |
| Strain improvement by combined UV mutagenesis and ribosome engineering and subsequent fermentation optimization for enhanced 6′-deoxy-bleomycin Z production X Zhu, J Kong, H Yang, R Huang, Y Huang, D Yang, B Shen, Y Duan Applied microbiology and biotechnology 102, 1651-1661, 2018 | 29 | 2018 |
